Cas no 5159-60-4 (6-cyanonaphthalene-2-carboxylic acid)

6-Cyanonaphthalene-2-carboxylic acid is a versatile aromatic compound featuring both cyano and carboxylic acid functional groups on a naphthalene backbone. This structure enables its use as a key intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and advanced materials. The electron-withdrawing cyano group enhances reactivity in nucleophilic substitution and cyclization reactions, while the carboxylic acid moiety allows for further derivatization via esterification, amidation, or metal coordination. Its rigid naphthalene core contributes to stability and planar geometry, making it valuable in the design of conjugated systems for optoelectronic applications. The compound is typically handled under standard laboratory conditions, requiring protection from moisture to maintain purity.
6-cyanonaphthalene-2-carboxylic acid structure
5159-60-4 structure
Product Name:6-cyanonaphthalene-2-carboxylic acid
CAS No:5159-60-4
MF:C12H7NO2
MW:197.189482927322
CID:361895
PubChem ID:12433090
Update Time:2025-05-27

6-cyanonaphthalene-2-carboxylic acid Chemical and Physical Properties

Names and Identifiers

    • 6-Cyano-2-naphthoic acid
    • 6-cyanonaphthalene-2-carboxylic acid
    • 5159-60-4
    • EN300-119561
    • 6-Cyano-2-naphthoicacid
    • CS-0308419
    • F88006
    • 2-Naphthalenecarboxylic acid, 6-cyano-
    • 6-Cyano-naphthalene-2-carboxylic acid
    • DTXSID10498075
    • OZXBANYHKBTOIN-UHFFFAOYSA-N
    • SCHEMBL3561878
    • AKOS022186352
    • Z1262511485
    • Inchi: 1S/C12H7NO2/c13-7-8-1-2-10-6-11(12(14)15)4-3-9(10)5-8/h1-6H,(H,14,15)
    • InChI Key: OZXBANYHKBTOIN-UHFFFAOYSA-N
    • SMILES: OC(C1=CC=C2C=C(C#N)C=CC2=C1)=O

Computed Properties

  • Exact Mass: 197.04771
  • Monoisotopic Mass: 197.047678466g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 1
  • Complexity: 304
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3
  • Topological Polar Surface Area: 61.1?2

Experimental Properties

  • PSA: 61.09

6-cyanonaphthalene-2-carboxylic acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A219007648-1g
6-Cyano-2-naphthoic acid
5159-60-4 95%
1g
$998.00 2023-09-01
Chemenu
CM140254-1g
6-cyano-2-naphthoic acid
5159-60-4 95%
1g
$608 2021-08-05
Chemenu
CM140254-5g
6-cyano-2-naphthoic acid
5159-60-4 95%
5g
$1823 2021-08-05
Chemenu
CM140254-500mg
6-cyano-2-naphthoic acid
5159-60-4 95%
500mg
$*** 2023-03-30
Chemenu
CM140254-10g
6-cyano-2-naphthoic acid
5159-60-4 95%
10g
$*** 2023-03-30
Chemenu
CM140254-1g
6-cyano-2-naphthoic acid
5159-60-4 95%
1g
$*** 2023-03-30
Chemenu
CM140254-5g
6-cyano-2-naphthoic acid
5159-60-4 95%
5g
$*** 2023-03-30
A2B Chem LLC
AG29517-50mg
6-Cyano-2-naphthoic acid
5159-60-4 95%
50mg
$259.00 2024-04-19
A2B Chem LLC
AG29517-100mg
6-Cyano-2-naphthoic acid
5159-60-4 95%
100mg
$369.00 2024-04-19
A2B Chem LLC
AG29517-250mg
6-Cyano-2-naphthoic acid
5159-60-4 95%
250mg
$511.00 2024-04-19

Additional information on 6-cyanonaphthalene-2-carboxylic acid

Comprehensive Analysis of 6-Cyanonaphthalene-2-carboxylic Acid (CAS No. 5159-60-4): Properties, Applications, and Industry Insights

6-Cyanonaphthalene-2-carboxylic acid (CAS No. 5159-60-4) is a specialized organic compound that has garnered significant attention in pharmaceutical and material science research. This naphthalene derivative features a cyano group at the 6-position and a carboxylic acid moiety at the 2-position, making it a versatile building block for synthesizing complex molecules. Its molecular formula, C12H7NO2, and unique structural properties enable applications ranging from fluorescent probes to organic semiconductors.

Recent trends in drug discovery and organic electronics have driven demand for high-purity intermediates like 6-cyanonaphthalene-2-carboxylic acid. Researchers frequently search for "synthesis of naphthalene derivatives" or "applications of cyanocarboxylic acids," reflecting its relevance in cutting-edge projects. The compound’s ability to act as a ligand precursor in metal-organic frameworks (MOFs) has also sparked interest in sustainable energy storage solutions.

From a technical perspective, 5159-60-4 exhibits a melting point of 210–215°C and moderate solubility in polar solvents like DMSO. These properties make it suitable for stepwise organic synthesis, particularly in constructing π-conjugated systems for optoelectronic devices. Industry reports highlight its growing use in developing OLED materials, where its electron-withdrawing cyano group enhances charge transport efficiency.

Environmental and regulatory considerations are increasingly shaping the discourse around such compounds. While 6-cyanonaphthalene-2-carboxylic acid isn’t classified as hazardous under major chemical inventories, manufacturers emphasize green chemistry principles in its production. This aligns with global searches for "eco-friendly synthetic routes" and "biodegradable aromatic compounds," addressing sustainability concerns without compromising performance.

The analytical characterization of this compound typically involves HPLC purity testing (≥98%) and spectroscopic verification (FT-IR, NMR). Quality control protocols for CAS 5159-60-4 have become more stringent due to its pharmaceutical applications, where even minor impurities can affect downstream reactions. This rigor responds to frequent queries about "QC standards for specialty chemicals" in research forums.

Emerging studies explore the compound’s potential in bioimaging and therapeutic agent development. Its naphthalene core provides inherent fluorescence, while the carboxylic acid group allows bioconjugation – features that answer growing demands for "multifunctional diagnostic agents." Such applications position 6-cyanonaphthalene-2-carboxylic acid at the intersection of chemistry and biomedical innovation.

Supply chain dynamics for this fine chemical reflect broader industry shifts. With major producers concentrated in Asia and North America, procurement strategies now emphasize "just-in-time delivery" and "multi-source supplier networks" to mitigate geopolitical risks. These operational considerations complement the scientific aspects of 5159-60-4, making comprehensive knowledge of the compound essential for both researchers and procurement specialists.

Recommended suppliers
Shandong Feiyang Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Feiyang Chemical Co., Ltd
Wuhan ChemNorm Biotech Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Wuhan ChemNorm Biotech Co.,Ltd.
ASIACHEM I&E (JIANGSU) CO., LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
ASIACHEM I&E (JIANGSU) CO., LTD
Changzhou Guanjia Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Changzhou Guanjia Chemical Co., Ltd
Zhangzhou Sinobioway Peptide Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Zhangzhou Sinobioway Peptide Co.,Ltd.