Cas no 51503-08-3 ([4-(tert-butoxy)phenyl]methanol)

[4-(tert-Butoxy)phenyl]methanol is a versatile organic compound featuring a tert-butoxy-substituted phenyl ring with a hydroxymethyl functional group. This structure imparts unique reactivity, making it valuable as an intermediate in pharmaceutical and fine chemical synthesis. The tert-butoxy group enhances steric hindrance and stability, while the hydroxymethyl moiety allows for further functionalization, such as oxidation or esterification. Its well-defined purity and consistent performance make it suitable for use in controlled reactions, particularly in the development of specialty chemicals and active pharmaceutical ingredients (APIs). The compound is typically supplied in high purity to ensure reproducibility in research and industrial applications.
[4-(tert-butoxy)phenyl]methanol structure
51503-08-3 structure
Product Name:[4-(tert-butoxy)phenyl]methanol
CAS No:51503-08-3
MF:C11H16O2
MW:180.243543624878
MDL:MFCD09754585
CID:95397
PubChem ID:3016675
Update Time:2025-06-27

[4-(tert-butoxy)phenyl]methanol Chemical and Physical Properties

Names and Identifiers

    • (4-(tert-Butoxy)phenyl)methanol
    • p-tert-Butoxybenzyl alcohol
    • (4-tert-butoxyphenyl)methanol
    • 4-tert-Butoxybenzyl Alcohol
    • [4-[(2-methylpropan-2-yl)oxy]phenyl]methanol
    • 4-(1,1-dimethylethoxy)Benzenemethanol
    • 4-(TERT-BUTOXY)BENZYL ALCOHOL
    • 4-T-BUTOXYBENZYL ALCOHOL
    • 4-tert-Butoxy-benzylalkohol
    • p-t-Butoxybenzylalkohol
    • (4-TERT-BUTOXY-PHENYL)-METHANOL
    • Benzenemethanol, 4-(1,1-dimethylethoxy)-
    • 4-(tert-Butoxy)benzylalcohol
    • H9N2O3P
    • CL8733
    • RW1233
    • 7182AB
    • 7181AB
    • AM84234
    • TRA0055201
    • AB03109
    • 1-t
    • [4-(tert-butoxy)phenyl]methanol
    • SY015586
    • EN300-1666598
    • Ethyl4-cyclopropyl(hydroxy)methylene-3,5-dioxocyclohexanecarboxylate
    • FT-0650943
    • NS00032293
    • p-tert-Butoxybenzyl alcohol; (4-tert-butoxyphenyl)methanol;4-tert-Butoxybenzyl Alcohol
    • CS-0187914
    • MFCD00082599
    • A871261
    • AKOS015995794
    • AS-46091
    • DTXSID40199487
    • SCHEMBL319906
    • EINECS 257-246-9
    • 4-tert-Butoxybenzylalcohol
    • 51503-08-3
    • MFCD09754585
    • 4-(t-Butoxy)-benzylalkohol
    • HXCIWXCKKJLNMH-UHFFFAOYSA-N
    • DB-071362
    • MDL: MFCD09754585
    • Inchi: 1S/C11H16O2/c1-11(2,3)13-10-6-4-9(8-12)5-7-10/h4-7,12H,8H2,1-3H3
    • InChI Key: HXCIWXCKKJLNMH-UHFFFAOYSA-N
    • SMILES: O(C1C=CC(CO)=CC=1)C(C)(C)C

Computed Properties

  • Exact Mass: 180.11500
  • Monoisotopic Mass: 180.115
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 141
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.1
  • Topological Polar Surface Area: 29.5

Experimental Properties

  • Color/Form: No data avaiable
  • Density: 1.0±0.1 g/cm3
  • Melting Point: No data available
  • Boiling Point: 281.7 ℃ at 760 mmHg
  • Flash Point: 114.7℃
  • Refractive Index: 1.514
  • PSA: 29.46000
  • LogP: 2.35620
  • Vapor Pressure: No data available

[4-(tert-butoxy)phenyl]methanol Security Information

[4-(tert-butoxy)phenyl]methanol Customs Data

  • HS CODE:2909499000
  • Customs Data:

    China Customs Code:

    2909499000

    Overview:

    2909499000 Other ether alcohols and their halogenation\sulfonation\Nitrosative or nitrosative derivatives. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

[4-(tert-butoxy)phenyl]methanol Pricemore >>

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[4-(tert-butoxy)phenyl]methanol Suppliers

Amadis Chemical Company Limited
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(CAS:51503-08-3)[4-(tert-butoxy)phenyl]methanol
Order Number:A871261
Stock Status:in Stock
Quantity:1g/5g/10g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 09:27
Price ($):152.0/248.0/368.0

Additional information on [4-(tert-butoxy)phenyl]methanol

Introduction to [4-(tert-butoxy)phenyl]methanol (CAS No. 51503-08-3)

[4-(tert-butoxy)phenyl]methanol, with the chemical formula C??H??O? and CAS number 51503-08-3, is a significant compound in the field of organic chemistry and pharmaceutical research. This compound, characterized by its tert-butoxy substituent on a phenyl ring attached to a methanol moiety, has garnered attention due to its versatile applications in synthetic chemistry and potential roles in drug development.

The structure of [4-(tert-butoxy)phenyl]methanol imparts unique chemical properties that make it valuable in various chemical transformations. The presence of the tert-butoxy group enhances the stability of the molecule, making it useful in reactions that require resistance to hydrolysis and oxidation. This stability is particularly advantageous in pharmaceutical synthesis, where maintaining structural integrity under harsh reaction conditions is crucial.

Recent research has highlighted the utility of [4-(tert-butoxy)phenyl]methanol in the synthesis of pharmaceutical intermediates. Its aromatic ring and hydroxyl functionality provide multiple sites for further chemical modifications, enabling the creation of complex molecules. For instance, studies have demonstrated its role in the preparation of nonsteroidal anti-inflammatory drug (NSAID) analogs, where the tert-butoxy group serves as a protective moiety during synthetic steps.

In addition to its applications in drug synthesis, [4-(tert-butoxy)phenyl]methanol has been explored in the development of organic electronics. The compound's ability to form stable radicals and its electron-donating properties make it suitable for use in organic light-emitting diodes (OLEDs) and other electronic materials. Researchers have reported its incorporation into conjugated polymers, which are essential components in advanced electronic devices.

The pharmaceutical industry has shown particular interest in [4-(tert-butoxy)phenyl]methanol due to its potential as a prodrug or an intermediate in the synthesis of bioactive molecules. Its structural features allow for selective modifications, enabling the development of drugs with enhanced bioavailability or targeted delivery systems. For example, derivatives of this compound have been investigated for their role in modulating enzyme activity and interacting with biological receptors.

Moreover, [4-(tert-butoxy)phenyl]methanol has found applications in chemical sensors and analytical chemistry. Its unique reactivity and spectral properties make it useful for detecting trace amounts of analytes in environmental and biological samples. Researchers have developed sensor arrays based on this compound that can selectively identify various chemicals, contributing to advancements in fields such as environmental monitoring and medical diagnostics.

The synthesis of [4-(tert-butoxy)phenyl]methanol typically involves bromination of an aromatic precursor followed by reaction with a tert-butanol derivative. This method leverages well-established organic reactions, ensuring high yield and purity. Recent improvements in synthetic techniques have further optimized the process, making it more efficient and scalable for industrial applications.

In conclusion, [4-(tert-butoxy)phenyl]methanol (CAS No. 51503-08-3) is a multifaceted compound with significant potential across multiple domains of chemistry and pharmaceutical research. Its unique structure and reactivity make it invaluable for synthesizing complex molecules, developing advanced materials, and creating innovative diagnostic tools. As research continues to uncover new applications for this compound, its importance is likely to grow even further.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:51503-08-3)[4-(tert-butoxy)phenyl]methanol
A871261
Purity:99%/99%/99%
Quantity:1g/5g/10g
Price ($):152.0/248.0/368.0
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