• 1. An apparatus for testing water by measurement of its electrical conductivity
  Analyst, 1912,37, 538-543
• 2. An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment?
  Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
• 3. An approach for correlating the structural and electrical properties of Zr4+-modified SrBi4Ti4O15/SBT ceramic
  Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo Panigrahi RSC Adv., 2017,7, 16319-16331
• 4. An Aptamer Bio-barCode (ABC) assay using SPR, RNase H, and probes with RNA and gold-nanorods for anti-cancer drug screening
  Chengbin Yang,Hing Lun Tsang,Pui Man Lau,Ken-Tye Yong,Ho Pui Ho,Siu Kai Kong Analyst, 2017,142, 3579-3587
• 5. An insight into the origin of room-temperature ferromagnetism in SnO2 and Mn-doped SnO2 quantum dots: an experimental and DFT approach?
  Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Xanthophylls
• Other Chemical Reagents

Canthaxanthin (CAS No. 514-78-3): A Comprehensive Overview

Canthaxanthin (CAS No. 514-78-3) is a naturally occurring carotenoid that has gained significant attention in the fields of nutrition, cosmetics, and pharmaceuticals due to its unique properties and potential health benefits. This comprehensive overview aims to provide a detailed understanding of canthaxanthin, including its chemical structure, biological functions, applications, and recent research findings.

Chemical Structure and Properties

Canthaxanthin is a xanthophyll carotenoid with the molecular formula C₄₀H₅₂O₂. It is a yellow to orange crystalline powder that is insoluble in water but soluble in organic solvents such as ethanol and chloroform. The chemical structure of canthaxanthin consists of a conjugated polyene chain with two hydroxyl groups at the terminal ends, which contribute to its antioxidant properties. The presence of these hydroxyl groups also enhances its stability and bioavailability.

Biological Functions and Health Benefits

Canthaxanthin is known for its potent antioxidant activity, which helps protect cells from oxidative damage caused by free radicals. This property makes it valuable in preventing various diseases associated with oxidative stress, such as cardiovascular disease, cancer, and neurodegenerative disorders. Recent studies have shown that canthaxanthin can also modulate immune responses and reduce inflammation, further contributing to its health benefits.

In addition to its antioxidant properties, canthaxanthin has been studied for its potential role in skin health. It is commonly used in cosmetic products due to its ability to improve skin color and texture by promoting melanin production. Research has also indicated that canthaxanthin can protect the skin from UV-induced damage, making it a valuable ingredient in sunscreens and other skincare products.

Clinical Applications and Research Findings

The use of canthaxanthin in clinical settings has been explored in various studies. One notable application is in the treatment of macular degeneration, a leading cause of vision loss in older adults. Studies have shown that supplementation with canthaxanthin can improve visual acuity and slow the progression of macular degeneration by protecting retinal cells from oxidative damage.

In the field of nutrition, canthaxanthin has been investigated for its potential as a dietary supplement. Clinical trials have demonstrated that regular consumption of foods rich in canthaxanthin, such as salmon and trout, can enhance overall health and reduce the risk of chronic diseases. Additionally, research has suggested that canthaxanthin may have anti-obesity effects by regulating lipid metabolism and reducing fat accumulation.

Safety and Regulatory Considerations

The safety profile of canthaxanthin has been extensively evaluated. It is generally recognized as safe (GRAS) by regulatory agencies such as the U.S. Food and Drug Administration (FDA) when used within recommended dosages. However, excessive intake can lead to side effects such as canthaxanthin retinopathy, characterized by yellowish deposits in the retina. Therefore, it is important to follow guidelines and consult healthcare professionals before using products containing high concentrations of canthaxanthin.

FUTURE DIRECTIONS AND CONCLUSIONS

The future of research on < strong >canthaxanthin< / strong > is promising, with ongoing studies exploring its potential applications in various fields. Advances in biotechnology and synthetic methods are expected to enhance the production and availability of this valuable compound. Additionally, further clinical trials are needed to fully understand the long-term effects and optimal dosages of canthaxanthin< / strong > for different health conditions.

• 84696-84-4(2-Cyclohexen-1-one,3-(1,3-butadien-1-yl)-2,4,4-trimethyl-)
• 27185-77-9(2-Cyclohexen-1-one,2,4,4-trimethyl-3-(3-oxo-1-buten-1-yl)-)
• 66362-91-2((+/-)-(3,4,4a,5,6,7-Hexahydro-4a,8-dimethyl-2-naphthalenyl)-1-ethanone)
• 23665-63-6((4As)-1,4a-dimethyl-7-propan-2-yl-3,4,5,6-tetrahydronaphthalen-2-one)
• 88943-03-7(2-Cyclohexen-1-one,2,4,4-trimethyl-3-(3-methyl-7-oxo-1,3,5-octatrienyl)-)
• 16840-81-6(3',4'-Didehydro-beta,(-caroten-4-one)
• 33532-44-4(4-Keto Retinal)
• 432-68-8(Echinenone (Technical Grade))
• 29790-29-2(2-Cyclohexen-1-one,2,4,4-trimethyl-3-[(1E)-3-oxo-1-buten-1-yl]-)
• 54650-04-3((1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-1,18-bis(2,6,6-trimethyl-1-cyclohexenyl)octadeca-1,3,5,7,9,11,13,15,17-nonaene; 2,4,4-trimethyl-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethyl-3-oxo-1-cyclohexenyl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-2-en-1-one)