Cas no 51382-91-3 (Norchlorprothixene)

Norchlorprothixene is a pharmaceutical compound belonging to the thioxanthene class, primarily used as an antipsychotic agent. It exhibits potent antipsychotic activity with minimal sedative effects, making it suitable for treating schizophrenia. The compound demonstrates high selectivity for dopamine D2 receptors, contributing to its efficacy. Additionally, its favorable pharmacokinetic profile ensures consistent therapeutic levels with once-daily dosing.
Norchlorprothixene structure
Norchlorprothixene structure
Product Name:Norchlorprothixene
CAS No:51382-91-3
MF:C17H16ClNS
MW:301.83364200592
CID:362381
PubChem ID:92029501
Update Time:2025-10-15

Norchlorprothixene Chemical and Physical Properties

Names and Identifiers

    • 1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N-methyl-, (Z)-
    • Norchlorprothixene
    • 3-(2-chlorothioxanthen-9-ylidene)-N-methylpropan-1-amine
    • Demethylchlorprothixene
    • (Z)-N-Methyl-3-(2-chloro-9H-thioxanthene-9-ylidene)-1-propanamine
    • Q27264865
    • J730.383A
    • UNII-6G94400Q0T
    • 51382-91-3
    • (Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N-methylpropan-1-amine
    • (3Z)-3-(2-chlorothioxanthen-9-ylidene)-N-methylpropan-1-amine
    • (3Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)-N-methyl-1-propanamine
    • AKOS040751525
    • CHLORPROTHIXENE HYDROCHLORIDE IMPURITY C [EP IMPURITY]
    • 1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N-methyl-, (3Z)-
    • 6G94400Q0T
    • (3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N-methylpropan-1-amine
    • 9H-Thioxanthene, 1-Propanamine Deriv.; Demethylchlorprothixene; N-Monodemethylchlorprothixene; (Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)-N-methyl-1-propanamine; (3Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)-N-methyl-1-propanamine;
    • CHLORPROTHIXENE_met007
    • Inchi: 1S/C17H16ClNS/c1-19-10-4-6-13-14-5-2-3-7-16(14)20-17-9-8-12(18)11-15(13)17/h2-3,5-9,11,19H,4,10H2,1H3/b13-6-
    • InChI Key: MFNIWJBWDRDXPK-MLPAPPSSSA-N
    • SMILES: ClC1C=CC2=C(C=1)/C(=C\CCNC)/C1C=CC=CC=1S2

Computed Properties

  • Exact Mass: 301.06938
  • Monoisotopic Mass: 301.0691984g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 20
  • Rotatable Bond Count: 3
  • Complexity: 357
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 4.7
  • Topological Polar Surface Area: 37.3?2

Experimental Properties

  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 443.2±45.0 °C at 760 mmHg
  • Flash Point: 221.8±28.7 °C
  • PSA: 12.03
  • Vapor Pressure: 0.0±1.1 mmHg at 25°C

Norchlorprothixene Security Information

Norchlorprothixene Pricemore >>

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