• 1. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
• 2. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
• 3. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 4. Empowering microfluidics by micro-3D printing and solution-based mineral coating?
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• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides
• Solvents and Organic Chemicals Organic Compounds

Comprehensive Overview of 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine (CAS No. 51094-17-8): Properties, Applications, and Research Insights

5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine (CAS No. 51094-17-8) is a highly specialized porphyrin derivative with significant scientific and industrial relevance. This compound belongs to the class of tetraphenylporphyrins, characterized by a macrocyclic structure with four hydroxyphenyl substituents. Its unique molecular architecture, combining a porphine core with phenolic functional groups, makes it a versatile building block for advanced materials, photosensitizers, and molecular sensors.

The growing interest in porphyrin-based compounds like 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine is driven by their exceptional photophysical properties. Researchers frequently search for "porphyrin applications in photodynamic therapy" or "tetraphenylporphyrin synthesis methods," reflecting its importance in biomedical and materials science. The compound's ability to absorb visible light and generate reactive oxygen species (ROS) positions it as a candidate for cancer treatment and antimicrobial coatings—topics trending in nanotechnology forums.

From a structural perspective, the hydroxyphenyl groups in CAS No. 51094-17-8 enable facile chemical modifications, a feature often queried as "functionalization of porphyrin derivatives" in academic databases. This adaptability allows covalent conjugation with polymers, nanoparticles, or biomolecules, addressing current demands for "hybrid materials for renewable energy"—a hot topic aligned with global sustainability goals. Recent studies highlight its role in organic photovoltaics and hydrogen evolution catalysts, correlating with the surge in "green chemistry porphyrins" search volumes.

Analytical applications of 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine are another focal point. Its distinct colorimetric response to pH changes and metal ions answers frequent queries about "porphyrin-based chemical sensors." The compound's chelating properties are exploited in environmental monitoring, particularly in detecting heavy metals—a subject gaining traction due to increased regulatory scrutiny on water quality standards worldwide.

In pharmaceutical research, this porphyrin derivative is investigated for "drug delivery systems" (a high-volume keyword) owing to its biocompatibility and tunable hydrophilicity. The phenolic hydroxyl groups facilitate the formation of nanocarriers with enhanced tumor-targeting capabilities, a strategy frequently discussed in peer-reviewed journals on nanomedicine. Such applications resonate with the public's growing interest in "next-generation cancer therapies" and "precision medicine."

Synthetic accessibility is another advantage of CAS No. 51094-17-8, with optimized protocols available for scalable production—addressing the industrial need for "cost-effective porphyrin synthesis." The compound serves as a precursor for advanced metal-organic frameworks (MOFs), a trending topic in materials science circles. Its thermal stability and π-conjugation make it suitable for designing porous materials for gas storage or separation technologies.

Emerging studies explore the compound's role in artificial photosynthesis systems, responding to the global push for "carbon-neutral technologies." The porphine core mimics chlorophyll's light-harvesting properties, making it relevant for "bio-inspired energy solutions"—a phrase with rising search engine visibility. This aligns with recent breakthroughs in solar fuel generation reported at international conferences on sustainable chemistry.

Quality control aspects of 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine are critical for reproducibility, as indicated by laboratory queries about "HPLC analysis of porphyrins." Standardized characterization techniques including mass spectrometry and NMR spectroscopy ensure batch-to-batch consistency, particularly important for biomedical applications where purity thresholds exceed 98%.

The compound's structure-activity relationships continue to inspire computational chemistry studies, evidenced by academic searches for "DFT calculations on porphyrinoids." Theoretical modeling predicts its electronic transitions and redox potentials—data essential for designing optoelectronic devices or catalytic systems. Such interdisciplinary applications demonstrate why CAS No. 51094-17-8 remains a staple in high-impact research publications.

Looking ahead, the integration of 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine into smart materials represents an innovative frontier. Its stimuli-responsive behavior caters to the demand for "adaptive coatings" and "self-healing polymers," topics dominating materials engineering discourse. As industries seek eco-friendly alternatives, this compound's derivatization potential positions it favorably within the "green materials revolution"—a movement reshaping manufacturing paradigms globally.

• 22112-79-4(Tetra(3-hydroxyphenyl)porphyrin)
• 145764-54-1(5,10,15,20-Tetrakis(3,5-dihydroxyphenyl)porphyrin)
• 57412-08-5(Phenol, 4-[10,15,20-tris(4-methylphenyl)-21H,23H-porphin-5-yl]-)
• 147859-70-9(Phenol, 4,4'-(10,20-diphenyl-21H,23H-porphine-5,15-diyl)bis-)
• 502761-92-4(1,2-BENZENEDIOL, 4,4'-(10,20-DIPHENYL-21H,23H-PORPHINE-5,15-DIYL)BIS-)
• 87377-51-3(3-[(1Z,4Z,9Z,15Z)-10,15,20-triphenyl-21,23-dihydroporphyrin-5-yl]phenol)
• 127801-02-9
• 87345-22-0(4-(10,15,20-Triphenyl-5-porphyrinyl)phenol)
• 202268-34-6(4,4'-(15,20-Diphenylporphyrin-5,10-diyl)diphenol)
• 57412-06-3(PHENOL, 3-[10,15,20-TRIS(4-METHYLPHENYL)-21H,23H-PORPHIN-5-YL]-)