Cas no 50891-33-3 (Benzamide,5-amino-2-(1-piperidinyl)-)

Benzamide,5-amino-2-(1-piperidinyl)- is a substituted benzamide derivative featuring an amino group at the 5-position and a piperidinyl moiety at the 2-position of the benzene ring. This structural configuration imparts potential utility in medicinal chemistry and pharmaceutical research, particularly as an intermediate in the synthesis of bioactive compounds. The presence of both amino and piperidinyl groups enhances its reactivity and binding affinity, making it suitable for applications in drug discovery and development. Its well-defined molecular structure allows for precise modifications, facilitating the exploration of structure-activity relationships. The compound is typically characterized by high purity and stability, ensuring reliable performance in synthetic applications.
Benzamide,5-amino-2-(1-piperidinyl)- structure
50891-33-3 structure
Product Name:Benzamide,5-amino-2-(1-piperidinyl)-
CAS No:50891-33-3
MF:C12H17N3O
MW:219.282882452011
CID:386560
PubChem ID:845164
Update Time:2025-06-13

Benzamide,5-amino-2-(1-piperidinyl)- Chemical and Physical Properties

Names and Identifiers

    • Benzamide,5-amino-2-(1-piperidinyl)-
    • 5-amino-2-(1-piperidinyl)Benzamide
    • 5-amino-2-piperidin-1-ylbenzamide
    • 5-Amino-2-piperidin-1-yl-benzamide
    • DTXSID70357134
    • SDCCGMLS-0064977.P001
    • HMS1553C21
    • 5-Amino-2-piperidin-1-yl-benzamide, AldrichCPR
    • VS-09474
    • HMS2645H12
    • AKOS000345389
    • FT-0677083
    • Oprea1_425851
    • 5-amino-2-(piperidin-1-yl)benzamide
    • CHEMBL1533712
    • SB44144
    • BB 0254381
    • CS-0323023
    • TimTec1_006753
    • Oprea1_628966
    • 50891-33-3
    • SCHEMBL17774829
    • SMR000281400
    • Cambridge id 7268696
    • MLS000711633
    • MDL： MFCD03042683
    • Inchi： 1S/C12H17N3O/c13-9-4-5-11(10(8-9)12(14)16)15-6-2-1-3-7-15/h4-5,8H,1-3,6-7,13H2,(H2,14,16)
    • InChI Key： LUAYPIWXMDEQHJ-UHFFFAOYSA-N
    • SMILES： O=C(C1C=C(C=CC=1N1CCCCC1)N)N

Computed Properties

  • Exact Mass: 219.13700
  • Monoisotopic Mass: 219.137162174g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 2
  • Complexity: 251
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.1
  • Topological Polar Surface Area: 72.4?2

Experimental Properties

  • PSA: 72.35000
  • LogP: 2.70450

Benzamide,5-amino-2-(1-piperidinyl)- Security Information

  • Hazard Category Code： 36
  • Safety Instruction： 26
  • Hazardous Material Identification： Xi
  • HazardClass：IRRITANT

Benzamide,5-amino-2-(1-piperidinyl)- Customs Data

  • HS CODE：2933399090
  • Customs Data：

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Benzamide,5-amino-2-(1-piperidinyl)- Pricemore >>

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Benzamide,5-amino-2-(1-piperidinyl)- Related Literature

Additional information on Benzamide,5-amino-2-(1-piperidinyl)-

Comprehensive Analysis of Benzamide,5-amino-2-(1-piperidinyl)- (CAS No. 50891-33-3)

Benzamide,5-amino-2-(1-piperidinyl)-, with the CAS number 50891-33-3, is a specialized organic compound that has garnered significant attention in pharmaceutical and biochemical research. This compound belongs to the benzamide derivatives family, known for their diverse biological activities and applications in drug development. The presence of both amino and piperidinyl functional groups in its structure makes it a versatile intermediate for synthesizing more complex molecules.

In recent years, the demand for 5-amino-2-(1-piperidinyl)benzamide has increased due to its potential role in targeting neurological and metabolic disorders. Researchers are particularly interested in its structure-activity relationship (SAR), which could unlock new therapeutic avenues. The compound's molecular formula and weight are critical for computational chemists and pharmacologists working on drug design and virtual screening.

One of the most searched questions related to this compound is: "What are the applications of Benzamide,5-amino-2-(1-piperidinyl)- in medicine?" Preliminary studies suggest its derivatives may act as enzyme inhibitors or receptor modulators, particularly in pathways associated with inflammation and neurodegeneration. However, further clinical validation is required to confirm these hypotheses.

Another trending topic is the synthetic routes for 50891-33-3. Organic chemists often explore green chemistry approaches to optimize its production, minimizing waste and energy consumption. The compound's solubility and stability under various conditions are also frequently discussed in forums and research papers.

From an industrial perspective, Benzamide,5-amino-2-(1-piperidinyl)- is valued for its role in high-throughput screening (HTS) libraries. Its pharmacophore features align with targets like G-protein-coupled receptors (GPCRs), making it a candidate for lead optimization in drug discovery pipelines.

Environmental and safety considerations are equally important. While not classified as hazardous, proper handling protocols for CAS 50891-33-3 are essential to ensure workplace safety. Researchers emphasize the need for material safety data sheets (MSDS) compliance during storage and transportation.

In summary, Benzamide,5-amino-2-(1-piperidinyl)- represents a promising scaffold in modern chemistry. Its multifunctional design and broad applicability continue to inspire innovations across pharmaceuticals, agrochemicals, and material science. As studies progress, this compound may soon transition from labs to commercial therapeutics, addressing unmet medical needs.

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