Cas no 5089-72-5 (N-(2-Aminoethyl)-3-aminopropyltriethoxysilane)

N-(2-Aminoethyl)-3-aminopropyltriethoxysilane is a bifunctional organosilane coupling agent featuring both primary and secondary amine groups, along with hydrolyzable triethoxysilyl functionality. This compound is widely utilized to enhance adhesion between organic polymers and inorganic substrates, such as glass, metals, or minerals. Its dual-reactive groups enable covalent bonding with surfaces while promoting compatibility with resin matrices, improving mechanical properties in composites. The ethoxy groups facilitate hydrolysis and condensation, forming stable siloxane networks. Applications include coatings, adhesives, and sealants, where improved interfacial strength and moisture resistance are critical. The compound's amine functionality also allows for further chemical modifications, making it valuable in advanced material synthesis.
N-(2-Aminoethyl)-3-aminopropyltriethoxysilane structure
5089-72-5 structure
Product Name:N-(2-Aminoethyl)-3-aminopropyltriethoxysilane
CAS No:5089-72-5
MF:C11H28N2O3Si
MW:264.437124252319
MDL:MFCD00138097
CID:45525
PubChem ID:87559682
Update Time:2025-10-30

N-(2-Aminoethyl)-3-aminopropyltriethoxysilane Chemical and Physical Properties

Names and Identifiers

    • N1-(3-(Triethoxysilyl)propyl)ethane-1,2-diamine
    • N-(3-Triethoxysilylpropyl)ethylenediamine
    • N-(2-AMINOETHYL)-3-AMINOPROPYLTRIETHOXYSILANE
    • 2-Ethanediamine,N-[3-(triethoxysilyl)propyl]-1
    • AMINOETHYL AMINOPROPYL TRIETHOXYSILANE
    • N-beta-(aminoethyl)-gamma-aminopropyltriethoxysilane
    • N-Beta-(Aminoethyl)-3-Aminopropyltriethoxysilane
    • 3-(2-Aminoethyl)-3-aminopropyltriethoxysilane
    • 1,2-Ethanediamine, N-3-(triethoxysilyl)propyl-
    • 3-(2-aminoethylamino)propyltriethoxysilane
    • 2-Aminoethyl-3-aminopropyltriethoxysilane
    • N-[3-(triethoxysilyl)propyl]-1,2-ethanediamine,
    • N-(2-AMINOETHYL)-3-(TRIETHOXYSILYL)PROPYLAMINE
    • N-(β-aminoethyl)- γ-aminopropytriethoxysilane
    • Silane Coupling Agent Si-910
    • n-β-ethyl-γ-aminopropyl triethoxy silane
    • 3-(2-Aminoethyl)-Aminopropyltriethoxysilane
    • N'-(3-triethoxysilylpropyl)ethane-1,2-diamine
    • Aminoethylaminopropyltriethoxysilane
    • N-(3-(Triethoxysilyl)propyl)ethylenediamine
    • 1,2-Ethanediamine, N-[3-(triethoxysilyl)propyl]-
    • 1,2-Ethanediamine, N1-(3-(triethoxysilyl)propyl)-
    • 1,2-Ethanediamine, N1-[3-(triethoxysilyl)propyl]-
    • C11H28N2O3Si
    • INJVFBCDVXYHGQ-UHFFFA
    • FT-0629098
    • EINECS 225-806-1
    • NS00045834
    • Ethylenediamine, N-[3-(triethoxysilyl)propyl]-
    • 5089-72-5
    • AKOS008901326
    • S00610
    • CS-0205390
    • D88485
    • N1-[3-(Triethoxysilyl)propyl]-1,2-ethanediamine
    • 191718-72-6
    • MFCD00138097
    • (2-aminoethyl)[3-(triethoxysilyl)propyl]amine
    • INJVFBCDVXYHGQ-UHFFFAOYSA-N
    • DTXSID4074647
    • N-2-(Aminoethyl)-3-AminoPropyltriethoxysilane
    • N-(3-(triethoxysilyl)propyl)ethane-1,2-diamine
    • HZ4EXB3ESF
    • SCHEMBL18766
    • N-(2-AMINOETHYL)-3-AMINOPROPYLTRIETHOXYSILANE, 92%
    • DB-030075
    • A1923
    • N-(2-Aminoethyl)-3-aminopropyltriethoxysilane
    • MDL: MFCD00138097
    • Inchi: 1S/C11H28N2O3Si/c1-4-14-17(15-5-2,16-6-3)11-7-9-13-10-8-12/h13H,4-12H2,1-3H3
    • InChI Key: INJVFBCDVXYHGQ-UHFFFAOYSA-N
    • SMILES: [Si](CCCNCCN)(OCC)(OCC)OCC

Computed Properties

  • Exact Mass: 264.18700
  • Monoisotopic Mass: 264.187
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 12
  • Complexity: 156
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 65.7

Experimental Properties

  • Color/Form: Uncertain
  • Density: 0.970
  • Melting Point: 135 oC (5 mmHg)
  • Boiling Point: 156°C/15mmHg(lit.)
  • Flash Point: 123°C
  • Refractive Index: 1.438
  • PSA: 65.74000
  • LogP: 2.06440
  • Sensitiveness: Sensitive to humidity
  • Solubility: Uncertain

N-(2-Aminoethyl)-3-aminopropyltriethoxysilane Security Information

N-(2-Aminoethyl)-3-aminopropyltriethoxysilane Customs Data

  • HS CODE:2931900090
  • Customs Data:

    China Customs Code:

    2931900090

    Overview:

    2931900090. Other organic-Inorganic compound. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods). MFN tariff:6.5%. general tariff:30.0%

    Summary:

    2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

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N-(2-Aminoethyl)-3-aminopropyltriethoxysilane Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:5089-72-5)N-(2-Aminoethyl)-3-aminopropyltriethoxysilane
Order Number:A828342
Stock Status:in Stock
Quantity:1kg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 05:27
Price ($):190.0
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:5089-72-5)N-(3-Triethoxysilylpropyl)ethylenediamine
Order Number:sfd5832
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:5089-72-5)Silane coupler KH-791
Order Number:LE4417;LE2473843
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:45
Price ($):discuss personally

Additional information on N-(2-Aminoethyl)-3-aminopropyltriethoxysilane

Recent Advances in the Application of N-(2-Aminoethyl)-3-aminopropyltriethoxysilane (CAS: 5089-72-5) in Chemical Biology and Pharmaceutical Research

N-(2-Aminoethyl)-3-aminopropyltriethoxysilane (CAS: 5089-72-5) is a bifunctional organosilane compound that has garnered significant attention in chemical biology and pharmaceutical research due to its unique properties. This compound serves as a versatile linker for surface modification, drug delivery systems, and biomaterial functionalization. Recent studies have explored its applications in enhancing the biocompatibility of medical devices, improving drug targeting, and facilitating the immobilization of biomolecules. The presence of both amino and triethoxysilane groups allows for covalent bonding with various substrates, making it an invaluable tool in interdisciplinary research.

One of the most notable advancements in the use of N-(2-Aminoethyl)-3-aminopropyltriethoxysilane is its role in the development of targeted drug delivery systems. Researchers have successfully utilized this compound to functionalize nanoparticles, enabling precise delivery of therapeutic agents to specific tissues or cells. For instance, a 2023 study demonstrated the efficacy of silane-modified nanoparticles in delivering anticancer drugs to tumor sites with minimal off-target effects. The amino groups on the silane molecule facilitated the conjugation of targeting ligands, while the triethoxysilane groups ensured stable attachment to the nanoparticle surface.

In addition to drug delivery, this compound has shown promise in the field of biosensors. A recent publication highlighted its use in the immobilization of enzymes on electrode surfaces, significantly improving the sensitivity and stability of electrochemical biosensors. The study reported that the silane layer formed by N-(2-Aminoethyl)-3-aminopropyltriethoxysilane provided a robust platform for enzyme attachment, while maintaining their catalytic activity. This breakthrough has opened new avenues for the development of high-performance diagnostic tools.

Another emerging application of N-(2-Aminoethyl)-3-aminopropyltriethoxysilane is in tissue engineering. Researchers have employed this compound to modify scaffold surfaces, enhancing cell adhesion and proliferation. A 2024 study demonstrated that silane-treated scaffolds promoted the growth of mesenchymal stem cells, suggesting potential for regenerative medicine applications. The amino groups on the silane molecule were found to interact favorably with cell surface receptors, while the siloxane network improved the mechanical stability of the scaffolds.

Despite these advancements, challenges remain in the optimization of N-(2-Aminoethyl)-3-aminopropyltriethoxysilane-based systems. Recent research has focused on addressing issues such as batch-to-batch variability, long-term stability, and potential cytotoxicity. A 2023 review article emphasized the need for standardized protocols in silane modification to ensure reproducibility across studies. Additionally, ongoing investigations are exploring the structure-activity relationship of this compound to further refine its applications in pharmaceutical formulations.

Looking ahead, the versatility of N-(2-Aminoethyl)-3-aminopropyltriethoxysilane (CAS: 5089-72-5) continues to inspire innovative research across multiple disciplines. Its unique chemical properties make it a valuable asset in the development of next-generation biomedical technologies. Future studies are expected to explore its potential in gene delivery, antimicrobial coatings, and smart materials, further expanding its impact on the chemical biology and pharmaceutical fields.

Recommended suppliers
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Suzhou Senfeida Chemical Co., Ltd
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