Cas no 503612-47-3 (Apixaban)

Apixaban is an oral anticoagulant that provides rapid and predictable inhibition of Factor Xa, thereby reducing the risk of thromboembolic events without significant impact on coagulation parameters in therapeutic range bleeding times. Its stable dosing regimen and minimal food interactions enhance its clinical utility for managing venous thrombosis prevention and treatment.

Apixaban structure

Product Name:Apixaban

CAS No:503612-47-3

MF:C₂₅H₂₅N₅O₄

MW:459.497105360031

MDL:MFCD11977295

CID:68342

PubChem ID:10182969

Update Time:2025-08-26

Apixaban Chemical and Physical Properties

Names and Identifiers

- Apixaban
- BMS562247
- Apixaban, BMS 562247-01
- 1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-
- 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
- BMS 562247-01
- 1-(4-Methoxy-phenyl)-7-oxo-6-[4-(2-oxo-piperidin-1-yl)-phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid aMide
- 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4, 5-dihydropyrazolo[3,4-c]pyridine-3-carboxaMide
- Nilotinib and its interMediate
- Apixaban,BMS562247
- BMS-562247-01
- Eliquis
- UNII-3Z9Y7UWC1J
- GG2
- NCGC00346555-08
- QNZCBYKSOIHPEH-UHFFFAOYSA-N
- BCP9000310
- 1H-Pyrazolo(3,4-c)pyridine-3-carboxamide, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-
- 1H-Pyrazolo(3,4-c)pyridine-3-carboxamide,4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-
- EX-A048
- 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-4,5,6,7-tetrahydro-1h-pyrazolo[3,4-c]pyridine-3-carboxamide
- Apixaban,BMS-562247-01
- HSDB 8223
- 503612-47-3
- BMS 562247
- 503612-47-3, Eliquis,
- C25H25N5O4
- PB10976
- MFCD11977295
- CHEMBL231779
- Apixaban 13CD3
- 1H-PYRAZOLO(3,4-C)PYRIDINE-3-CARBOXAMIDE, 4,5,6,7-TETRAHYDRO-1-( 4-METHOXYPHENYL)-7-OXO-6-(4-(2-OXO-1-PIPERIDINYL)PHENYL)-
- BMS-562247
- s1593
- BCP02451
- APIXABAN [WHO-DD]
- APIXABAN (MART.)
- 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxamide
- Apixaban (JAN/USAN/INN)
- DTXCID60387324
- APIXABAN [VANDF]
- BM164185
- Apixaban [USAN:INN:JAN]
- 1-(4-METHOXYPHENYL)-7-OXO-6-(4-(2-OXOPIPERIDIN-1-YL)PHENYI)-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO(3,4-C)PYRIDINE-3-CARBOXAMIDE
- CHEBI:72296
- APIXABAN [MI]
- Apixaban- Bio-X
- BDBM19023
- APIXABAN [JAN]
- AC-26301
- Q414462
- BCPP000396
- BMS562247-01
- 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide
- APIXABAN [MART.]
- HMS3655O07
- Z195110238
- NCGC00346555-02
- NCGC00346555-05
- APIXABAN [INN]
- 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide?BMS-562247; BMS-562247-01
- SW220177-1
- NCGC00346555-01
- ME-0152
- SY097159
- 2p16
- ELIQUIS30-Day Starter Pack
- GTPL6390
- 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo piperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
- J-200194
- AMY1826
- Apixaban(BMS-562247-01)
- AB01565766_02
- 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
- 3Z9Y7UWC1J
- 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo(3,4-c)pyridine-3-carboxamide
- CS-0401
- DTXSID80436500
- NSC-784102
- 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-3-carboxamide
- B01AF02
- APIXABAN [ORANGE BOOK]
- FT-0686944
- Apixaban [USAN]
- 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-
- Eliquis (TN)
- HY-50667
- 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
- SMR004676529
- apixabanum
- AKOS005146204
- AR-270/43507990
- NS00014946
- NSC784102
- DB06605
- Apixaban (BMS 562247-01)
- 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo(3,4c)pyridine-3-carboxamide
- CCG-229675
- SCHEMBL118023
- MLS006010026
- APIXABAN [EMA EPAR]
- D03213
- BRD-K67121414-001-03-3
- BRD-K67121414-001-02-5
- Apixaban (BMS 562247-01)?
- MDL： MFCD11977295
- Inchi： 1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32)
- InChI Key： QNZCBYKSOIHPEH-UHFFFAOYSA-N
- SMILES： O=C1C2=C(C(C(N)=O)=NN2C2C=CC(=CC=2)OC)CCN1C1C=CC(=CC=1)N1C(CCCC1)=O

Computed Properties

Exact Mass: 459.19100
Monoisotopic Mass: 459.191
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 9
Heavy Atom Count: 34
Rotatable Bond Count: 5
Complexity: 777
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 111A^2
XLogP3: 2.2

Experimental Properties

Color/Form: No data avaiable
Density: 1.42
Melting Point: 326.53
Boiling Point: 770.5±60.0 °C at 760 mmHg
Flash Point: 419.8±32.9 °C
Refractive Index: 1.705
Solubility: 生物體外In Vitro:DMSO溶解度14.25 mg/mL(31.01 mM;Need ultrasonic and warming需要超聲波和加熱)H2O : < 0.1 mg/mL(insoluble)
PSA: 110.76000
LogP: 3.52990
Vapor Pressure: 0.0±2.6 mmHg at 25°C

Apixaban Security Information

Signal Word：Warning
Hazard Statement： H302-H315-H319-H332-H335
Warning Statement： P261-P280-P305+P351+P338
Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month

Apixaban Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	A126046-1g	Apixaban	503612-47-3	≥99%	1g	￥291.90	2023-09-04
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	A126046-50mg	Apixaban	503612-47-3	≥99%	50mg	￥61.90	2023-09-04
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	A126046-250mg	Apixaban	503612-47-3	≥99%	250mg	￥103.90	2023-09-04
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	A126046-10mg	Apixaban	503612-47-3	≥99%	10mg	￥31.90	2023-09-04
S e l l e c k ZHONG GUO	S1593-10mM (1mL in DMSO)	Apixaban	503612-47-3	99.98%	10mM (1mL in DMSO)	￥3449.65	2023-09-16
S e l l e c k ZHONG GUO	S1593-10mg	Apixaban	503612-47-3	99.98%	10mg	￥2607.69	2025-07-14
S e l l e c k ZHONG GUO	S1593-50mg	Apixaban	503612-47-3	99.98%	50mg	￥7940.17	2025-07-14
S e l l e c k ZHONG GUO	S1593-200mg	Apixaban	503612-47-3	99.98%	200mg	￥15700	2025-07-14
Chemenu	CM328450-5g	1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide	503612-47-3	95%+	5g	$165	2021-08-18
Chemenu	CM328450-25g	1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide	503612-47-3	95%+	25g	$565	2021-08-18

Apixaban Suppliers

Suzhou Senfeida Chemical Co., Ltd

Gold Member

Audited Supplier

(CAS:503612-47-3)Apixaban

Order Number:sfd11273

Stock Status:in Stock

Quantity:200kg

Purity:99.9%

Pricing Information Last Updated:Friday, 19 July 2024 14:35

Price ($):discuss personally

Email:[email protected]

Product Official Link

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:503612-47-3)apixaban

Order Number:LE1711;LE25874748

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 11:41

Price ($):discuss personally

Email:[email protected]

Apixaban Spectrogram

1H NMR

300 MHz

DMSO

MS-MS

13C NMR

Apixaban Related Literature

1. A liquid chromatography-tandem mass spectrometry method for the determination of apixaban in human plasma and its application to pharmacokinetics studies in the Indian population

Khurshid Shaikh,Ashish Mungantiwar,Supriya Halde,Nancy Pandita Anal. Methods 2021 13 3693
2. Sensitive validated voltammetric determination of apixaban using a multi-walled carbon nanotube-modified carbon paste electrode: application to a drug product and biological sample

Mohamed Rizk,Maha A. Sultan,Elham A. Taha,Ali K. Attia,Youmna M. Abdallah Anal. Methods 2017 9 2523
3. A comprehensive study of apixaban's degradation pathways under stress conditions using liquid chromatography coupled to multistage mass spectrometry

Philippe-Henri Secrétan,Hassane Sadou-Yayé,Caroline Aymes-Chodur,Mélisande Bernard,Audrey Solgadi,Fatma Amrani,Najet Yagoubi,Bernard Do RSC Adv. 2015 5 35586
4. Point of care whole blood microfluidics for detecting and managing thrombotic and bleeding risks

Scott L. Diamond,Jason M. Rossi Lab Chip 2021 21 3667
5. A ratiometric electrochemical probe for the quantification of apixaban in unprocessed plasma samples using carbon aerogel/BFO modified glassy carbon electrodes

Payam Shahbazi-Derakhshi,Mohammad Abbasi,Amirhossein Akbarzadeh,Ahad Mokhtarzadeh,Hamid Hosseinpour,Jafar Soleymani RSC Adv. 2023 13 21432

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Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Piperidines Phenylpiperidines

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