• 1. Alumina grafted SBA-15 sustainable bifunctional catalysts for direct cross-coupling of benzylic alcohols to diarylmethanes?
  Chandran Rajendran,Govindaswamy Satishkumar,Charlotte Lang,Eric M. Gaigneaux Catal. Sci. Technol., 2020,10, 2583-2592
• 2. An interplay between electronic and structural effects on the photoluminescence decay mechanisms in LaPO4·nH2O:Tb3+ and LaPO4:Tb3+ single-crystal nanorods?
  M. T. Colomer,S. Díaz-Moreno,A. Tamayo,A. L. Ortiz J. Mater. Chem. C, 2018,6, 12643-12651
• 3. Aggregated-fluorescent detection of PFAS with a simple chip
  Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
• 4. An approach to C–N activation: coupling of arenesulfonyl hydrazides and arenesulfonyl chlorides with tert-amines via a metal-, oxidant- and halogen-free anodic oxidation??
  M. Sheykhan,S. Khani,S. Shaabanzadeh,M. Joafshan Green Chem., 2017,19, 5940-5948
• 5. Acentric and chiral heterometallic inorganic–organic hybrid frameworks mediated by alkali or alkaline earth ions: synthesis and NLO properties
  Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzene and substituted derivatives
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives
• Solvents and Organic Chemicals Organic Compounds Acids/Esters
• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

Comprehensive Guide to Diphenylacetylene (CAS No. 501-65-5): Properties, Applications, and Industry Insights

Diphenylacetylene (CAS No. 501-65-5), also known as tolan or 1,2-diphenylethyne, is a highly versatile organic compound widely used in research and industrial applications. This symmetrical alkyne features two phenyl groups bonded to a triple-bonded carbon pair, making it a valuable building block in synthetic chemistry. Its unique molecular structure contributes to its stability and reactivity, enabling diverse transformations under controlled conditions.

The compound's thermal stability and photophysical properties have attracted significant attention in materials science. Researchers frequently investigate Diphenylacetylene derivatives for potential applications in organic electronics, including OLED materials and molecular wires. Recent studies explore its role in developing advanced polymers with tailored mechanical and optical characteristics, addressing growing demands in the sustainable materials sector.

In pharmaceutical research, CAS 501-65-5 serves as a crucial intermediate for synthesizing biologically active compounds. Its rigid structure facilitates the creation of molecular scaffolds for drug discovery, particularly in developing kinase inhibitors and anti-inflammatory agents. The compound's click chemistry compatibility makes it valuable for bioconjugation applications, supporting advancements in targeted drug delivery systems.

The synthesis of Diphenylacetylene typically involves Sonogashira coupling or elimination reactions from stilbene derivatives. Modern green chemistry approaches emphasize catalyst optimization and solvent reduction to improve sustainability. Analytical characterization employs NMR spectroscopy, mass spectrometry, and X-ray crystallography to verify purity and structure, meeting stringent quality control standards for research applications.

Industrial applications leverage Diphenylacetylene's properties in specialty chemicals production. Its incorporation into liquid crystal formulations enhances display technologies, while its use in coordination chemistry supports catalyst development for polymerization processes. The compound's UV absorption characteristics make it suitable for optical materials in various high-tech applications.

Emerging research explores Diphenylacetylene-based MOFs (Metal-Organic Frameworks) for gas storage and separation technologies. These porous materials demonstrate potential for carbon capture applications, aligning with global climate change mitigation efforts. Additionally, scientists investigate its supramolecular assemblies for developing molecular machines and nanoscale devices.

Safety considerations for handling 501-65-5 emphasize standard laboratory precautions. Proper personal protective equipment (PPE) including gloves and safety glasses is recommended. Storage typically occurs in airtight containers under inert atmosphere to prevent degradation, with attention to moisture control and temperature regulation for long-term stability.

The commercial availability of Diphenylacetylene meets various purity grades, from technical grade (90-95%) to HPLC grade (≥99%). Suppliers provide detailed certificates of analysis including melting point (62-64°C) and spectroscopic data. Current market trends show growing demand from Asia-Pacific research institutions and specialty chemical manufacturers expanding their high-value product portfolios.

Environmental considerations for Diphenylacetylene focus on waste minimization strategies. Researchers develop catalytic recycling methods and degradation protocols to reduce ecological impact. The compound's low water solubility and moderate volatility require specific containment measures during industrial processes, with increasing adoption of closed-system technologies.

Future perspectives highlight Diphenylacetylene's role in materials innovation. Ongoing studies investigate its electrochemical properties for energy storage applications and photocatalytic systems. The compound's versatility ensures continued relevance across multidisciplinary research areas, from nanotechnology to medicinal chemistry, driving scientific progress in the 21st century.

• 2749-93-1(Benzene,1-methyl-4-(1-propyn-1-yl)-)
• 832744-37-3(Benzene, 1-(phenylethynyl)-3-[[4-(phenylethynyl)phenyl]ethynyl]-)
• 3287-02-3(Benzene,1-methyl-4-(2-phenylethynyl)-)
• 1849-27-0(1,\u200b4-\u200bBis(phenylethynyl)\u200bbenzene)
• 118688-56-5(1,3,5-Tri(phenylethynyl)benzene)
• 153295-62-6(Benzene,1-ethynyl-4-[2-(4-ethynylphenyl)ethynyl]-)
• 673-32-5(1-Phenyl-1-propyne)
• 18826-62-5(Benzene,1-methyl-3-(1-propyn-1-yl)-)
• 19339-46-9(Tolan-d10)
• 57403-59-5(2-Propynylium, 3-phenyl-)