Cas no 497223-28-6 (Cenicriviroc Mesylate)

Cenicriviroc Mesylate is a potent, orally bioavailable dual antagonist of CCR2 and CCR5 chemokine receptors. It exhibits high selectivity and affinity for these receptors, which play critical roles in inflammatory and fibrotic pathways. The mesylate salt form enhances solubility and stability, facilitating formulation development. Preclinical and clinical studies suggest its potential in modulating immune responses, particularly in conditions like non-alcoholic steatohepatitis (NASH) and liver fibrosis. Its dual-receptor inhibition offers a unique mechanism to target inflammation and fibrogenesis simultaneously. The compound demonstrates favorable pharmacokinetic properties, including good oral absorption and sustained receptor occupancy, supporting its therapeutic potential in chronic inflammatory diseases.
Cenicriviroc Mesylate structure
Cenicriviroc Mesylate structure
Product Name:Cenicriviroc Mesylate
CAS No:497223-28-6
MF:C42H56N4O7S2
MW:793.046648979187
MDL:MFCD28502077
CID:1527759
PubChem ID:11285791
Update Time:2025-10-12

Cenicriviroc Mesylate Chemical and Physical Properties

Names and Identifiers

    • 1-Benzazocine-5-carboxamide,8-[4-(2-butoxyethoxy)phenyl]-1,2,3,4-tetrahydro-1-(2-methylpropyl)-N-[4-[(S)-[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl]phenyl]-,monomethanesulfonate
    • 1-Benzazocine-5-carboxamide,8-[4-(2-butoxyethoxy)phenyl]-1,2,3,4-tetrahydro-1-(2-methylpropyl)-N-[4-[(S)-[(1-propyl-1H-imidaz
    • Cenicriviroc Mesylate
    • (5E)-8-[4-(2-Butoxyethoxy)phenyl]-1-(2-methylpropyl)-N-[4-[(3-propylimidazol-4-yl)methylsulfinyl]phe
    • TAK-652 Mesylate
    • TBR-652 Mesylate
    • Cenicriviroc mesylate (USAN)
    • BCP29615
    • R96TV84T21
    • 497223-28-6
    • D09879
    • (5E)-8-[4-(2-butoxyethoxy)phenyl]-1-(2-methylpropyl)-N-[4-[(S)-(3-propylimidazol-4-yl)methylsulfinyl]phenyl]-3,4-dihydro-2H-1-benzazocine-5-carboxamide;methanesulfonic acid
    • (S)-8-(4-(2-Butoxyethoxy)phenyl)-1-(2-methylpropyl)-N-(4-(((1-propyl-1H-imidazol- 5- yl)methyl)sulfinyl)phenyl)-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide monomethanesulfonate
    • Cenicriviroc mesylate [USAN]
    • CS-0032631
    • AT24148
    • TAK652
    • CHEMBL2105686
    • HY-14882A
    • Cenicriviroc mesilate
    • AC-33239
    • BC179069
    • 1-BENZAZOCINE-5-CARBOXAMIDE, 8-(4-(2-BUTOXYETHOXY)PHENYL)-1,2,3,4-TETRAHYDRO-1-(2-METHYLPROPYL)-N-(4-((S)-((1-PROPYL-1H-IMIDAZOL-5-YL)METHYL)SULFINYL)PHENYL)-, METHANESULFONATE (1:1)
    • SCHEMBL3459511
    • CENICRIVIROC MESILATE [WHO-DD]
    • TBR-652 Mesylate; TAK-652 Mesylate
    • 1-Benzazocine-5-carboxamide, 8-(4-(2-butoxyethoxy)phenyl)-1,2,3,4-tetrahydro-1-(2- methylpropyl)-N-(4-((S)-((1-propyl-1H-imidazol-5-yl)methyl)sulfinyl)phenyl)-, methanesulfonate (1:1)
    • DA-72076
    • MS-31460
    • (S)-8-(4-(2-BUTOXYETHOXY)PHENYL)-1-(2-METHYLPROPYL)-N-(4-(((1-PROPYL-1H-IMIDAZOL-5-YL)METHYL)SULFINYL)PHENYL)-1,2,3,4-TETRAHYDRO-1-BENZAZOCINE-5-CARBOXAMIDE MONOMETHANESULFONATE
    • TBR 652
    • UNII-R96TV84T21
    • Q27287993
    • SCHEMBL3459507
    • EX-A3353
    • TBR-652
    • TAK-652
    • MDL： MFCD28502077
    • Inchi： 1S/C41H52N4O4S.CH4O3S/c1-5-7-22-48-23-24-49-38-15-10-32(11-16-38)33-12-19-40-35(25-33)26-34(9-8-21-44(40)28-31(3)4)41(46)43-36-13-17-39(18-14-36)50(47)29-37-27-42-30-45(37)20-6-2;1-5(2,3)4/h10-19,25-27,30-31H,5-9,20-24,28-29H2,1-4H3,(H,43,46);1H3,(H,2,3,4)/b34-26+;
    • InChI Key： IXPBPUPDRDCRSY-WNRKZQPVSA-N
    • SMILES： S(CC1=CN=CN1CCC)(C1C=CC(=CC=1)NC(C1=CC2C=C(C3C=CC(=CC=3)OCCOCCCC)C=CC=2N(CCC1)CC(C)C)=O)=O.S(C)(=O)(=O)O |t:20|

Computed Properties

  • Exact Mass: 792.35904249g/mol
  • Monoisotopic Mass: 792.35904249g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 10
  • Heavy Atom Count: 55
  • Rotatable Bond Count: 17
  • Complexity: 1150
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 168

Cenicriviroc Mesylate Security Information

  • Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month

Cenicriviroc Mesylate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
ChemScence
CS-0032631-1mg
Cenicriviroc Mesylate
 497223-28-6 98.84%
1mg
 $90.0 2022-04-27
ChemScence
CS-0032631-5mg
Cenicriviroc Mesylate
 497223-28-6 98.84%
5mg
 $160.0 2022-04-27
ChemScence
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 497223-28-6 98.84%
10mg
 $260.0 2022-04-27
ChemScence
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 497223-28-6 98.84%
25mg
 $520.0 2022-04-27
ChemScence
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 497223-28-6 98.84%
50mg
 $880.0 2022-04-27
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.
ajce55542-1mg
Cenicriviroc Mesylate
 497223-28-6 98%
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 ￥988.00 2023-09-07
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.
ajce55542-5mg
Cenicriviroc Mesylate
 497223-28-6 98%
5mg
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WU HAN AN JIE KAI Biomedical Technology Co., Ltd.
ajce55542-10mg
Cenicriviroc Mesylate
 497223-28-6 98%
10mg
 ￥4450.00 2023-09-07
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.
ajce55542-25mg
Cenicriviroc Mesylate
 497223-28-6 98%
25mg
 ￥8946.00 2023-09-07
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.
ajce55542-50mg
Cenicriviroc Mesylate
 497223-28-6 98%
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 ￥13935.00 2023-09-07

Cenicriviroc Mesylate Suppliers

Amadis Chemical Company Limited
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(CAS:497223-28-6)Cenicriviroc Mesylate
Order Number:A946301
Stock Status:in Stock
Quantity:10mg/25mg/50mg/100mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 15:54
Price ($):176.0/351.0/594.0/882.0

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Amadis Chemical Company Limited
(CAS:497223-28-6)Cenicriviroc Mesylate
A946301
Purity:99%/99%/99%/99%
Quantity:10mg/25mg/50mg/100mg
Price ($):176.0/351.0/594.0/882.0
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