Cas no 49609-84-9 (2-Chloronicotinoyl chloride)
2-Chloronicotinoyl chloride (CAS 2942-59-8) is a versatile chemical intermediate primarily used in pharmaceutical and agrochemical synthesis. This compound features a reactive acyl chloride group and a chlorinated pyridine ring, enabling efficient nucleophilic substitution and acylation reactions. Its high reactivity makes it valuable for constructing nicotinamide derivatives and other heterocyclic frameworks. The presence of the chlorine substituent enhances electrophilicity, facilitating further functionalization. 2-Chloronicotinoyl chloride is typically handled under anhydrous conditions due to its moisture sensitivity. It is employed in the production of active pharmaceutical ingredients (APIs) and crop protection agents, offering precise control over molecular architecture in complex synthetic pathways.
2-Chloronicotinoyl chloride structure
Product Name:2-Chloronicotinoyl chloride
CAS No:49609-84-9
MF:C6H3Cl2NO
MW:176.000119447708
MDL:MFCD00051677
CID:55746
PubChem ID:24869336
Update Time:2025-05-27
2-Chloronicotinoyl chloride Chemical and Physical Properties
Names and Identifiers
-
- 2-Chloronicotinoyl chloride
- 2-Chloropyridine-3-carbonyl chloride
- 2-Chloro-nicotinoyl chloride
- 2-Chloronicotinyl Chloride
- 2-chloro nicotinoyl chloride
- DTXSID80379089
- SY001379
- 2-chloronicotinic acid chloride
- AC-5010
- CS-10580
- NS00125180
- AM100875
- 2-Chloronicotinylchloride
- InChI=1/C6H3Cl2NO/c7-5-4(6(8)10)2-1-3-9-5/h1-3
- 2-Chloropyridine-3-carbonyl chloride, 98%
- MFCD00051677
- C1604
- EN300-36788
- F10901
- SCHEMBL105459
- 49609-84-9
- BB 0218403
- 3-Pyridinecarbonyl chloride, 2-chloro-
- 2-chloro-3-pyridinecarbonyl chloride
- 2-chloro-3-pyridinecarboxylic acid chloride
- AKOS005721021
- BP-10808
- R2GYX48BG7
- chloronicotinoyl chloride
- 2-chloro-3-pyridinylcarbonyl chloride
- FT-0611979
- 2-chloro nicotinic acid chloride
- 2-chloronicotinoylchloride
- STL137775
- ALBB-016422
- DB-013324
-
- MDL： MFCD00051677
- Inchi： 1S/C6H3Cl2NO/c7-5-4(6(8)10)2-1-3-9-5/h1-3H
- InChI Key： RXTRRIFWCJEMEL-UHFFFAOYSA-N
- SMILES： ClC1C(C(=O)Cl)=CC=CN=1
- BRN： 119022
Computed Properties
- Exact Mass: 174.95900
- Monoisotopic Mass: 174.959
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 10
- Rotatable Bond Count: 1
- Complexity: 140
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 2.3
- Topological Polar Surface Area: 30A^2
Experimental Properties
- Color/Form: solid
- Density: 1.2942 (rough estimate)
- Melting Point: 38.0 to 42.0 deg-C
- Boiling Point: 120°C/10mmHg(lit.)
- Flash Point: Degrees Fahrenheit:235.4°F
Degrees Celsius:113°C - Refractive Index: 1.5680 (estimate)
- PSA: 29.96000
- LogP: 2.11400
- Sensitiveness: Moisture Sensitive
- Solubility: Not determined
2-Chloronicotinoyl chloride Security Information
-
Symbol:
- Prompt：dangerous
- Signal Word：Danger
- Hazard Statement： H314
- Warning Statement： P280,P305+P351+P338,P310
- Hazardous Material transportation number：3096
- WGK Germany：3
- Hazard Category Code： 34
- Safety Instruction： S22-S26-S30-S36/37/39-S45-S8-S27
-
Hazardous Material Identification：
- HazardClass：8
- PackingGroup：III
- Storage Condition：0-10°C
- Risk Phrases：R14; R29; R34
- Packing Group：II
- Safety Term：8
- Packing Group：II
- Hazard Level：8
2-Chloronicotinoyl chloride Customs Data
- HS CODE：2933399090
- Customs Data：
China Customs Code:
2933399090Overview:
2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
2-Chloronicotinoyl chloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 045188-5g |
2-Chloronicotinoyl chloride |
49609-84-9 | 97% | 5g |
￡36.00 | 2022-03-01 | |
| Fluorochem | 045188-25g |
2-Chloronicotinoyl chloride |
49609-84-9 | 97% | 25g |
￡122.00 | 2022-03-01 | |
| Fluorochem | 045188-100g |
2-Chloronicotinoyl chloride |
49609-84-9 | 97% | 100g |
￡228.00 | 2022-03-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C119939-100g |
2-Chloronicotinoyl chloride |
49609-84-9 | 98% | 100g |
￥902.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C119939-1g |
2-Chloronicotinoyl chloride |
49609-84-9 | 98% | 1g |
￥36.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C119939-25g |
2-Chloronicotinoyl chloride |
49609-84-9 | 98% | 25g |
￥283.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C119939-5g |
2-Chloronicotinoyl chloride |
49609-84-9 | 98% | 5g |
￥96.90 | 2023-09-03 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R020315-100g |
2-Chloronicotinoyl chloride |
49609-84-9 | 98% | 100g |
￥893 | 2024-05-23 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R020315-25g |
2-Chloronicotinoyl chloride |
49609-84-9 | 98% | 25g |
￥277 | 2024-05-23 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R020315-5g |
2-Chloronicotinoyl chloride |
49609-84-9 | 98% | 5g |
￥95 | 2024-05-23 |
2-Chloronicotinoyl chloride Suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:49609-84-9)2-氯煙酰氯
Order Number:LE1748402
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:35
Price ($):discuss personally
Email:[email protected]
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:49609-84-9)2-Chloronicotinoyl chloride
Order Number:A7387
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:04
Price ($):614.0
Email:[email protected]
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:49609-84-9)2-Chloronicotinyl chloride
Order Number:sfd8073
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally
Email:[email protected]
2-Chloronicotinoyl chloride Related Literature
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I. Volovych,M. Neumann,M. Schmidt,G. Buchner,Ji-Yoon Yang,J. W?lk,T. Sottmann,R. Strey,R. Schom?cker,M. Schwarze RSC Adv. 2016 6 58279
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Y. Fang,G. K. Tranmer Org. Biomol. Chem. 2016 14 10799
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Chaoren Shen,Xiao-Feng Wu Catal. Sci. Technol. 2015 5 4433
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Benjamin Willy,Walter Frank,Thomas J. J. Müller Org. Biomol. Chem. 2010 8 90
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Francesc A. Esteve-Turrillas,Josep V. Mercader,Consuelo Agulló,Javier Marzo,Antonio Abad-Somovilla,Antonio Abad-Fuentes Analyst 2014 139 3636
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