• 1. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?
  Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
• 2. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
• 3. Evolution of important glucosinolates in three common Brassica vegetables during their processing into vegetable powder and in vitro gastric digestion
  Nan Fu,Naphaporn Chiewchan,Xiao Dong Chen Food Funct., 2020,11, 211-220
• 4. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
• 5. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imaging
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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

CAS No. 49607-01-4: (2R)-2-amino-2-cyclopropyl-acetic acid

CAS No. 49607-01-4, also known as (2R)-2-amino-2-cyclopropyl-acetic acid, is a chiral amino acid derivative with significant potential in various fields of chemical and pharmaceutical research. This compound has garnered attention due to its unique structural features and promising applications in drug discovery and development.

The structure of (2R)-2-amino-2-cyclopropyl-acetic acid consists of a central carbon atom bonded to an amino group, a cyclopropyl group, and two carboxylic acid groups. The cyclopropyl group introduces strain into the molecule, which can influence its reactivity and interactions with biological systems. The amino group provides nucleophilic character, while the carboxylic acid groups contribute acidic properties, making this compound versatile in chemical reactions.

Recent studies have highlighted the importance of (2R)-2-amino-2-cyclopropyl-acetic acid in the development of peptide-based drugs. Its chiral center allows for enantioselective synthesis, which is crucial in producing drugs with high efficacy and reduced side effects. Researchers have explored its role as a building block in peptide synthesis, where its unique stereochemistry can enhance the bioavailability and stability of resulting compounds.

In terms of synthesis, (2R)-2-amino-2-cyclopropyl-acetic acid can be prepared through various methods, including enzymatic resolution and asymmetric catalysis. These methods ensure high optical purity, which is essential for its application in pharmaceuticals. Recent advancements in asymmetric synthesis have made it possible to produce this compound on a larger scale, making it more accessible for research and industrial use.

The biological activity of (2R)-2-amino-2-cyclopropyl-acetic acid has been extensively studied. It has shown potential as an inhibitor of certain enzymes involved in metabolic pathways, making it a candidate for treating metabolic disorders. Additionally, its ability to modulate ion channels has been explored in the context of neurodegenerative diseases.

From an environmental perspective, (2R)-2-amino-2-cyclopropyl-acetic acid exhibits low toxicity profiles under standard laboratory conditions. Its degradation pathways have been investigated to ensure minimal environmental impact during its production and use.

In conclusion, CAS No. 49607-01-4, or (2R)-2-amino-2-cyclopropyl-acetic acid, represents a valuable compound with diverse applications in chemistry and pharmacology. Its unique structure and properties continue to drive innovative research, positioning it as a key player in the development of novel therapeutic agents.

• 5687-71-8(Cyclopropaneacetic acid, a-amino-)
• 1219429-81-8(Amino(cyclopropyl)acetic Acid Hydrochloride)
• 777031-77-3(Cyclopropaneaceticacid, a,2-diamino-)
• 49606-99-7(H-Cyclopropyl-Gly-OH)
• 15785-26-9(Aminocyclopropylacetic Acid)
• 36380-69-5(alpha-Amino-1,2-cyclopropanediacetic acid)
• 2228122-01-6(2-Amino-2-(1-butylcyclopropyl)acetic acid)
• 139132-43-7(2-Amino-2-(1-methylcyclopropyl)acetic acid)
• 1354350-40-5(2-amino-3-cyclopropylbutanoic acid)
• 49607-02-5(2-Amino-2-cyclopropylacetic acid hydrochloride)