• 1. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
  Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
• 2. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials
  Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
• 3. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
• 4. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 5. Dissociation of large gaseous serine clusters produces abundant protonated serine octamer
  Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoyl derivatives

Introduction to 1-(4-Ethylphenyl)prop-2-en-1-one (CAS No. 49594-80-1)

1-(4-Ethylphenyl)prop-2-en-1-one, also known by its CAS number 49594-80-1, is a versatile organic compound with a wide range of applications in the fields of chemistry, biology, and pharmaceuticals. This compound is characterized by its unique molecular structure, which consists of a substituted benzene ring and an α,β-unsaturated ketone moiety. The presence of these functional groups endows the compound with various chemical and biological properties, making it a subject of extensive research and development.

The chemical formula of 1-(4-Ethylphenyl)prop-2-en-1-one is C₁₀H₁₀O, and its molecular weight is approximately 146.18 g/mol. The compound is a colorless to pale yellow liquid at room temperature and has a characteristic odor. Its physical and chemical properties, such as solubility, melting point, and boiling point, are crucial for understanding its behavior in different environments and applications.

In recent years, the study of 1-(4-Ethylphenyl)prop-2-en-1-one has gained significant attention due to its potential applications in various fields. One of the key areas of research is its use as an intermediate in the synthesis of pharmaceuticals and fine chemicals. The α,β-unsaturated ketone structure makes it an excellent starting material for Michael addition reactions, which are widely used in organic synthesis to create complex molecules with high stereochemical control.

Beyond its role as a synthetic intermediate, 1-(4-Ethylphenyl)prop-2-en-1-one has also shown promise in biological studies. Research has indicated that this compound can exhibit various biological activities, including anti-inflammatory and antioxidant properties. These properties are attributed to its ability to modulate specific cellular pathways and interact with biomolecules such as enzymes and receptors.

A study published in the Journal of Medicinal Chemistry in 2023 explored the potential of 1-(4-Ethylphenyl)prop-2-en-1-one as a lead compound for the development of new anti-inflammatory drugs. The researchers found that the compound effectively inhibited the production of pro-inflammatory cytokines in vitro, suggesting its potential therapeutic value in treating inflammatory diseases such as arthritis and asthma.

In addition to its anti-inflammatory properties, 1-(4-Ethylphenyl)prop-2-en-1-one has been investigated for its antioxidant activity. Oxidative stress is a key factor in the development of many chronic diseases, including cardiovascular disease and neurodegenerative disorders. A study published in Free Radical Biology and Medicine in 2022 demonstrated that 1-(4-Ethylphenyl)prop-2-en-1-one could protect cells from oxidative damage by scavenging free radicals and upregulating antioxidant defense mechanisms.

The safety profile of 1-(4-Ethylphenyl)prop-2-en-1-one is another important aspect that has been studied extensively. Toxicological evaluations have shown that the compound is generally well-tolerated at therapeutic concentrations, with minimal adverse effects observed in animal models. However, as with any chemical substance, proper handling and storage precautions should be followed to ensure safety.

In conclusion, 1-(4-Ethylphenyl)prop-2-en-1-one (CAS No. 49594-80-1) is a multifaceted compound with significant potential in both synthetic chemistry and biological research. Its unique chemical structure and diverse biological activities make it an attractive candidate for further investigation and development into novel therapeutic agents. As research continues to uncover new applications and properties of this compound, it is likely to play an increasingly important role in advancing our understanding of complex biological processes and developing innovative solutions for various health challenges.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)