Cas no 494-97-3 (3-[(2S)-pyrrolidin-2-yl]pyridine)
3-[(2S)-pyrrolidin-2-yl]pyridine Chemical and Physical Properties
Names and Identifiers
-
- (S)-3-(Pyrrolidin-2-yl)pyridine
- (S)-2-(3-Pyridyl)pyrrolidine
- (s)-nicotin
- dl-Norcitine
- l-Nor-nicotine
- Nicotine, 1'-demethyl-, (S)-
- Nornicotin
- Pyridine, 3-(2-pyrrolidinyl)-, (S)-
- (S)-3-(Pyrrolidin-2-yl)pyridine hydrochloride
- (S)-Nornicotine
- (S)-(-)-Nornicotine
- 2-(3-Pyridyl)pyrrolidine
- 3-(2-Pyrrolidinyl)pyridine
- Pyridine, 3-(2S)-2-pyrrolidinyl-
- NORNICOTINE, DL-(RG)
- 1'-Demethyl nicotine
- 3-[(2S)-pyrrolidin-2-yl]pyridine
- S-(-)-Nornicotine
- (S)-1'-demethylnicotine
- Pyridine, 3-(2-pyrrolidinyl)-,(S)-
- 83H6L5QD8Z
- Demethylnicotine
- (-)-nornicotine
- 1''-demethyl nicotine
- (S)-3-Pyrrolidin-2-yl-pyridine
- 1'-demethylnicotine
- CHEBI:28313
- NICOTINE DITARTRATE DIHYDRATE IMPURITY F [EP IMPURITY]
- DTXSID7075420
- HSDB 8034
- NORNICOTINE [MI]
- EN300-96072
- BRN 0081968
- 5-23-06-00062 (Beilstein Handbook Reference)
- SCHEMBL158146
- MFCD03703484
- NICOTINE IMPURITY F [EP IMPURITY]
- NICOTINE RESINATE IMPURITY F [EP IMPURITY]
- (S)-1''-demethylnicotine
- A827730
- 3-(2-pyrrolidinyl)-(s)-pyridine
- CHEMBL6200
- UNII-83H6L5QD8Z
- DS-15937
- 494-97-3
- 3-(2S)-2-PYRROLIDINYLPYRIDINE
- US8609708, 90 Nornicotine
- MYKUKUCHPMASKF-VIFPVBQESA-N
- NICOTINE, 1'-DEMETHYL-
- NS00000596
- CS3561
- HY-W040430
- (-)-(S)-Nornicotine
- CS-W021170
- AKOS006277281
- BDBM50035415
- 3-[(2S)-2-pyrrolidinyl]pyridine
- 3-((2S)-PYRROLIDIN-2-YL)PYRIDINE
- MLS001424032
- (+-)-1'-Demethylnicotine
- (R,S)-Nornicotine
- SMR000449277
- MLS000758240
- (R)-3-(Pyrrolidin-2-yl)pyridine
- (+)-Nornicotine
- (+-)-3-(2-Pyrrolidinyl)pyridine
- Nornicotine
- (+-)-1'-demethyl-Nicotine
- MLSMR
- (+-)-Nornicotine
-
- MDL: MFCD03703484
- Inchi: 1S/C9H12N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7,9,11H,2,4,6H2/t9-/m0/s1
- InChI Key: MYKUKUCHPMASKF-VIFPVBQESA-N
- SMILES: N1CCC[C@H]1C1C=NC=CC=1
- BRN: 0081968
Computed Properties
- Exact Mass: 148.10016
- Monoisotopic Mass: 148.100048391g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 125
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.2
- Topological Polar Surface Area: 24.9
Experimental Properties
- Color/Form: Powder
- Density: d420 1.0737
- Boiling Point: bp 270°; bp11 131°; bp3 105-107°
- Refractive Index: nD20 1.5378
- PSA: 24.92
- LogP: log Kow = 0.17
- Specific Rotation: D22 -89° (c = 100)
3-[(2S)-pyrrolidin-2-yl]pyridine Security Information
- Signal Word:Warning
- Hazard Statement: H302-H319
- Warning Statement: P305+P351+P338
- Safety Instruction: H303+H313+H333
- Storage Condition:Please store the product under the recommended conditions in the Certificate of Analysis.
3-[(2S)-pyrrolidin-2-yl]pyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
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| Alichem | A029190094-250mg |
(S)-3-(Pyrrolidin-2-yl)pyridine |
494-97-3 | 95% | 250mg |
$168.00 | 2023-09-01 | |
| Alichem | A029190094-1g |
(S)-3-(Pyrrolidin-2-yl)pyridine |
494-97-3 | 95% | 1g |
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(S)-3-(Pyrrolidin-2-yl)pyridine |
494-97-3 | 95% | 1g |
$374 | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-OX047-1g |
3-[(2S)-pyrrolidin-2-yl]pyridine |
494-97-3 | 95% | 1g |
3931.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-OX047-200mg |
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494-97-3 | 95% | 200mg |
1123.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-OX047-50mg |
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494-97-3 | 95% | 50mg |
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| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-OX047-100mg |
3-[(2S)-pyrrolidin-2-yl]pyridine |
494-97-3 | 95% | 100mg |
725CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-OX047-250mg |
3-[(2S)-pyrrolidin-2-yl]pyridine |
494-97-3 | 95% | 250mg |
1495CNY | 2021-05-08 | |
| JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd. | 75R0923-1g |
(S)-3-Pyrrolidin-2-yl-pyridine |
494-97-3 | 97% | 1g |
13399.07CNY | 2021-07-19 | |
| JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd. | 75R0923-5g |
(S)-3-Pyrrolidin-2-yl-pyridine |
494-97-3 | 97% | 5g |
49864.89CNY | 2021-07-19 |
3-[(2S)-pyrrolidin-2-yl]pyridine Suppliers
3-[(2S)-pyrrolidin-2-yl]pyridine Related Literature
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Govind Reddy Mol. Syst. Des. Eng., 2021,6, 779-789
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Kui Wu,Zhihua Yang,Shilie Pan Dalton Trans., 2015,44, 19856-19864
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P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
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Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
Additional information on 3-[(2S)-pyrrolidin-2-yl]pyridine
Exploring the Chemistry and Applications of 3-[(2S)-pyrrolidin-2-yl]pyridine (CAS No. 494-97-3)
3-[(2S)-pyrrolidin-2-yl]pyridine, with the CAS number 494-97-3, is a chiral organic compound that has garnered significant attention in the fields of medicinal chemistry, neuroscience, and synthetic biology. This molecule, often referred to in scientific literature for its structural uniqueness, combines a pyridine ring with a pyrrolidine moiety in a specific stereochemical configuration, making it a valuable scaffold for research and development. Its chemical structure features a nitrogen-containing heterocycle, which contributes to its ability to interact with various biological targets, particularly in the central nervous system. Researchers and industry professionals frequently search for terms like "3-[(2S)-pyrrolidin-2-yl]pyridine synthesis" and "CAS 494-97-3 applications" to explore its potential in drug discovery and beyond, aligning with current trends in personalized medicine and AI-driven molecular design.
The physical and chemical properties of 3-[(2S)-pyrrolidin-2-yl]pyridine include a molecular weight of approximately 162.23 g/mol, a boiling point estimated around 280-290°C, and solubility in common organic solvents such as ethanol and dimethyl sulfoxide (DMSO). Its chirality, denoted by the (2S) configuration, is crucial for its biological activity, as enantiopure forms often exhibit distinct interactions with enzymes and receptors. This aspect ties into hot topics like "chiral compounds in pharmaceuticals" and "stereoselective synthesis", which are highly searched in databases and AI platforms due to their relevance in developing more effective and safer therapeutics. The compound's stability under standard conditions makes it suitable for laboratory use, but handling should always follow good practices to ensure safety and purity.
In terms of synthesis and production, 3-[(2S)-pyrrolidin-2-yl]pyridine is typically prepared through multi-step organic reactions, often starting from readily available precursors like pyridine derivatives and L-proline, which provides the chiral pyrrolidine unit. Methods such as asymmetric catalysis and enzymatic resolution are employed to achieve high enantiomeric excess, reflecting advancements in green chemistry and sustainable synthesis—a trending topic among researchers concerned with environmental impact. Queries like "how to synthesize 3-[(2S)-pyrrolidin-2-yl]pyridine" and "CAS 494-97-3 supplier" are common in search engines, highlighting the demand for efficient and scalable production techniques. This aligns with broader interests in reducing waste and improving atom economy in chemical manufacturing.
The applications of 3-[(2S)-pyrrolidin-2-yl]pyridine span several cutting-edge areas, particularly in medicinal chemistry where it serves as a key intermediate or pharmacophore in the development of novel therapeutics. It has been investigated for its potential role in modulating neurotransmitter systems, such as those involving nicotinic acetylcholine receptors, which are linked to cognitive disorders and neurological diseases. This connects to high-search-volume topics like "neuroprotective agents" and "drug discovery for Alzheimer's disease", as users often seek information on compounds that could address global health challenges. Additionally, its use in chemical biology for probe design and biomarker studies makes it relevant to trends in precision medicine and AI-assisted drug screening, where researchers leverage computational tools to predict compound behavior.
Beyond healthcare, 3-[(2S)-pyrrolidin-2-yl]pyridine finds utility in material science, such as in the synthesis of ligands for catalysis or as a building block for functionalized polymers. Its ability to coordinate with metals opens doors to applications in sensors and electronic devices, resonating with searches for "advanced materials chemistry" and "sustainable technology solutions". The compound's versatility also extends to agricultural chemistry, where it may be used in developing eco-friendly pesticides or growth regulators, though this is less explored. This multidisciplinary relevance makes it a subject of interest in academic and industrial forums, often discussed in context of innovation and cross-disciplinary research.
Market dynamics and research trends for 3-[(2S)-pyrrolidin-2-yl]pyridine indicate a growing interest, driven by increased funding for neuroscience and drug development projects. Global demand is rising, with key suppliers offering it for research purposes, and patent filings related to its derivatives have seen an uptick in recent years. Searches for "market analysis of chiral compounds" and "future of synthetic biology" reflect user curiosity about economic and scientific impacts. Furthermore, with the integration of AI and machine learning in chemistry, predictive models are being used to optimize its synthesis and applications, making it a hotspot for innovation. This compound exemplifies how traditional chemical research is evolving with technology, catering to audiences interested in both fundamental science and practical applications.
In conclusion, 3-[(2S)-pyrrolidin-2-yl]pyridine (CAS No. 494-97-3) is a multifaceted compound with significant promise in various scientific domains. Its unique chemical structure and biological activity make it a valuable tool for researchers tackling challenges in medicine, materials, and beyond. By staying informed on topics like "chiral synthesis techniques" and "emerging compounds in healthcare", professionals can leverage its potential while adhering to ethical and safe practices. As the field advances, this molecule will likely continue to inspire innovation, supported by ongoing studies and collaborative efforts across disciplines.
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