Cas no 491868-12-3 (4-Hydroxybenzyl Methanethiosulfonate)
4-Hydroxybenzyl Methanethiosulfonate is a reactive thiol-modifying reagent commonly used in protein biochemistry and bioconjugation. Its key advantage lies in its ability to selectively modify cysteine residues via disulfide bond formation, enabling site-specific labeling or crosslinking of proteins. The hydroxyphenyl group enhances solubility in aqueous buffers, facilitating reactions under physiological conditions. This compound is particularly useful for introducing stable thioether linkages or reversible modifications, making it valuable for structural studies, enzyme inhibition, and probe development. Its controlled reactivity minimizes nonspecific interactions, ensuring high specificity in protein engineering applications. The product is typically handled under inert conditions to preserve reactivity.
491868-12-3 structure
Product Name:4-Hydroxybenzyl Methanethiosulfonate
CAS No:491868-12-3
MF:C8H10O3S2
MW:218.293200016022
CID:825962
PubChem ID:3367705
Update Time:2025-06-06
4-Hydroxybenzyl Methanethiosulfonate Chemical and Physical Properties
Names and Identifiers
-
- 4-Hydroxybenzyl Methanethiosulfonate
- 4-HB-MTS
- 4-(methylsulfonylsulfanylmethyl)phenol
- 4-[(METHANESULFONYLSULFANYL)METHYL]PHENOL
- S-(4-Hydroxybenzyl) methanesulfonothioate
- DTXSID60391865
- AKOS030239735
- 491868-12-3
-
- Inchi： 1S/C8H10O3S2/c1-13(10,11)12-6-7-2-4-8(9)5-3-7/h2-5,9H,6H2,1H3
- InChI Key： YPHDQZFGAJAIEG-UHFFFAOYSA-N
- SMILES： S(C)(=O)(=O)SCC1C=CC(=CC=1)O
Computed Properties
- Exact Mass: 218.00700
- Monoisotopic Mass: 218.00713652g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 13
- Rotatable Bond Count: 3
- Complexity: 235
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.2
- Topological Polar Surface Area: 88?2
Experimental Properties
- Melting Point: 60-62°C
- Stability/Shelf Life: Solid is Stable when Frozen; Decomposes Rapidly in Solution.
- PSA: 88.05000
- LogP: 2.66580
4-Hydroxybenzyl Methanethiosulfonate Security Information
- Signal Word：warning
- Hazard Statement： H303+H313+H333
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
4-Hydroxybenzyl Methanethiosulfonate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | H829750-2mg |
4-Hydroxybenzyl Methanethiosulfonate |
491868-12-3 | 2mg |
$121.00 | 2023-05-18 | ||
| TRC | H829750-5mg |
4-Hydroxybenzyl Methanethiosulfonate |
491868-12-3 | 5mg |
$173.00 | 2023-05-18 | ||
| TRC | H829750-10mg |
4-Hydroxybenzyl Methanethiosulfonate |
491868-12-3 | 10mg |
$ 328.00 | 2023-09-07 | ||
| TRC | H829750-25mg |
4-Hydroxybenzyl Methanethiosulfonate |
491868-12-3 | 25mg |
$ 719.00 | 2023-09-07 | ||
| TRC | H829750-50mg |
4-Hydroxybenzyl Methanethiosulfonate |
491868-12-3 | 50mg |
$1355.00 | 2023-05-18 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-206894-5 mg |
4-Hydroxybenzyl Methanethiosulfonate, |
491868-12-3 | 5mg |
￥2,106.00 | 2023-07-11 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-206894-5mg |
4-Hydroxybenzyl Methanethiosulfonate, |
491868-12-3 | 5mg |
￥2106.00 | 2023-09-05 | ||
| TRC | H829750-2.5mg |
4-Hydroxybenzyl Methanethiosulfonate |
491868-12-3 | 2.5mg |
$ 121.00 | 2023-09-07 |
4-Hydroxybenzyl Methanethiosulfonate Related Literature
-
Huifang Yang,Haoran Guo,Peidong Fan,Xinpan Li,Wenlu Ren,Rui Song Nanoscale, 2020,12, 7024-7034
-
Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
-
Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
-
Karl Crowley,Eimer O'Malley,Aoife Morrin,Malcolm R. Smyth,Anthony J. Killard Analyst, 2008,133, 391-399
491868-12-3 (4-Hydroxybenzyl Methanethiosulfonate) Related Products
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