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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrroles Pyrrole carboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrroles Pyrrole carboxylic acids and derivatives Pyrrole carboxylic acids

1H-Pyrrole-3-carboxylic acid, 5-formyl-1-methyl- (CAS No. 482583-71-1): A Comprehensive Overview

1H-Pyrrole-3-carboxylic acid, 5-formyl-1-methyl- (CAS No. 482583-71-1) is a versatile compound that has garnered significant attention in the fields of organic chemistry, medicinal chemistry, and pharmaceutical research. This compound, also known as 5-formyl-1-methylpyrrole-3-carboxylic acid, is characterized by its unique structural features and potential applications in the development of novel therapeutic agents.

The molecular formula of 1H-Pyrrole-3-carboxylic acid, 5-formyl-1-methyl- is C₉H₉NO₃, and its molecular weight is approximately 183.17 g/mol. The compound is a white to off-white solid at room temperature and is soluble in common organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO). Its chemical structure consists of a pyrrole ring with a carboxylic acid group at the 3-position, a formyl group at the 5-position, and a methyl group at the 1-position.

Recent studies have highlighted the potential of 5-formyl-1-methylpyrrole-3-carboxylic acid in various biological and medicinal applications. One of the key areas of interest is its role as an intermediate in the synthesis of bioactive molecules. For instance, researchers have explored its use in the development of antimicrobial agents and anti-inflammatory drugs. The presence of the formyl group and the carboxylic acid group provides multiple functional handles for further chemical modifications, making it an attractive starting material for synthetic chemists.

In the realm of medicinal chemistry, 1H-Pyrrole-3-carboxylic acid, 5-formyl-1-methyl- has been investigated for its potential as a scaffold for drug discovery. Studies have shown that derivatives of this compound exhibit promising pharmacological activities, including antioxidant, anti-cancer, and neuroprotective properties. For example, a recent study published in the *Journal of Medicinal Chemistry* reported that certain derivatives of 5-formyl-1-methylpyrrole-3-carboxylic acid demonstrated significant cytotoxic activity against various cancer cell lines, suggesting its potential as a lead compound for cancer therapy.

The structural flexibility and functional diversity of 1H-Pyrrole-3-carboxylic acid, 5-formyl-1-methyl- also make it an ideal candidate for combinatorial chemistry approaches. Combinatorial libraries derived from this compound have been synthesized and screened for a wide range of biological activities. These libraries have yielded several hits with potent bioactivity, further underscoring the importance of this compound in drug discovery efforts.

Beyond its medicinal applications, 5-formyl-1-methylpyrrole-3-carboxylic acid has also found use in materials science. Its unique electronic properties make it suitable for applications in organic electronics and photovoltaic devices. Researchers have explored its use as a building block for organic semiconductors and have reported promising results in terms of charge transport properties and device performance.

In conclusion, 1H-Pyrrole-3-carboxylic acid, 5-formyl-1-methyl- (CAS No. 482583-71-1) is a multifaceted compound with a wide range of potential applications in chemistry, biology, and materials science. Its unique structural features and functional groups provide numerous opportunities for further research and development. As ongoing studies continue to uncover new properties and applications, this compound is poised to play a significant role in advancing various scientific fields.

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