• 1. Generic tags for Mn(ii) and Gd(iii) spin labels for distance measurements in proteins
  Yin Yang,Yan-Jun Gong,Aleksei Litvinov,Hong-Kai Liu,Feng Yang,Xun-Cheng Su,Daniella Goldfarb Phys. Chem. Chem. Phys. 2017 19 26944

• Solvents and Organic Chemicals Organic Compounds Organic 1,3-dipolar compounds Allyl-type 1,3-dipolar organic compounds C-nitro compounds
• Solvents and Organic Chemicals Organic Compounds Organic 1,3-dipolar compounds Allyl-type 1,3-dipolar organic compounds Organic nitro compounds C-nitro compounds

2,6-Dimethyl-4-nitropyridin-1-ium-1-olate: A Comprehensive Overview

The compound 2,6-Dimethyl-4-nitropyridin-1-ium-1-olate (CAS No. 4808-64-4) is a significant entity in the field of organic chemistry, particularly within the realm of heterocyclic compounds. This compound has garnered attention due to its unique structural properties and potential applications in various scientific domains. In this article, we delve into the chemical structure, synthesis methods, applications, and recent research advancements associated with this compound.

Chemical Structure and Properties: The molecular structure of 2,6-Dimethyl-4-nitropyridin-1-ium-1-olate is characterized by a pyridine ring system with substituents at positions 2, 4, and 6. The presence of methyl groups at positions 2 and 6, along with a nitro group at position 4, imparts distinct electronic and steric properties to the molecule. The nitro group acts as an electron-withdrawing substituent, influencing the overall reactivity and stability of the compound. Recent studies have highlighted the importance of such substituent effects in determining the compound's behavior in different chemical environments.

Synthesis and Characterization: The synthesis of 2,6-Dimethyl-4-nitropyridin-1-ium-1-olate involves a multi-step process that typically begins with the preparation of the corresponding pyridine derivative. Advanced synthetic techniques, including nucleophilic aromatic substitution and oxidation reactions, are employed to achieve the desired product. Modern characterization methods such as NMR spectroscopy, IR spectroscopy, and X-ray crystallography have been instrumental in confirming the molecular structure and purity of this compound.

Applications in Chemistry: The compound finds applications in various areas of chemistry, including pharmaceuticals, agricultural chemistry, and materials science. In pharmaceuticals, its unique electronic properties make it a promising candidate for drug design and development. Recent research has explored its potential as a precursor for bioactive molecules with anti-inflammatory and anticancer properties.

Recent Research Advancements: Over the past few years, there has been a surge in research focusing on 2,6-Dimethyl-4-nitropyridin-1-ium-1-oate due to its versatility as a building block in organic synthesis. Studies have demonstrated its role in constructing complex heterocyclic frameworks, which are essential for developing advanced materials with tailored properties.

Environmental Considerations: As with any chemical compound, understanding its environmental impact is crucial. Research into the degradation pathways and toxicity profiles of 2,6-Dimethyl...

• 5470-66-6(2-methyl-4-nitropyridine-n-oxide)
• 13508-96-8(2-methyl-4-nitro-pyridine)
• 4831-62-3( )
• 21816-42-2(2,5-dimethyl-4-nitropyridin-1-ium-1-olate)
• 14163-00-9(2,2'-Bipyridine, 4-nitro-, 1-oxide)
• 4913-57-9(2,6-Dimethyl-4-nitropyridine)
• 79078-31-2(Pyridine,2-bromomethyl-4-nitro-, 1-oxide (9CI))
• 36625-50-0(Pyridine, 2-methyl-5-nitro-, 1-oxide)
• 84175-05-3(4'-Nitro-2,2'-bipyridine-N-oxide)
• 130645-12-4(2,2'-Bipyridine, 6,6'-dimethyl-4,4'-dinitro-, 1,1'-dioxide)