Cas no 4783-82-8 (2-(4-Bromophenoxy)pyridine)

2-(4-Bromophenoxy)pyridine is a brominated aromatic compound featuring a pyridine core linked to a 4-bromophenoxy group. This structure imparts unique reactivity, making it a valuable intermediate in organic synthesis, particularly in pharmaceutical and agrochemical applications. The bromine substituent enhances its utility in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling the formation of complex biaryl or heteroaryl systems. Its stability and well-defined reactivity profile facilitate precise functionalization, supporting the development of advanced molecular architectures. The compound is typically handled under standard laboratory conditions, ensuring compatibility with a range of synthetic methodologies. Its high purity and consistent performance make it a reliable choice for research and industrial applications.
2-(4-Bromophenoxy)pyridine structure
2-(4-Bromophenoxy)pyridine structure
Product Name:2-(4-Bromophenoxy)pyridine
CAS No:4783-82-8
MF:C11H8BrNO
MW:250.09132194519
CID:327969
PubChem ID:23201935
Update Time:2025-05-20

2-(4-Bromophenoxy)pyridine Chemical and Physical Properties

Names and Identifiers

    • 2-(4-Bromophenoxy)pyridine
    • Pyridine,2-(4-bromophenoxy)-
    • 2-(2-CHLOROPHENYL)-6,8-DIMETHYLQUINOLINE-4-CARBOXYLIC ACID
    • 2-(4-bromophenoxy)-pyridine
    • 2-(p-Bromphenyloxy)-pyridin
    • 2-<4-Brom-phenoxy>-pyridin
    • 4-bromo-1-(2-pyridyloxy)benzene
    • Pyridine,2-(4-bromophenoxy)
    • 2-(4-Bromo-phenoxy)-pyridine
    • DTXSID60631258
    • AKOS000194677
    • MS-22367
    • SCHEMBL568653
    • FOKJQGKEVMZAJE-UHFFFAOYSA-N
    • CS-0260474
    • S-METHYL-L-CYSTEINEMETHYLESTERHYDROCHLORIDE
    • FT-0648028
    • 4783-82-8
    • Z54630954
    • 2-(4-bromo-phenoxy)pyridine
    • MFCD08435900
    • EN300-75291
    • Inchi: 1S/C11H8BrNO/c12-9-4-6-10(7-5-9)14-11-3-1-2-8-13-11/h1-8H
    • InChI Key: FOKJQGKEVMZAJE-UHFFFAOYSA-N
    • SMILES: BrC1C=CC(=CC=1)OC1C=CC=CN=1

Computed Properties

  • Exact Mass: 248.97900
  • Monoisotopic Mass: 248.97893g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 2
  • Complexity: 169
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.1
  • Topological Polar Surface Area: 22.1?2

Experimental Properties

  • Density: 1.476
  • Boiling Point: 116 °C
  • Flash Point: 148.8°C
  • PSA: 22.12000
  • LogP: 3.63640

2-(4-Bromophenoxy)pyridine Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-(4-Bromophenoxy)pyridine Pricemore >>

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Additional information on 2-(4-Bromophenoxy)pyridine

2-(4-Bromophenoxy)pyridine: A Comprehensive Overview

2-(4-Bromophenoxy)pyridine (CAS No. 4783-82-8) is a versatile organic compound that has garnered significant attention in the fields of chemistry, pharmacology, and materials science. This compound, characterized by its unique structure combining a pyridine ring with a bromophenoxy group, exhibits a wide range of applications and properties that make it a valuable molecule for both academic research and industrial applications.

The chemical structure of 2-(4-Bromophenoxy)pyridine is defined by a pyridine ring substituted at the 2-position with a phenoxy group, which itself is brominated at the para position. This substitution pattern imparts the molecule with distinct electronic and steric properties. Recent studies have highlighted its potential as a building block in the synthesis of advanced materials, such as coordination polymers and metal-organic frameworks (MOFs). For instance, researchers have demonstrated its ability to act as a ligand in the formation of MOFs with high surface area and porosity, which are promising for gas storage and catalytic applications.

In terms of synthesis, 2-(4-Bromophenoxy)pyridine can be prepared via various routes, including nucleophilic aromatic substitution and coupling reactions. A notable advancement in its synthesis involves the use of palladium-catalyzed cross-coupling reactions, which have enabled more efficient and selective methods. These methods not only enhance the yield but also reduce the environmental footprint of the synthesis process, aligning with current trends toward sustainable chemistry.

The application of 2-(4-Bromophenoxy)pyridine spans multiple domains. In pharmacology, it has been explored as a lead compound for drug development due to its ability to modulate key biological targets. Recent studies have shown that it exhibits potential anti-inflammatory and antioxidant activities, making it a candidate for therapeutic agents targeting chronic diseases such as neurodegenerative disorders and cardiovascular conditions.

Moreover, 2-(4-Bromophenoxy)pyridine has found utility in the field of agrochemistry. Its derivatives have been investigated for their pesticidal properties, particularly as fungicides and insecticides. The compound's ability to inhibit key enzymes involved in fungal growth has been validated in recent experiments, suggesting its potential as an eco-friendly alternative to conventional pesticides.

From an environmental perspective, understanding the degradation pathways of 2-(4-Bromophenoxy)pyridine is crucial for assessing its ecological impact. Recent research has focused on photodegradation mechanisms under UV light, revealing that the compound undergoes rapid transformation into less toxic byproducts. This insight is valuable for designing sustainable chemical processes that minimize environmental contamination.

In conclusion, 2-(4-Bromophenoxy)pyridine (CAS No. 4783-82-8) stands out as a multifaceted compound with significant potential across diverse scientific disciplines. Its unique chemical properties, coupled with advancements in synthesis and application techniques, position it as a key molecule for future innovations in materials science, pharmacology, and agrochemistry.

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