• 1. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 2. Evidence of field induced slow magnetic relaxation in cis-[Co(hfac)2(H2O)2] exhibiting tri-axial anisotropy with a negative axial component?
  Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
• 3. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
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• 4. Excellent peroxidase mimicking property of CuO/Pt nanocomposites and their application as an ascorbic acid sensor?
  Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
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  Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341

• Solvents and Organic Chemicals Organic Compounds Alcohol/Ether

Comprehensive Analysis of (2-Fluoro-6-methylphenyl)methanol (CAS No. 478163-35-8): Properties, Applications, and Industry Trends

(2-Fluoro-6-methylphenyl)methanol (CAS No. 478163-35-8) is a fluorinated aromatic alcohol with significant relevance in pharmaceutical and fine chemical synthesis. This compound, characterized by its fluoro and methyl substituents on the phenyl ring, exhibits unique chemical properties that make it valuable for intermediate applications. The growing demand for fluorinated building blocks in drug discovery has positioned this molecule as a key player in modern organic chemistry.

Recent advancements in green chemistry have spurred interest in optimizing the synthesis of (2-Fluoro-6-methylphenyl)methanol. Researchers are exploring catalytic reduction methods using sustainable catalysts to improve yield and reduce environmental impact. The compound's lipophilicity and electronic effects, imparted by the fluorine atom, make it particularly useful for modifying drug candidates' bioavailability—a hot topic in medicinal chemistry forums and AI-driven molecular design platforms.

From an industrial perspective, 478163-35-8 has gained attention in the development of advanced materials and specialty chemicals. Its structural features enable applications in liquid crystal formulations and polymer modifiers, aligning with the surge in demand for high-performance materials. Analytical techniques like HPLC and NMR are crucial for quality control, as purity requirements tighten in GMP-compliant production environments.

The safety profile of (2-Fluoro-6-methylphenyl)methanol has been extensively studied, with particular focus on its handling protocols and storage conditions. Material Safety Data Sheets (MSDS) provide detailed guidance that addresses common queries from laboratory personnel about personal protective equipment (PPE) requirements and waste disposal procedures—topics frequently searched in chemical safety databases.

Market analysts note increasing patent activity surrounding derivatives of fluorinated benzyl alcohols, with 478163-35-8 appearing in several intellectual property filings. This trend reflects the compound's versatility in creating chiral auxiliaries and asymmetric synthesis reagents—areas experiencing rapid growth due to the pharmaceutical industry's focus on enantioselective catalysis.

In analytical applications, (2-Fluoro-6-methylphenyl)methanol serves as a valuable reference standard for method development in chromatographic separation techniques. Laboratories performing impurity profiling for regulatory submissions frequently inquire about its spectral data and retention characteristics—information commonly requested through online chemical databases and AI-powered research tools.

The compound's stability under various pH conditions and temperature ranges has become a subject of recent studies, particularly for researchers developing accelerated stability testing protocols. These investigations address frequently asked questions about degradation pathways and shelf-life prediction models in pharmaceutical development circles.

Emerging applications in agrochemical research have expanded the utility of 478163-35-8, with studies demonstrating its potential as a precursor for crop protection agents. This aligns with global trends toward developing next-generation pesticides with improved environmental profiles—a topic generating substantial discussion in green agriculture initiatives.

From a regulatory standpoint, (2-Fluoro-6-methylphenyl)methanol complies with major chemical inventories including REACH and TSCA, making it accessible for international trade. Compliance documentation and export control classifications rank among the most searched aspects for procurement specialists navigating global supply chains.

Future research directions may explore the compound's potential in metal-organic frameworks (MOFs) and catalysis applications, capitalizing on the synergistic effects of its fluorine substitution and hydroxyl functionality. Such developments would address the scientific community's growing interest in multifunctional materials and smart catalysts—key phrases trending in materials science literature and AI-assisted research platforms.

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