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5-Morpholino-2-(2-oxopropyl)-3(2H)-pyridazinone (CAS No. 477845-70-8): A Comprehensive Overview

5-Morpholino-2-(2-oxopropyl)-3(2H)-pyridazinone (CAS No. 477845-70-8) is a specialized heterocyclic compound that has garnered significant attention in pharmaceutical and agrochemical research. This compound, featuring a pyridazinone core substituted with a morpholino group and a 2-oxopropyl moiety, exhibits unique chemical properties that make it valuable for various applications. Its molecular formula is C₁₁H₁₅N₃O₃, and it is often explored for its potential as a bioactive intermediate in drug discovery.

The pyridazinone scaffold is a well-known pharmacophore, and the introduction of the morpholino group enhances its solubility and bioavailability. Researchers are particularly interested in 5-morpholino-2-(2-oxopropyl)-3(2H)-pyridazinone due to its potential role in modulating enzyme activity and receptor binding. Recent studies have highlighted its relevance in the development of kinase inhibitors, which are crucial for targeting diseases like cancer and inflammatory disorders. This aligns with the growing demand for small molecule therapeutics in precision medicine.

In the agrochemical sector, 5-morpholino-2-(2-oxopropyl)-3(2H)-pyridazinone is being investigated for its herbicidal and fungicidal properties. The compound's ability to interfere with plant metabolic pathways makes it a candidate for sustainable crop protection solutions. With the global push toward reducing synthetic pesticide use, this compound could play a role in next-generation green chemistry applications.

The synthesis of 5-morpholino-2-(2-oxopropyl)-3(2H)-pyridazinone typically involves multi-step organic reactions, including condensation and cyclization processes. Advanced techniques like microwave-assisted synthesis and catalysis have been employed to improve yield and purity. Analytical methods such as HPLC and NMR spectroscopy are essential for characterizing this compound, ensuring its suitability for high-value applications.

From a market perspective, the demand for 5-morpholino-2-(2-oxopropyl)-3(2H)-pyridazinone is expected to rise, driven by its versatility in drug discovery and agrochemical innovation. Companies specializing in custom synthesis and contract research are actively offering this compound to support R&D efforts worldwide. Its compatibility with combinatorial chemistry platforms further enhances its appeal for high-throughput screening.

For researchers and industry professionals, understanding the stability and storage conditions of 5-morpholino-2-(2-oxopropyl)-3(2H)-pyridazinone is critical. The compound should be stored in a cool, dry environment, preferably under inert conditions, to maintain its integrity over time. Proper handling and disposal practices are also emphasized to align with environmental regulations.

In summary, 5-morpholino-2-(2-oxopropyl)-3(2H)-pyridazinone (CAS No. 477845-70-8) represents a promising compound with diverse applications in pharmaceuticals and agrochemicals. Its unique structural features and bioactive potential make it a subject of ongoing research, particularly in the context of targeted therapy and sustainable agriculture. As scientific advancements continue, this compound is poised to contribute significantly to innovation in these fields.

• 154321-33-2(4-Pyridazinecarboxaldehyde,2,3-dihydro-2-methyl-5-(4-morpholinyl)-3-oxo-)
• 866143-77-3(4-chloro-5-(morpholin-4-yl)-2-(2-oxopropyl)-2,3-dihydropyridazin-3-one)
• 63562-94-7(3(2H)-PYRIDAZINONE, 2-ETHYL-4-HYDROXY-5-(4-MORPHOLINYL)-)
• 63562-95-8(3(2H)-Pyridazinone, 4-hydroxy-5-(4-morpholinyl)-2-propyl-)
• 1803606-74-7(5-[(2-methoxyethyl)(methyl)amino]-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one; carbonic acid)
• 69123-72-4(3(2H)-Pyridazinone, 2-methyl-5-(4-morpholinyl)-)
• 1000018-24-5(Ethyl 2-(6-oxo-4-(piperazin-1-yl)pyridazin-1(6H)-yl)acetate)
• 1803581-21-6(5-[(2-methoxyethyl)(methyl)amino]-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one)
• 63562-93-6(3(2H)-Pyridazinone, 4-hydroxy-2-methyl-5-(4-morpholinyl)-)
• 21131-06-6(5-morpholino-3(2H)-pyridazinone)