• 1. Excimer formation effects and trap-assisted charge recombination loss channels in organic solar cells of perylene diimide dimer acceptors?
  Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
• 2. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
  Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
• 3. Dissolution of cork biopolymers in biocompatible ionic liquids
  Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
• 4. Dissociative electron attachment to HGaF4 Lewis–Br?nsted superacid
  Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
• 5. Examination of deposit in commercial diluted phosphoric acid
  Analyst, 1880,5, 146-147

2-[(Tributylstannyl)methoxy]ethanol (CAS No. 475680-87-6): An Overview of Its Properties and Applications in Chemical and Pharmaceutical Research

2-[(Tributylstannyl)methoxy]ethanol (CAS No. 475680-87-6), also known as E7922, is a versatile organic compound that has gained significant attention in the fields of chemical and pharmaceutical research. This compound is characterized by its unique structure, which includes a tributylstannyl group attached to a methoxyethanol backbone. The combination of these functional groups endows 2-[(tributylstannyl)methoxy]ethanol with a range of valuable properties, making it an essential reagent in various synthetic processes and biological studies.

The chemical structure of 2-[(tributylstannyl)methoxy]ethanol is particularly noteworthy due to its ability to participate in a variety of chemical reactions. The tributylstannyl group is a well-known organostannane that can undergo Stille coupling reactions, which are widely used in the synthesis of complex organic molecules. This reactivity makes E7922 an important intermediate in the preparation of pharmaceuticals, agrochemicals, and other fine chemicals.

In addition to its synthetic utility, 2-[(tributylstannyl)methoxy]ethanol has been studied for its potential biological activities. Recent research has shown that organostannanes, including compounds like E7922, can exhibit antimicrobial, antifungal, and antiviral properties. These findings have sparked interest in exploring the use of such compounds in the development of new therapeutic agents.

The physical properties of 2-[(tributylstannyl)methoxy]ethanol are also important for its applications. It is a colorless liquid with a molecular weight of 314.53 g/mol. The compound is soluble in common organic solvents such as dichloromethane, ethanol, and acetone, which facilitates its use in various laboratory settings. Its stability under different conditions has been well-documented, making it a reliable reagent for both academic and industrial research.

In the context of pharmaceutical research, 2-[(tributylstannyl)methoxy]ethanol has been utilized as a building block in the synthesis of drug candidates. For example, it has been employed in the development of prodrugs that can be activated under specific physiological conditions. This approach allows for targeted drug delivery and reduced side effects, which are critical factors in the design of effective therapeutic agents.

The safety profile of E7922 is another important consideration for its use in research and development. While organostannanes can be toxic at high concentrations, careful handling and proper safety protocols can mitigate these risks. Researchers should adhere to established guidelines for the safe use and disposal of organometallic compounds to ensure laboratory safety.

In conclusion, 2-[(tributylstannyl)methoxy]ethanol (CAS No. 475680-87-6), or E7922, is a valuable compound with diverse applications in chemical and pharmaceutical research. Its unique chemical structure and reactivity make it an essential reagent for synthetic processes, while its potential biological activities open up new avenues for therapeutic development. As research continues to advance, the importance of compounds like E7922 is likely to grow, contributing to the advancement of science and medicine.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)