Cas no 4755-77-5 (ethyl 2-chloro-2-oxo-acetate)
Ethyl 2-chloro-2-oxo-acetate is a versatile ester compound widely used in organic synthesis as an acylating and chloroacetylating agent. Its reactive α-chloro carbonyl group enables efficient introduction of the chloroacetyl moiety into target molecules, making it valuable in pharmaceutical and agrochemical intermediates. The compound exhibits high reactivity under mild conditions, facilitating selective transformations such as nucleophilic substitutions and condensations. Its liquid form at room temperature ensures ease of handling in laboratory and industrial settings. Ethyl 2-chloro-2-oxo-acetate is particularly useful in peptide synthesis and heterocyclic chemistry, where precise functionalization is required. Proper storage under anhydrous conditions is recommended to maintain stability.
ethyl 2-chloro-2-oxo-acetate structure
Product Name:ethyl 2-chloro-2-oxo-acetate
CAS No:4755-77-5
MF:C4H5ClO3
MW:136.533700704575
MDL:MFCD00000706
CID:45290
PubChem ID:20884
Update Time:2025-11-07
ethyl 2-chloro-2-oxo-acetate Chemical and Physical Properties
Names and Identifiers
-
- Ethyl oxalyl monochloride
- Ethyl chloroglyoxylate~Oxalic acid monoethyl ester chloride
- ethyl chlorooxoacetate
- ethyl (chloroformyl)formate
- mono-Ethyl oxalyl chloride
- ETHOXALYL CHLORIDE
- ETCOX
- ETHYL OXALYL CHLORIDE
- ETHYL CHLOROGLYOXALATE
- ETHYL CHLOROGLYOXYLATE
- Ethoxyoxalyl Chloride
- ethyl 2-chloro-2-oxoacetate
- Chloroglyoxylic Acid Ethyl Ester
- Oxalic Acid Monoethyl Ester Chloride
- Chlorooxalic acid ethyl ester
- Ethyl chloroformylformate
- ethyl 2-chloro-2-oxo-acetate
- Monoethyl oxalyl chloride
- AKOS000120204
- A827270
- ethyl chloro-oxo-acetate
- NSC 80644
- DTXSID3063598
- Glyoxylic acid, chloro-, ethyl ester; 1-(Chlorocarbonyl)formic acid ethyl ester; Chloroglyoxylic acid ethyl ester
- ethylchlorooxoacetate
- Ethoxy oxalylchloride
- chloro-oxalic acid ethyl ester
- NSC-80644
- 4755-77-5
- ethyl choroglyoxylate
- ethyl chloroglyoxylic acid
- ethyl 2-chloranyl-2-oxidanylidene-ethanoate
- Acetic acid, chlorooxo-, ethyl ester
- chloroglyoxylic ethyl ester
- BP-13267
- SCHEMBL23824
- ethyl chloro-oxoacetate
- Ethyloxalylmonochloride
- F2190-0031
- EINECS 225-285-0
- NSC80644
- chloro-oxo-acetic acid ethyl ester
- ethyl 2-chlorooxoacetate
- Acetic acid, 2-chloro-2-oxo-, ethyl ester
- EN300-20677
- FT-0626221
- Oxalyl chloride, ethyl ester
- Monoethyl oxaloyl chloride
- J-521273
- ethyl chlorooxalate
- ethyl chloro-(oxo)acetate
- 3-(2,2-DIBROMOVINYL)-2,2-DIMETHYL-(1-CYCLOPROPANE)CARBOXYLICACID(CISISOMER)POR
- AS-19169
- ethylchloro(oxo)acetate
- Ethyl (Chlorocarbonyl)formate
- Ethyl chlorooxoacetate, 98%
- ethyl chloroxalate
- MFCD00000706
- ethoxalylchloride
- BCP20422
- 2-chloro-2-oxoacetic acid ethyl ester
- Glyoxylic acid, chloro-, ethyl ester
- NS00031703
- chlorooxoacetic acid ethyl ester
- CS-0017819
- OWZFULPEVHKEKS-UHFFFAOYSA-N
- Ethylchlorooxo-acetate
- ethyl chloro(oxo)acetate
- ethyl chloroxoacetate
- Oxalic acid chloride ethyl ester
- S8B2T78QGR
- BBL027307
- STL371945
-
- MDL： MFCD00000706
- Inchi： 1S/C4H5ClO3/c1-2-8-4(7)3(5)6/h2H2,1H3
- InChI Key： OWZFULPEVHKEKS-UHFFFAOYSA-N
- SMILES： ClC(C(=O)OCC)=O
- BRN： 506725
Computed Properties
- Exact Mass: 135.99300
- Monoisotopic Mass: 135.993
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 8
- Rotatable Bond Count: 3
- Complexity: 110
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 43.4A^2
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 1.4
Experimental Properties
- Color/Form: colorless liquid
- Density: 1.222?g/mL?at 25?°C(lit.)
- Melting Point: 135℃
- Boiling Point: 135?°C(lit.)
- Flash Point: Fahrenheit: 105.8 ° f
Celsius: 41 ° c - Refractive Index: n20/D 1.416(lit.)
- Water Partition Coefficient: Slightly miscible with water.
- PSA: 43.37000
- LogP: 0.31490
- Sensitiveness: Moisture Sensitive
- Solubility: Uncertain
ethyl 2-chloro-2-oxo-acetate Security Information
-
Symbol:
- Prompt：dangerous
- Signal Word：Danger
- Hazard Statement： H226,H314
- Warning Statement： P280,P305+P351+P338,P310
- Hazardous Material transportation number：2920
- WGK Germany：3
- Hazard Category Code： 10-34-37
- Safety Instruction： S8-S45-S36/37/39-S26-S16
-
Hazardous Material Identification：
- HazardClass：8 (3)
- PackingGroup：II
- TSCA：Yes
- Storage Condition：Store at room temperature
- Packing Group：II
- Hazard Level：8
- Risk Phrases：R10; R34; R37
- Packing Group：II
- Safety Term：8
ethyl 2-chloro-2-oxo-acetate Customs Data
- HS CODE：29171990
- Customs Data：
China Customs Code:
2918300090Overview:
2918300090 Other aldehydes or ketones without other oxy carboxylic acids(Including anhydrides\Acyl halide\Peroxides, peroxyacids and derivatives of this tax number). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:6.5%.General tariff:30.0%
ethyl 2-chloro-2-oxo-acetate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | C1066-100g |
ethyl 2-chloro-2-oxo-acetate |
4755-77-5 | 98.0%(T) | 100g |
￥990.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | C1066-500g |
ethyl 2-chloro-2-oxo-acetate |
4755-77-5 | 98.0%(T) | 500g |
￥2990.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | C1066-25g |
ethyl 2-chloro-2-oxo-acetate |
4755-77-5 | 98.0%(T) | 25g |
￥320.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | E002A-500g |
ethyl 2-chloro-2-oxo-acetate |
4755-77-5 | 98% | 500g |
￥623.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | E002A-100g |
ethyl 2-chloro-2-oxo-acetate |
4755-77-5 | 98% | 100g |
￥198.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | E002A-25g |
ethyl 2-chloro-2-oxo-acetate |
4755-77-5 | 98% | 25g |
￥84.0 | 2022-05-30 | |
| Fluorochem | 024489-25g |
Ethyl oxalyl chloride |
4755-77-5 | 98% | 25g |
￡11.00 | 2022-03-01 | |
| Fluorochem | 024489-100g |
Ethyl oxalyl chloride |
4755-77-5 | 98% | 100g |
￡26.00 | 2022-03-01 | |
| Fluorochem | 024489-500g |
Ethyl oxalyl chloride |
4755-77-5 | 98% | 500g |
￡90.00 | 2022-03-01 | |
| Fluorochem | 024489-1kg |
Ethyl oxalyl chloride |
4755-77-5 | 98% | 1kg |
￡155.00 | 2022-03-01 |
ethyl 2-chloro-2-oxo-acetate Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:4755-77-5)Ethyl chlorooxoacetate
Order Number:sfd2940
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:33
Price ($):discuss personally
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:4755-77-5)Ethyl oxalyl monochloride
Order Number:LE2576
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:42
Price ($):discuss personally
Email:[email protected]
ethyl 2-chloro-2-oxo-acetate Related Literature
-
Rulin Zhao,Zhenqiu Hong,Bei Wang,James Kempson,Lyndon Cornelius,Jianqing Li,Yi-Xin Li,Arvind Mathur Org. Biomol. Chem. 2022 20 9746
-
Jia-Fei Poon,John Patrick Alao,Per Sunnerhagen,Peter Dinér Org. Biomol. Chem. 2013 11 4526
-
Yinliang Qi,Le Xu,Zhiwei Li,Ping Gong,Tao Hu,Bixi Yin,Mingze Qin,Yajing Liu,Yanfang Zhao,Yunlei Hou New J. Chem. 2020 44 16477
-
Renata Riva,Luca Banfi,Andrea Basso,Paola Zito Org. Biomol. Chem. 2011 9 2107
-
Chenchen Li,Huanrui Zhang,Samuel Mirie,Jiawei Peng,Mian Cai,Xiao Wang,Zhenggang Lan,Xiaobo Wan Org. Chem. Front. 2018 5 442
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