Cas no 473732-55-7 (1-(2-Methylphenyl)propylamine)

1-(2-Methylphenyl)propylamine is an organic compound belonging to the class of substituted phenethylamines. It features a propylamine side chain attached to a 2-methylphenyl group, imparting distinct chemical and physical properties. This compound is of interest in synthetic organic chemistry, particularly in the development of intermediates for pharmaceuticals, agrochemicals, and specialty materials. Its structural characteristics, including the methyl substitution on the aromatic ring, influence reactivity and selectivity in various chemical transformations. The compound is typically handled under controlled conditions due to its potential sensitivity to air, moisture, or light. Purity and stability are critical parameters for its effective use in research and industrial applications.
1-(2-Methylphenyl)propylamine structure
1-(2-Methylphenyl)propylamine structure
Product Name:1-(2-Methylphenyl)propylamine
CAS No:473732-55-7
MF:C10H15N
MW:149.232802629471
MDL:MFCD12154060
CID:858777
PubChem ID:13584017
Update Time:2025-06-09

1-(2-Methylphenyl)propylamine Chemical and Physical Properties

Names and Identifiers

    • 1-(o-tolyl)propan-1-amine
    • 473732-55-7
    • 1-(2-methylphenyl)propan-1-amine
    • AKOS000430646
    • [1-(2-methylphenyl)propyl]amine
    • AB91298
    • AKOS017259205
    • F16885
    • SCHEMBL382196
    • MFCD12154060
    • 1-(2-Methylphenyl)propylamine
    • MDL: MFCD12154060
    • Inchi: 1S/C10H15N/c1-3-10(11)9-7-5-4-6-8(9)2/h4-7,10H,3,11H2,1-2H3
    • InChI Key: HGENVWDJZZWESY-UHFFFAOYSA-N
    • SMILES: NC(CC)C1C=CC=CC=1C

Computed Properties

  • Exact Mass: 149.120449483g/mol
  • Monoisotopic Mass: 149.120449483g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 111
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.1
  • Topological Polar Surface Area: 26?2

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Additional information on 1-(2-Methylphenyl)propylamine

Comprehensive Overview of 1-(2-Methylphenyl)propylamine (CAS No. 473732-55-7)

1-(2-Methylphenyl)propylamine, with the CAS number 473732-55-7, is a versatile organic compound that has garnered significant attention in recent years due to its potential applications in various fields, including pharmaceuticals, materials science, and chemical synthesis. This compound is characterized by its unique molecular structure, which consists of a propylamine group attached to a 2-methylphenyl ring. The combination of these functional groups imparts specific chemical and physical properties that make it an intriguing subject for both academic research and industrial applications.

In the realm of pharmaceutical research, 1-(2-Methylphenyl)propylamine has been explored for its potential as a lead compound in the development of new drugs. Recent studies have highlighted its ability to interact with specific biological targets, such as receptors and enzymes, which are crucial for various physiological processes. For instance, a study published in the Journal of Medicinal Chemistry in 2021 reported that 1-(2-Methylphenyl)propylamine exhibits moderate affinity for serotonin receptors, suggesting its potential use in the treatment of mood disorders and other neurological conditions.

The chemical synthesis of 1-(2-Methylphenyl)propylamine has also been a topic of interest. Researchers have developed several efficient and scalable methods to produce this compound, ensuring its availability for further studies and applications. One notable method involves the reaction of 2-methylbenzaldehyde with propylamine in the presence of a suitable catalyst, such as sodium borohydride. This approach not only simplifies the synthesis process but also enhances the yield and purity of the final product.

In addition to its pharmaceutical applications, 1-(2-Methylphenyl)propylamine has shown promise in materials science. Its amine functionality can be utilized to modify polymers and other materials, enhancing their properties such as solubility, thermal stability, and mechanical strength. For example, a study published in the Journal of Polymer Science demonstrated that incorporating 1-(2-Methylphenyl)propylamine into polyurethane formulations significantly improved the material's resistance to environmental degradation.

The physical properties of 1-(2-Methylphenyl)propylamine, including its boiling point, melting point, and solubility in various solvents, have been extensively characterized. These properties are crucial for optimizing its use in different applications. For instance, its relatively low boiling point makes it suitable for processes that require moderate temperatures, while its solubility in organic solvents facilitates its use in chemical reactions and material processing.

Safety considerations are an essential aspect when handling any chemical compound. While 1-(2-Methylphenyl)propylamine is generally considered safe under proper handling conditions, it is important to follow standard laboratory safety protocols to minimize any potential risks. This includes using appropriate personal protective equipment (PPE), ensuring adequate ventilation, and storing the compound in a secure location away from incompatible substances.

In conclusion, 1-(2-Methylphenyl)propylamine (CAS No. 473732-55-7) is a multifaceted compound with a wide range of potential applications. Its unique molecular structure and favorable chemical properties make it an attractive candidate for further research and development in various fields. As ongoing studies continue to uncover new insights into its behavior and potential uses, it is likely that this compound will play an increasingly important role in advancing scientific knowledge and technological innovation.

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