Cas no 472805-74-6 (2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid)

2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid is a heterocyclic carboxylic acid derivative featuring a thiazole core substituted with a methoxyphenyl group at the 2-position and a methyl group at the 4-position. This compound is of interest in medicinal and synthetic chemistry due to its structural motif, which is commonly found in bioactive molecules. The presence of both the thiazole ring and carboxylic acid functionality enhances its utility as a versatile intermediate for further derivatization, particularly in the development of pharmaceuticals and agrochemicals. Its well-defined structure and reactivity make it suitable for applications in targeted synthesis and drug discovery research.
2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid structure
472805-74-6 structure
Product Name:2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid
CAS No:472805-74-6
MF:C12H11NO3S
MW:249.285641908646
MDL:MFCD06857926
CID:930824
PubChem ID:329819227
Update Time:2025-05-20

2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid Chemical and Physical Properties

Names and Identifiers

    • 2-(2-methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid
    • 4-METHYL-2-(2-METHOXYPHENYL)THIAZOLE-5-CARBOXYLICACID
    • F3284-7863
    • SCHEMBL3436652
    • 4-Methyl-2-(2-methoxyphenyl)thiazole-5-carboxylic acid
    • DB-195781
    • OTAVA-BB BB7020331256
    • 2-(2-methoxyphenyl)-4-methylthiazole-5-carboxylic acid
    • CS-0332111
    • 2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid, AldrichCPR
    • AKOS000273558
    • DTXSID60407213
    • 472805-74-6
    • MFCD06857926
    • 2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid
    • MDL: MFCD06857926
    • Inchi: 1S/C12H11NO3S/c1-7-10(12(14)15)17-11(13-7)8-5-3-4-6-9(8)16-2/h3-6H,1-2H3,(H,14,15)
    • InChI Key: INVCLUFEKIDXBW-UHFFFAOYSA-N
    • SMILES: S1C(C(=O)O)=C(C)N=C1C1C=CC=CC=1OC

Computed Properties

  • Exact Mass: 249.04600
  • Monoisotopic Mass: 249.04596439g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 3
  • Complexity: 287
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.8
  • Topological Polar Surface Area: 87.7?2

Experimental Properties

  • PSA: 87.66000
  • LogP: 2.82530

2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid Security Information

  • Symbol: GHS07
  • Signal Word:Warning
  • Hazard Statement: H302
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 22
  • Hazardous Material Identification: Xn

2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid Pricemore >>

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Additional information on 2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid

2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid: A Comprehensive Overview

2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid, also known by its CAS Registry Number 472805-74-6, is a compound of significant interest in the fields of organic chemistry, pharmacology, and materials science. This compound belongs to the class of thiazole derivatives, which have been extensively studied due to their diverse biological activities and potential applications in drug design. The structure of this compound is characterized by a thiazole ring system substituted with a methoxyphenyl group and a methyl group, along with a carboxylic acid moiety. These structural features contribute to its unique chemical properties and reactivity.

The synthesis of 2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid has been explored through various methodologies, including condensation reactions and cyclization processes. Recent advancements in synthetic chemistry have enabled the development of more efficient and environmentally friendly routes for its preparation. For instance, researchers have employed microwave-assisted synthesis to enhance reaction rates and selectivity, reducing the overall production time and cost. Such innovations highlight the importance of continuous improvement in synthetic strategies to meet the growing demand for this compound in both academic and industrial settings.

In terms of pharmacological applications, 2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid has demonstrated promising activity in several biological assays. Studies have shown that this compound exhibits potent anti-inflammatory and antioxidant properties, making it a potential candidate for the development of novel therapeutic agents. Furthermore, its ability to modulate key cellular pathways involved in neurodegenerative diseases has drawn attention from researchers in the field of neuroscience. Recent findings suggest that this compound may exert neuroprotective effects by inhibiting oxidative stress and reducing inflammation in neuronal cells.

Beyond its pharmacological applications, 2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid has also found utility in materials science. Its unique electronic properties make it a suitable candidate for use in organic electronics, such as organic light-emitting diodes (OLEDs) and field-effect transistors (FETs). Researchers have investigated its ability to act as an electron acceptor or donor in these devices, contributing to improved device performance. Additionally, its compatibility with various polymer matrices has led to its exploration as a component in advanced composite materials.

The environmental impact of 2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid is another area of growing interest. As industries increasingly prioritize sustainability, understanding the biodegradation and toxicity profiles of this compound becomes crucial. Recent studies have assessed its environmental fate under various conditions, revealing that it undergoes microbial degradation under aerobic conditions. However, further research is needed to fully characterize its long-term effects on ecosystems and develop strategies for safe disposal.

In conclusion, 2-(2-Methoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid, with its CAS number 472805-74-6, stands as a versatile compound with diverse applications across multiple disciplines. Its chemical properties, synthetic accessibility, biological activity, and material science potential underscore its significance in contemporary research. As advancements continue to unfold, this compound is poised to play an even greater role in shaping future innovations across various industries.

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