Cas no 4656-81-9 (tetrahexylammonium perchlorate)

Tetrahexylammonium perchlorate (THAP) is a quaternary ammonium salt with the chemical formula [N(C?H??)?]ClO?. It is primarily used as a phase-transfer catalyst (PTC) in organic synthesis due to its ability to facilitate reactions between immiscible phases. THAP exhibits high thermal stability and solubility in nonpolar solvents, making it suitable for applications in electrochemical systems and as an electrolyte additive. Its perchlorate anion contributes to strong oxidative properties, while the bulky tetrahexylammonium cation enhances lipophilicity, improving interfacial activity. THAP is valued for its efficiency in nucleophilic substitutions and polymerization reactions, offering consistent performance under varied conditions. Proper handling is essential due to its potential explosiveness when exposed to heat or shock.
tetrahexylammonium perchlorate structure
4656-81-9 structure
Product Name:tetrahexylammonium perchlorate
CAS No:4656-81-9
MF:C24H52ClNO4
MW:454.126987457275
CID:85112
PubChem ID:78388
Update Time:2025-10-15

tetrahexylammonium perchlorate Chemical and Physical Properties

Names and Identifiers

    • tetrahexylammonium perchlorate
    • Tetra-n-hexylammonium perchlorate
    • tetrahexylazanium,perchlorate
    • EINECS 225-095-8
    • n,n,n-trihexylhexan-1-aminiumperchlorate
    • perchlorate de tetrahexylammonium
    • Tetrahexylammoniumhydroxyd
    • MFCD00043185
    • SCHEMBL2099654
    • 4-chloro-5-(ethylthio)-2-phenylpyridazine-3(2h)-one
    • 4656-81-9
    • tetrahexylazanium;perchlorate
    • 1-Hexanaminium, N,N,N-trihexyl-, perchlorate (1:1)
    • DTXSID8063545
    • FT-0724845
    • 1-Hexanaminium, N,N,N-trihexyl-, perchlorate
    • NS00082944
    • RLCKPGXHGKSGOS-UHFFFAOYSA-M
    • MDL: MFCD00043185
    • Inchi: 1S/C24H52N.ClO4/c1-5-9-13-17-21-25(22-18-14-10-6-2,23-19-15-11-7-3)24-20-16-12-8-4;2-1(3,4)5/h5-24H2,1-4H3;/q+1;-1
    • InChI Key: IGMHKIXHRHQEIG-UHFFFAOYSA-N
    • SMILES: [Cl+3]([O-])([O-])([O-])[O-].[N+](CCCCCC)(CCCCCC)(CCCCCC)CCCCCC

Computed Properties

  • Exact Mass: 453.35800
  • Monoisotopic Mass: 453.358
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 30
  • Rotatable Bond Count: 20
  • Complexity: 291
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 74.3A^2

Experimental Properties

  • Color/Form: White crystals
  • Melting Point: 103-105?°C
  • Boiling Point: °Cat760mmHg
  • Flash Point: °C
  • Stability/Shelf Life: Stable. Strong oxidizer - do not store near combustible materials. Incompatible with reducing agents, organic materials. Heat-sensitive.
  • PSA: 74.27000
  • LogP: 8.33870
  • Solubility: Uncertain
  • Vapor Pressure: No data available

tetrahexylammonium perchlorate Security Information

tetrahexylammonium perchlorate Customs Data

  • HS CODE:2923900090
  • Customs Data:

    China Customs Code:

    2923900090

    Overview:

    2923900090 Other quaternary ammonium salts and quaternary ammonium bases.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:6.5%.general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2923900090 other quaternary ammonium salts and hydroxides.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:6.5%.General tariff:30.0%

tetrahexylammonium perchlorate Pricemore >>

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tetrahexylammonium perchlorate Related Literature

Additional information on tetrahexylammonium perchlorate

Introduction to Tetrahexylammonium Perchlorate (CAS No: 4656-81-9)

Tetrahexylammonium perchlorate, with the chemical formula C24H51NO4 and CAS number 4656-81-9, is a quaternary ammonium salt that has garnered significant attention in the field of pharmaceuticals, materials science, and catalysis. This compound, characterized by its long alkyl chain and perchlorate anion, exhibits unique physicochemical properties that make it a valuable additive in various industrial and research applications. The extensive hydrophobicity of its structure, coupled with the high electronegativity of the perchlorate ion, contributes to its versatility in solubilizing hydrophobic molecules and facilitating electrochemical processes.

The synthesis of Tetrahexylammonium perchlorate typically involves the reaction of tetrahexylammonium hydroxide with perchloric acid under controlled conditions. This process ensures high purity and yield, making it commercially viable for large-scale applications. The compound's stability under a wide range of temperatures and pH levels further enhances its utility in diverse environments. In pharmaceutical research, Tetrahexylammonium perchlorate has been explored as a potential excipient due to its ability to enhance drug solubility and improve bioavailability. Its compatibility with various drug molecules has led to studies investigating its role in formulating novel drug delivery systems.

Recent advancements in the application of Tetrahexylammonium perchlorate have highlighted its role in advanced material science. Specifically, researchers have leveraged its properties to develop novel liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs). The compound's ability to act as a stabilizing agent in liquid crystal formulations has improved the performance and longevity of these devices. Additionally, its use as a catalyst or co-catalyst in organic synthesis has shown promise in streamlining complex reactions, thereby reducing reaction times and improving yields.

In the realm of biomedicine, Tetrahexylammonium perchlorate has been investigated for its potential antimicrobial properties. Studies have demonstrated that it can disrupt bacterial cell membranes, leading to increased permeability and cell death. This mechanism has sparked interest in developing antimicrobial coatings for medical devices and surfaces. Furthermore, its compatibility with biological systems has prompted research into its use as a contrast agent in medical imaging techniques. The compound's ability to enhance image clarity while maintaining biocompatibility makes it a promising candidate for future medical applications.

The environmental impact of Tetrahexylammonium perchlorate is another critical area of study. While it is not classified as a hazardous substance under current regulations, its behavior in aquatic environments remains an area of concern. Research has focused on understanding its degradation pathways and potential effects on aquatic ecosystems. Efforts are underway to develop environmentally friendly alternatives or modifications to minimize any adverse impacts. These studies underscore the importance of sustainable chemistry practices in ensuring that compounds like Tetrahexylammonium perchlorate are used responsibly.

Future directions for research on Tetrahexylammonium perchlorate include exploring new synthetic routes that enhance efficiency and reduce waste. Additionally, investigating novel applications in energy storage and conversion systems is an emerging area of interest. Its ability to facilitate redox reactions makes it a candidate for use in batteries and supercapacitors. By integrating Tetrahexylammonium perchlorate into these systems, researchers aim to improve energy density and charge/discharge rates.

The regulatory landscape for Tetrahexylammonium perchlorate is continually evolving, reflecting both its benefits and challenges. Regulatory bodies are closely monitoring its use across different industries to ensure safety and efficacy. Compliance with existing guidelines is essential for manufacturers and researchers to maintain ethical standards while advancing scientific knowledge. As new applications emerge, ongoing dialogue between industry stakeholders and regulatory agencies will be crucial to address any emerging concerns.

In conclusion, Tetrahexylammonium perchlorate (CAS No: 4656-81-9) is a multifaceted compound with significant potential across multiple sectors. Its unique properties make it indispensable in pharmaceuticals, materials science, biomedicine, and environmental chemistry. As research continues to uncover new applications and refine existing ones, the importance of this compound will only grow. By staying at the forefront of innovation while adhering to ethical standards, scientists can harness the full potential of Tetrahexylammonium perchlorate for the betterment of society.

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