• 1. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
• 2. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 3. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
• 4. Exchanged ligands on the surface of a giant cluster: [(MoO3)176(H2O)63(CH3OH)17Hn](32 – n)–
  Chem. Commun., 1998, 1501-1502
• 5. Fe3O4/PEG-SO3H as a heterogeneous and magnetically-recyclable nanocatalyst for the oxidation of sulfides to sulfones or sulfoxides
  Saeideh Mirfakhraei,Malak Hekmati,Fereshteh Hosseini Eshbala,Hojat Veisi New J. Chem., 2018,42, 1757-1761

H-DL-MET(O)-OH (CAS No. 454-41-1): A Comprehensive Overview

H-DL-MET(O)-OH (CAS No. 454-41-1) is a versatile compound with significant applications in the fields of chemistry, biochemistry, and pharmaceutical research. This compound, also known as H-DL-Methionine (Oxidized), is a derivative of methionine, an essential amino acid that plays a crucial role in various biological processes. The oxidized form of methionine, H-DL-MET(O)-OH, has gained attention for its unique properties and potential therapeutic applications.

The chemical structure of H-DL-MET(O)-OH consists of a methionine backbone with an oxidized sulfur atom. This structural modification alters the chemical and biological properties of the molecule, making it a valuable tool in research and development. The compound is often used in studies related to protein structure and function, as well as in the development of novel therapeutic agents.

Recent advancements in the field have highlighted the importance of H-DL-MET(O)-OH in understanding the mechanisms of protein oxidation and its implications in various diseases. For instance, oxidative stress is a key factor in the pathogenesis of neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. Research has shown that the oxidized form of methionine can serve as a biomarker for oxidative stress, providing insights into the early stages of these conditions.

In addition to its role in disease biomarker research, H-DL-MET(O)-OH has been explored for its potential therapeutic applications. Studies have demonstrated that the compound can modulate cellular signaling pathways involved in inflammation and cell death. This property makes it a promising candidate for developing treatments for inflammatory diseases and conditions characterized by excessive cell death.

The synthesis and purification of H-DL-MET(O)-OH are well-documented processes that involve several steps to ensure high purity and stability. The compound can be synthesized through chemical oxidation of methionine or obtained through enzymatic methods. High-performance liquid chromatography (HPLC) is commonly used to purify and analyze the compound, ensuring its quality for research purposes.

One of the key challenges in working with H-DL-MET(O)-OH is maintaining its stability under different conditions. The oxidized sulfur atom is susceptible to further oxidation or reduction, which can affect the compound's properties and functionality. Therefore, careful handling and storage conditions are essential to preserve the integrity of the molecule.

In clinical settings, H-DL-MET(O)-OH has been used as a reference standard in assays designed to measure oxidative stress markers. Its well-characterized properties make it an ideal control substance for validating new analytical methods and ensuring the accuracy of results. This application has significant implications for diagnostic testing and personalized medicine.

The future prospects for H-DL-MET(O)-OH are promising, with ongoing research exploring its potential in various therapeutic areas. For example, studies are underway to investigate its role in modulating immune responses and its potential as an adjuvant in vaccine development. Additionally, there is growing interest in using H-DL-MET(O)-OH as a component in nutraceuticals and dietary supplements due to its antioxidant properties.

In conclusion, H-DL-MET(O)-OH (CAS No. 454-41-1) is a multifaceted compound with a wide range of applications in scientific research and pharmaceutical development. Its unique chemical structure and biological properties make it an important tool for understanding oxidative stress, developing new therapies, and advancing diagnostic techniques. As research continues to uncover new insights into its mechanisms and potential uses, the importance of this compound is likely to grow even further.

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