Cas no 454-14-8 (Cuscohygrine (Mixture of Diastereomers))

Cuscohygrine (Mixture of Diastereomers) is a tropane alkaloid naturally occurring in plants of the Solanaceae family. This compound is characterized by its bicyclic structure, incorporating a pyrrolidine and piperidine ring system. As a mixture of diastereomers, it offers versatility in research applications, particularly in the study of alkaloid biosynthesis and pharmacological activity. Cuscohygrine serves as a valuable reference standard in analytical chemistry, aiding in the identification and quantification of related alkaloids in plant extracts. Its well-defined chemical properties make it suitable for use in metabolic studies and as a precursor in synthetic organic chemistry. The product is typically supplied with high purity, ensuring reliable performance in experimental workflows.
Cuscohygrine (Mixture of Diastereomers) structure
454-14-8 structure
Product Name:Cuscohygrine (Mixture of Diastereomers)
CAS No:454-14-8
MF:C13H24N2O
MW:224.342463493347
CID:37494
PubChem ID:1201543
Update Time:2025-05-20

Cuscohygrine (Mixture of Diastereomers) Chemical and Physical Properties

Names and Identifiers

    • Cuscohygrine
    • 1,3-Bis[(2S)-1-methylpyrrolidin-2-yl]propan-2-one
    • Cuscohygrine (Mixture of Diastereomers)
    • Cuscohygrine (Mixture of Diastereomers)
    • Cuskhygrine
    • Hellaradine
    • Cuskhygrin
    • 2-PROPANONE, 1-((2R)-1-METHYL-2-PYRROLIDINYL)-3-((2S)-1-METHYL-2-PYRROLIDINYL)-, REL-
    • 1,3-bis(1-methylpyrrolidin-2-yl)acetone
    • DTXSID70894079
    • meso-Cuscohygrine
    • 1-[(2R)-1-methylpyrrolidin-2-yl]-3-[(2S)-1-methylpyrrolidin-2-yl]acetone
    • 1-[(2S)-1-methylpyrrolidin-2-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]propan-2-one
    • 2-Propanone, 1,3-bis(1-methyl-2-pyrrolidinyl)-, (R*,S*)-
    • CUSCOHYGRINE, MESO-
    • Bellaradin
    • CUSCOHYGRINE [WHO-DD]
    • 1-[(2R)-1-methylpyrrolidin-2-yl]-3-[(2S)-1-methylpyrrolidin-2-yl]propan-2-one
    • UNII-93FJ3823VL
    • NS00094169
    • CHEBI:27920
    • J-520125
    • (R*,S*)-1,3-Bis(1-methyl-2-pyrrolidinyl)-2-propanone
    • 454-14-8
    • SCHEMBL336171
    • CUSCOHYGRINE [MI]
    • 1-((R)-1-Methylpyrrolidin-2-yl)-3-((S)-1-methylpyrrolidin-2-yl)propan-2-one
    • Q3007886
    • 93FJ3823VL
    • Bellaradine
    • SCHEMBL336170
    • ZEBIACKKLGVLFZ-UHFFFAOYSA-N
    • FT-0665235
    • FT-0665236
    • C06521
    • 1,3-bis-(1-methylpyrrolidin-2yl)-propan-2-one
    • 1,3-Bis(1-methyl-2-pyrrolidinyl)-2-propanone, 9CI
    • Cuscohygrine(Mixture of Diastereomers)
    • G83454
    • 2-Propanone,1-[(2R)-1-methyl-2-pyrrolidinyl]-3-[(2S)-1-methyl-2-pyrrolidinyl]-, rel-
    • 1-((2R)-1-methylpyrrolidin-2-yl)-3-((2S)-1-methylpyrrolidin-2-yl)propan-2-one
    • 1-((2S)-1-methylpyrrolidin-2-yl)-3-((2R)-1-methylpyrrolidin-2-yl)propan-2-one
    • 1-((2R)-1-methylpyrrolidin-2-yl)-3-((2S)-1-methylpyrrolidin-2-yl)acetone
    • DTXCID301324121
    • Inchi: 1S/C13H24N2O/c1-14-7-3-5-11(14)9-13(16)10-12-6-4-8-15(12)2/h11-12H,3-10H2,1-2H3/t11-,12+
    • InChI Key: ZEBIACKKLGVLFZ-TXEJJXNPSA-N
    • SMILES: O=C(C[C@H]1CCCN1C)C[C@@H]1CCCN1C

Computed Properties

  • Exact Mass: 224.18900
  • Monoisotopic Mass: 224.189
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 4
  • Complexity: 230
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 23.6A^2
  • XLogP3: 1

Experimental Properties

  • Density: d420 0.9733
  • Boiling Point: bp23 169-170°; bp14 152°; bp2 118-125°
  • Flash Point: 118.0±13.3 °C
  • Refractive Index: nD20 1.4832
  • Solubility: Chloroform, Ethyl Acetate, Methanol
  • Stability/Shelf Life: Solutions are unstable.
  • PSA: 23.55000
  • LogP: 1.39990
  • Vapor Pressure: 0.0±0.7 mmHg at 25°C

Cuscohygrine (Mixture of Diastereomers) Security Information

Cuscohygrine (Mixture of Diastereomers) Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Cuscohygrine (Mixture of Diastereomers) Pricemore >>

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Cuscohygrine (Mixture of Diastereomers) Related Literature

Additional information on Cuscohygrine (Mixture of Diastereomers)

Exploring Cuscohygrine (Mixture of Diastereomers): A Comprehensive Guide to CAS No. 454-14-8

Cuscohygrine (Mixture of Diastereomers), identified by its CAS No. 454-14-8, is a naturally occurring alkaloid with a unique chemical structure and diverse applications in research and industry. This compound, often found in plants of the Solanaceae family, has garnered significant attention due to its potential pharmacological properties and role in plant defense mechanisms. In this article, we delve into the molecular characteristics, sources, and contemporary relevance of Cuscohygrine, addressing common queries and emerging trends in the field.

The chemical structure of Cuscohygrine features a pyrrolidine ring system, which is typical of tropane alkaloids. Its mixture of diastereomers adds complexity to its stereochemistry, making it a subject of interest for synthetic chemists and pharmacologists. Researchers often explore its bioactivity, particularly its interactions with neurotransmitter systems, which could have implications for neurological studies. The compound's presence in traditional medicinal plants has also sparked curiosity about its historical uses and potential modern applications.

One of the most frequently asked questions about Cuscohygrine is its natural sources. It is primarily extracted from plants like Erythroxylum coca and other members of the Solanaceae family. These plants have been studied for their alkaloid content, with Cuscohygrine often co-occurring with other well-known compounds. The extraction and purification processes are critical for obtaining high-purity samples, which are essential for accurate research outcomes. Recent advancements in chromatographic techniques have improved the isolation of Cuscohygrine, enabling more precise studies.

In the context of current trends, the interest in natural products and plant-derived compounds has surged, driven by the demand for sustainable and eco-friendly alternatives in pharmaceuticals and cosmetics. Cuscohygrine fits into this narrative as a compound with potential biotechnological applications. For instance, its role in plant defense mechanisms against herbivores and pathogens has led to investigations into its use as a natural pesticide or antimicrobial agent. This aligns with the growing consumer preference for green chemistry solutions.

Another hot topic is the pharmacological potential of Cuscohygrine. While it is not as widely studied as some other alkaloids, preliminary research suggests it may have effects on the central nervous system. This has prompted questions about its possible therapeutic uses, such as in managing neurological disorders or as a precursor for drug development. However, rigorous clinical studies are needed to validate these hypotheses. The compound's mechanism of action remains an active area of research, with scientists employing computational modeling and in vitro assays to unravel its interactions.

From an industrial perspective, Cuscohygrine is valued for its role in chemical synthesis. Its unique structure makes it a useful intermediate for producing more complex molecules. Laboratories and manufacturers often seek high-quality Cuscohygrine for synthetic projects, emphasizing the need for reliable suppliers and standardized protocols. The compound's stability and reactivity are key considerations for these applications, and recent studies have focused on optimizing its handling and storage conditions.

For those interested in the analytical aspects of Cuscohygrine, techniques like mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy are indispensable. These methods allow for the precise identification and quantification of the compound, ensuring its purity and consistency in research settings. The development of high-throughput screening methods has further streamlined the analysis of Cuscohygrine and related alkaloids, catering to the needs of large-scale studies.

In summary, Cuscohygrine (Mixture of Diastereomers) (CAS No. 454-14-8) is a multifaceted compound with significant scientific and industrial relevance. Its natural origins, chemical properties, and potential applications make it a compelling subject for ongoing research. As the scientific community continues to explore its capabilities, Cuscohygrine may unlock new opportunities in pharmacology, agriculture, and beyond. Stay tuned for future breakthroughs in this dynamic field.

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