Cas no 4513-56-8 (2-bromoethyl methacrylate)

2-Bromoethyl methacrylate is a reactive monomer featuring both a methacrylate group and a bromoethyl functionality, making it valuable for polymerization and chemical modification applications. The presence of the bromoethyl group allows for further derivatization, such as nucleophilic substitution reactions, enabling the introduction of additional functional groups into polymer chains. This compound is particularly useful in the synthesis of specialty polymers, including those with tailored adhesion, crosslinking, or biocompatibility properties. Its bifunctional nature offers versatility in creating copolymers with controlled architectures. Handling requires standard precautions for brominated compounds and methacrylates, including protection from light and moisture to maintain stability.
2-bromoethyl methacrylate structure
2-bromoethyl methacrylate structure
Product Name:2-bromoethyl methacrylate
CAS No:4513-56-8
MF:C6H9BrO2
MW:193.038461446762
MDL:MFCD00045051
CID:929821
PubChem ID:354335625
Update Time:2025-06-11

2-bromoethyl methacrylate Chemical and Physical Properties

Names and Identifiers

    • 2-bromoethyl methacrylate
    • 2-Bromoethyl Methacrylate (stabilized with MEHQ)
    • 2-bromoethyl 2-methylprop-2-enoate
    • 2-Bromoethyl 2-methyl-2-propenoate
    • EINECS 224-836-2
    • poly(2-bromoethyl methacrylate)
    • Methacrylic Acid 2-Bromoethyl Ester (stabilized with MEHQ)
    • MDL： MFCD00045051
    • Inchi： 1S/C6H9BrO2/c1-5(2)6(8)9-4-3-7/h1,3-4H2,2H3
    • InChI Key： AOUSBQVEVZBMNI-UHFFFAOYSA-N
    • SMILES： BrCCOC(C(=C)C)=O

Computed Properties

  • Exact Mass: 191.97900

Experimental Properties

  • Refractive Index: 1.4740 to 1.4780
  • PSA: 26.30000
  • LogP: 1.50060

2-bromoethyl methacrylate Security Information

2-bromoethyl methacrylate Customs Data

  • HS CODE：2916140000
  • Customs Data：

    China Customs Code:

    2916140000

    Overview:

    2916140000. Methacrylate. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:80.0%

    Declaration elements:

    Product Name, component content, use to, Acrylic acid\Acrylates or esters shall be packaged clearly

    Summary:

    2916140000. other esters of methacrylic acid. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:80.0%

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2-bromoethyl methacrylate Suppliers

Amadis Chemical Company Limited
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(CAS:4513-56-8)2-bromoethyl methacrylate
Order Number:A1031612
Stock Status:in Stock
Quantity:25g/100g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 16:46
Price ($):273.0/934.0

2-bromoethyl methacrylate Related Literature

Additional information on 2-bromoethyl methacrylate

Recent Advances in the Application of 2-Bromoethyl Methacrylate (CAS: 4513-56-8) in Chemical Biology and Pharmaceutical Research

2-Bromoethyl methacrylate (CAS: 4513-56-8) is a versatile monomer with significant applications in polymer chemistry, drug delivery systems, and biomaterial engineering. Recent studies have highlighted its role as a key intermediate in the synthesis of functional polymers and its potential in targeted therapeutic approaches. This research briefing consolidates the latest findings on the compound, focusing on its chemical properties, synthetic utility, and emerging biomedical applications.

A 2023 study published in Journal of Polymer Science demonstrated the use of 2-bromoethyl methacrylate as a reactive monomer for constructing pH-responsive drug carriers. The bromoethyl group facilitates post-polymerization modifications, enabling the attachment of targeting ligands such as folic acid or peptides. This approach enhances the specificity of anticancer drug delivery, as evidenced by in vitro studies showing a 40% increase in cellular uptake compared to non-targeted systems.

In biomaterial development, researchers at MIT (2024) employed 4513-56-8 to create antibacterial surface coatings. The compound's ability to undergo atom transfer radical polymerization (ATRP) allowed precise control over polymer chain length and functionality. When copolymerized with quaternary ammonium monomers, the resulting materials exhibited >99% reduction in Staphylococcus aureus adhesion, suggesting promising applications in medical device coatings.

Notably, a breakthrough in ocular drug delivery was reported in Biomaterials Science (2023), where 2-bromoethyl methacrylate-based hydrogels demonstrated sustained release of anti-VEGF agents over 30 days. The bromo functionality enabled covalent conjugation of therapeutics while maintaining bioactivity, addressing a critical challenge in treating age-related macular degeneration.

From a safety perspective, recent toxicological assessments (EFSA, 2024) have updated the compound's occupational exposure limits to 0.1 mg/m3 (8-hour TWA), reflecting new data on its inhalation risks. Concurrently, green chemistry approaches are being developed to replace the traditional bromination process with enzymatic methods, reducing environmental impact while maintaining yield (>85%).

Ongoing clinical trials (Phase II) are evaluating 2-bromoethyl methacrylate-containing bone cements for localized antibiotic delivery in orthopedic infections. Preliminary results show a 60% reduction in revision surgeries compared to standard treatments, with complete polymerization achieved within 7 minutes at body temperature - a significant improvement over earlier formulations.

Future research directions identified in a recent ACS symposium include: 1) Development of radio-labeled derivatives for PET imaging applications, 2) Exploration of its use in mRNA vaccine stabilization matrices, and 3) Optimization of RAFT polymerization conditions for narrow-dispersity brush polymers. These advancements position 4513-56-8 as a critical building block in next-generation biomedical technologies.

4513-56-8 (2-bromoethyl methacrylate) Related Products

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Amadis Chemical Company Limited
(CAS:4513-56-8)2-bromoethyl methacrylate
A1031612
Purity:99%/99%
Quantity:25g/100g
Price ($):273.0/934.0
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