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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acid esters
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acid esters

Methyl 4-hydrazinobenzoate (CAS No. 4510-12-7): An Overview of Its Properties, Applications, and Recent Research

Methyl 4-hydrazinobenzoate (CAS No. 4510-12-7) is a versatile organic compound with a wide range of applications in the fields of chemistry, biology, and pharmaceuticals. This compound, also known as 4-hydrazinobenzoic acid methyl ester, has gained significant attention due to its unique chemical structure and potential in various scientific and industrial processes.

The chemical formula of Methyl 4-hydrazinobenzoate is C₈H₉N₃O₂. It is a white crystalline solid with a melting point of approximately 168-170°C. The compound is soluble in common organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), but it has limited solubility in water. These physical properties make it suitable for various synthetic and analytical applications.

In the realm of organic synthesis, Methyl 4-hydrazinobenzoate serves as an important intermediate in the preparation of more complex molecules. Its hydrazine functionality can undergo a variety of reactions, including condensation with aldehydes and ketones to form hydrazones, which are valuable intermediates in the synthesis of pharmaceuticals and agrochemicals. Additionally, the ester group can be hydrolyzed to yield the corresponding carboxylic acid, which can further participate in amide formation or other functional group transformations.

One of the key areas where Methyl 4-hydrazinobenzoate has shown promise is in the development of new pharmaceutical agents. Recent research has focused on its potential as a building block for the synthesis of antiviral and anticancer drugs. For instance, a study published in the Journal of Medicinal Chemistry reported the synthesis of a series of derivatives from Methyl 4-hydrazinobenzoate, which exhibited potent antiviral activity against several strains of influenza virus. Another study in the Bioorganic & Medicinal Chemistry Letters highlighted the use of this compound as a precursor for novel anticancer agents that target specific cellular pathways involved in tumor growth.

Beyond pharmaceutical applications, Methyl 4-hydrazinobenzoate has also found use in materials science. Its ability to form stable complexes with metal ions makes it a valuable ligand in coordination chemistry. Research in this area has explored its potential for developing new catalysts and functional materials. For example, a study published in the Inorganic Chemistry Communications demonstrated the synthesis of metal-organic frameworks (MOFs) using Methyl 4-hydrazinobenzoate as a linker molecule, resulting in materials with high surface areas and tunable pore sizes, suitable for gas storage and separation applications.

The environmental impact of chemical compounds is an important consideration in their development and application. Studies have shown that Methyl 4-hydrazinobenzoate exhibits low toxicity and environmental persistence when used under controlled conditions. However, proper handling and disposal practices are essential to minimize any potential risks. Researchers continue to investigate ways to improve the sustainability and eco-friendliness of processes involving this compound.

In conclusion, Methyl 4-hydrazinobenzoate (CAS No. 4510-12-7) is a multifaceted compound with significant potential across various scientific disciplines. Its unique chemical properties make it an invaluable tool for synthetic chemists, pharmaceutical researchers, and materials scientists alike. As ongoing research continues to uncover new applications and optimize existing ones, the importance of this compound is likely to grow even further.

• 473575-39-2(3-HYDRAZINO-BENZOIC ACID METHYL ESTER)
• 90556-87-9(3-Hydrazinobenzoic Acid Ethyl Ester)
• 14685-90-6(Ethyl 4-hydrazinylbenzoate)
• 830326-24-4(Methyl 3-hydrazinyl-4-methylbenzoate)
• 102536-01-6(Benzoic acid, 3-(2-phenylhydrazino)-, ethyl ester)
• 1260802-89-8(6-hydrazino-naphthalene-1-carboxylic acid methyl ester)
• 6296-89-5(Methyl 4-hydrazinylbenzoate Hydrochloride)
• 102536-02-7(Benzoic acid, 4-(2-phenylhydrazino)-, ethyl ester)
• 139718-89-1(Benzoic acid, 4-(2-formylhydrazino)-, methyl ester (9CI))
• 40566-85-6(Ethyl 4-hydrazinylbenzoate hydrochloride)