Cas no 4484-74-6 (Benzene,1-(iodomethyl)-4-methyl-)

Benzene,1-(iodomethyl)-4-methyl- is a halogenated aromatic compound characterized by the presence of an iodomethyl group and a methyl group on a benzene ring. This structure makes it a valuable intermediate in organic synthesis, particularly in cross-coupling reactions and nucleophilic substitutions due to the reactivity of the iodine moiety. Its stability and well-defined reactivity profile facilitate precise functionalization in pharmaceutical and agrochemical applications. The compound’s purity and consistent performance are critical for reproducibility in research and industrial processes. Proper handling is required due to its light sensitivity and potential volatility. Storage under inert conditions is recommended to maintain integrity.
Benzene,1-(iodomethyl)-4-methyl- structure
4484-74-6 structure
Product Name:Benzene,1-(iodomethyl)-4-methyl-
CAS No:4484-74-6
MF:C8H9I
MW:232.061534643173
CID:333075
PubChem ID:245144
Update Time:2025-06-14

Benzene,1-(iodomethyl)-4-methyl- Chemical and Physical Properties

Names and Identifiers

    • Benzene,1-(iodomethyl)-4-methyl-
    • 1-(iodomethyl)-4-methylbenzene
    • 1-IODOMETHYL-4-METHYLBENZENE
    • AC1L6F9B
    • AC1Q4PQR
    • CTK4I8488
    • KST-1B5227
    • NSC56730
    • SureCN687371
    • p-Xylyljodid
    • NSC 56730
    • NSC-56730
    • DTXSID40288587
    • AKOS014116548
    • 4484-74-6
    • SCHEMBL687371
    • Inchi: 1S/C8H9I/c1-7-2-4-8(6-9)5-3-7/h2-5H,6H2,1H3
    • InChI Key: YVJQXZQIGSNYKS-UHFFFAOYSA-N
    • SMILES: ICC1C=CC(C)=CC=1

Computed Properties

  • Exact Mass: 231.97447
  • Monoisotopic Mass: 231.975
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 1
  • Complexity: 72.6
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.3
  • Topological Polar Surface Area: 0?2

Experimental Properties

  • Density: 1.647
  • Boiling Point: 237.5°C at 760 mmHg
  • Flash Point: 104.4°C
  • Refractive Index: 1.612
  • PSA: 0
  • LogP: 2.93000

Benzene,1-(iodomethyl)-4-methyl- Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1687132-1g
1-(Iodomethyl)-4-methylbenzene
4484-74-6 98%
1g
¥8890.00 2024-05-13
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1687132-5g
1-(Iodomethyl)-4-methylbenzene
4484-74-6 98%
5g
¥23299.00 2024-05-13

Additional information on Benzene,1-(iodomethyl)-4-methyl-

Comprehensive Overview of Benzene,1-(iodomethyl)-4-methyl- (CAS No. 4484-74-6): Properties, Applications, and Industry Insights

Benzene,1-(iodomethyl)-4-methyl- (CAS No. 4484-74-6) is a specialized organic compound that has garnered significant attention in synthetic chemistry and material science. This halogenated aromatic derivative, also referred to as 4-Methylbenzyl iodide, plays a pivotal role in advanced chemical synthesis due to its unique reactivity profile. Researchers and industry professionals frequently search for terms like "synthesis of 4-Methylbenzyl iodide," "Benzene,1-(iodomethyl)-4-methyl- applications," and "CAS 4484-74-6 safety data," reflecting its relevance in both academic and industrial settings.

The molecular structure of Benzene,1-(iodomethyl)-4-methyl- features a benzene ring substituted with an iodomethyl group and a methyl group at the 1- and 4-positions, respectively. This arrangement confers distinct electrophilic properties, making it valuable for C-C bond formation reactions such as alkylations and cross-coupling processes. Recent studies highlight its utility in pharmaceutical intermediates, where queries like "iodomethyl benzene derivatives in drug discovery" trend in scientific databases. The compound’s high purity grade (≥98%) is often emphasized in supplier catalogs, addressing the demand for reliable reagents in precision chemistry.

From an environmental and regulatory perspective, Benzene,1-(iodomethyl)-4-methyl- is subject to standard handling protocols for halogenated compounds. Searches for "green chemistry alternatives for iodomethyl benzene" indicate growing interest in sustainable synthesis methods. Innovations in catalytic systems, such as palladium-mediated reactions, aim to minimize waste generation while maintaining yield efficiency—a topic frequently discussed in ACS (American Chemical Society) publications.

In material science, this compound serves as a precursor for liquid crystals and advanced polymers. The keyword "4-Methylbenzyl iodide in OLED materials" reflects emerging applications in optoelectronics. Its compatibility with Grignard reagents and organolithium compounds further expands its versatility, as noted in patents filed by major chemical enterprises. Analytical techniques like GC-MS and NMR are routinely employed to verify its purity, with users often seeking "CAS 4484-74-6 spectral data" for quality control.

The global market for Benzene,1-(iodomethyl)-4-methyl- is influenced by trends in specialty chemicals and R&D investments. Regions with robust pharmaceutical sectors, such as North America and Asia-Pacific, dominate procurement. Suppliers increasingly optimize SEO content around terms like "buy 4-Methylbenzyl iodide online" and "high-purity CAS 4484-74-6 suppliers" to capture B2B traffic. Storage recommendations typically emphasize protection from light and moisture, aligning with industry-standard practices for iodo-organic compounds.

Future research directions may explore its role in click chemistry and bioconjugation, areas gaining traction in biomedical engineering. As synthetic methodologies evolve, Benzene,1-(iodomethyl)-4-methyl- is poised to remain a critical building block—addressing both current industrial needs and next-generation innovations.

Recommended suppliers
PRIBOLAB PTE.LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
PRIBOLAB PTE.LTD
Zhengzhou Baoyu Pharmaceutical Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Zhengzhou Baoyu Pharmaceutical Co., Ltd.
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
上海帛亦醫(yī)藥科技有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shandong Feiyang Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Feiyang Chemical Co., Ltd