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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Benzofurans Benzofuranones
• Material Chemicals Colorants and Pigments Dyes
• Material Chemicals Colorants and Pigments

Chlorophenol Red: Chemical Profile and Recent Applications in Biomedical Research

Chlorophenol Red, a compound with the chemical formula C?H?Cl?O? and a CAS number of 4430-20-0, is a widely recognized chemical entity in the field of biomedical research. This compound, characterized by its red coloration when dissolved in aqueous solutions, has garnered significant attention due to its versatile applications in analytical chemistry, molecular biology, and pharmacological studies. The unique structural and functional properties of Chlorophenol Red make it an invaluable tool for researchers exploring various biochemical pathways and therapeutic interventions.

The molecular structure of Chlorophenol Red consists of a phenol ring substituted with two chlorine atoms and a carboxylic acid group. This configuration imparts distinct chemical reactivity, enabling the compound to participate in a wide range of biochemical interactions. The presence of the hydroxyl group and the electron-withdrawing chlorine atoms enhances its solubility in polar solvents, making it an excellent candidate for use in solution-based assays and experiments.

In recent years, Chlorophenol Red has been extensively utilized as a pH indicator in various biomedical applications. Its color transition range, typically from yellow to red, spans pH levels from 6.8 to 8.2, making it particularly useful for monitoring acid-base equilibrium in cellular environments. This property has been leveraged in studies investigating the effects of environmental stressors on cellular pH, as well as in the development of novel drug delivery systems that rely on pH-sensitive mechanisms.

Moreover, the compound has found application in the field of enzyme kinetics and protein binding studies. Researchers have employed Chlorophenol Red as a fluorescent probe to study the interaction between enzymes and their substrates. Its ability to emit fluorescence upon binding to specific biomolecules has made it a valuable tool for high-throughput screening assays aimed at identifying novel enzyme inhibitors. These inhibitors have potential therapeutic implications in treating various metabolic disorders and infectious diseases.

Recent advancements in biomedical research have highlighted the role of Chlorophenol Red in cellular signaling pathways. Studies have demonstrated its ability to modulate intracellular signaling cascades by interacting with specific receptors and ion channels. This has opened up new avenues for investigating the molecular mechanisms underlying diseases such as cancer, neurodegenerative disorders, and autoimmune conditions. The compound's ability to influence cellular signaling without exhibiting significant toxicity makes it an attractive candidate for further exploration in drug discovery efforts.

The analytical chemistry community has also benefited from the use of Chlorophenol Red as an internal standard or reference compound. Its well-characterized spectroscopic properties allow for accurate quantification of other analytes in complex mixtures. This has been particularly useful in metabolomics studies, where researchers aim to identify and quantify small molecules involved in metabolic pathways. The precision and reliability offered by Chlorophenol Red have contributed to advancements in our understanding of metabolic diseases and their treatment strategies.

In conclusion, Chlorophenol Red (CAS no. 4430-20-0) is a multifaceted compound with significant applications across various domains of biomedical research. Its unique chemical properties make it an indispensable tool for studying pH dynamics, enzyme kinetics, protein interactions, and cellular signaling pathways. As research continues to evolve, the versatility of Chlorophenol Red is likely to be further exploited, leading to new insights into disease mechanisms and innovative therapeutic approaches.

• 2303-01-7(m-Cresol purple)
• 2553-71-1(Bromochlorophenol blue)
• 115-41-3(Pyrocatechol violet)
• 1733-12-6(3,3-bis(4-hydroxy-3-methylphenyl)-3H-2,1lambda6-benzoxathiole-1,1-dione)
• 125-31-5(Xylenol Blue)
• 4430-24-4(Iodophenol blue)
• 123333-64-2(Chlorophenol Red Sodium Salt)
• 62625-29-0(Cresol Red Sodium Salt)
• 34487-61-1(Phenol Red sodium salt)
• 143-74-8(Phenol red)