Cas no 4403-84-3 ((4-aminophenyl)methanesulfonamide)

(4-Aminophenyl)methanesulfonamide is a sulfonamide derivative characterized by the presence of both an aromatic amine and a methanesulfonamide functional group. This compound serves as a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its reactive amine group allows for further functionalization, enabling the synthesis of more complex molecules. The sulfonamide moiety enhances stability and may contribute to biological activity, making it valuable in medicinal chemistry research. The compound exhibits moderate solubility in polar organic solvents, facilitating its use in various reaction conditions. Its well-defined structure and consistent purity make it a reliable building block for research applications requiring precise molecular modifications.

(4-aminophenyl)methanesulfonamide structure

4403-84-3 structure

Product Name:(4-aminophenyl)methanesulfonamide

CAS No:4403-84-3

MF:C₇H₁₀N₂O₂S

MW:186.231500148773

MDL:MFCD08436681

CID:929305

PubChem ID:10821407

Update Time:2025-05-19

(4-aminophenyl)methanesulfonamide Chemical and Physical Properties

Names and Identifiers

- 1-(4-AMINOPHENYL)METHANESULFONAMIDE
- (4-aminophenyl)methanesulfonamide
- 4-aminoBenzenemethanesulfonamide
- 4-Aminobenzenemethanesulphonamide
- DTXSID70445328
- EN300-27340
- (4-amino-phenyl)-methanesulfonamide
- Z235340045
- SCHEMBL2984207
- 4403-84-3
- 4-Amino-benzylsulfonamide
- 4-aminophenylmethanesulfonamide
- Benzenemethanesulfonamide, 4-amino-
- DA-21392
- CS-0160041
- BS-13643
- E79120
- 1-(4-aminophenyl)methane-sulfonamide
- 4-aminophenylmethane sulfonamide
- AKOS008093189
- MFCD08436681
- MDL： MFCD08436681
- Inchi： 1S/C7H10N2O2S/c8-7-3-1-6(2-4-7)5-12(9,10)11/h1-4H,5,8H2,(H2,9,10,11)
- InChI Key： NTYOKQYEVIDMCY-UHFFFAOYSA-N
- SMILES： S(CC1C=CC(=CC=1)N)(N)(=O)=O

Computed Properties

Exact Mass: 186.0464
Monoisotopic Mass: 186.04629874g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Heavy Atom Count: 12
Rotatable Bond Count: 2
Complexity: 224
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: nothing
XLogP3: nothing
Topological Polar Surface Area: 94.6?2

Experimental Properties

Density: 1.4±0.1 g/cm3
Boiling Point: 425.4±47.0 °C at 760 mmHg
Flash Point: 211.1±29.3 °C
PSA: 86.18
Vapor Pressure: 0.0±1.0 mmHg at 25°C

(4-aminophenyl)methanesulfonamide Security Information

Signal Word：warning
Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Warning Statement： P264+P280+P305+P351+P338+P337+P313
Safety Instruction： H303+H313+H333
Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)

(4-aminophenyl)methanesulfonamide Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
TRC	A620618-10mg	(4-aminophenyl)methanesulfonamide	4403-84-3		10mg	$ 50.00	2022-06-07
TRC	A620618-50mg	(4-aminophenyl)methanesulfonamide	4403-84-3		50mg	$ 160.00	2022-06-07
TRC	A620618-100mg	(4-aminophenyl)methanesulfonamide	4403-84-3		100mg	$ 250.00	2022-06-07
abcr	AB523352-250 mg	(4-Aminophenyl)methanesulfonamide; .	4403-84-3		250mg	€565.00	2023-06-14
abcr	AB523352-1 g	(4-Aminophenyl)methanesulfonamide; .	4403-84-3		1g	€1069.00	2023-06-14
Enamine	EN300-27340-1g	(4-aminophenyl)methanesulfonamide	4403-84-3	95%	1g	$699.0	2023-09-10
Enamine	EN300-27340-5g	(4-aminophenyl)methanesulfonamide	4403-84-3	95%	5g	$2028.0	2023-09-10
Enamine	EN300-27340-10g	(4-aminophenyl)methanesulfonamide	4403-84-3	95%	10g	$3007.0	2023-09-10
Enamine	EN300-27340-0.05g	(4-aminophenyl)methanesulfonamide	4403-84-3	95.0%	0.05g	$53.0	2025-03-21
Enamine	EN300-27340-0.1g	(4-aminophenyl)methanesulfonamide	4403-84-3	95.0%	0.1g	$83.0	2025-03-21

(4-aminophenyl)methanesulfonamide Suppliers

Amadis Chemical Company Limited

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Audited Supplier

(CAS:4403-84-3)(4-aminophenyl)methanesulfonamide

Order Number:A1160339

Stock Status:in Stock

Quantity:1g

Purity:99%

Pricing Information Last Updated:Thursday, 29 August 2024 23:59

Price ($):229.0

Email:[email protected]

Product Official Link

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Related Categories

Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Sulfanilides

Additional information on (4-aminophenyl)methanesulfonamide

(4-Aminophenyl)Methanesulfonamide (CAS No: 4403-84-3)

(4-Aminophenyl)Methanesulfonamide is a compound with the CAS registry number 4403-84-3, which is widely recognized in the field of organic chemistry and pharmaceutical research. This compound, also referred to as 4-amino-N-methylbenzenesulfonamide, has garnered significant attention due to its potential applications in drug development and its unique chemical properties.

The molecular formula of (4-Aminophenyl)Methanesulfonamide is C7H9N3O2S, with a molecular weight of 199.21 g/mol. Its structure consists of a sulfonamide group attached to a methyl group and an amino-substituted phenyl ring. This arrangement imparts the compound with both hydrophilic and hydrophobic characteristics, making it suitable for various chemical reactions and biological applications.

Recent studies have highlighted the role of (4-Aminophenyl)Methanesulfonamide in medicinal chemistry, particularly in the design of bioactive molecules. Researchers have explored its potential as a precursor for synthesizing more complex structures with therapeutic properties. For instance, modifications to the sulfonamide group have been shown to enhance the compound's bioavailability and pharmacokinetic profiles.

In terms of synthesis, (4-Aminophenyl)Methanesulfonamide can be prepared through a variety of methods, including nucleophilic aromatic substitution and coupling reactions. These methods have been optimized in recent years to improve yield and purity, making the compound more accessible for large-scale production.

The compound has also been investigated for its role in enzyme inhibition and receptor binding studies. Preliminary findings suggest that it may serve as a lead compound for developing novel drugs targeting specific biological pathways. Its ability to interact with key enzymes involved in inflammatory processes has positioned it as a promising candidate in anti-inflammatory drug discovery.

Moreover, advancements in computational chemistry have enabled researchers to predict the compound's behavior under various conditions. Molecular docking studies have revealed potential binding modes with therapeutic targets, providing insights into its mechanism of action at the molecular level.

In conclusion, (4-Aminophenyl)Methanesulfonamide (CAS No: 4403-84-3) stands out as a versatile compound with significant potential in pharmaceutical research and development. Its unique chemical structure, combined with recent advancements in synthesis and application studies, underscores its importance in modern drug discovery efforts.

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