Cas no 439918-59-9 ((R)-2-Pyrrolidineacetic acid Hydrochloride)
(R)-2-Pyrrolidineacetic acid Hydrochloride Chemical and Physical Properties
Names and Identifiers
-
- (R)-2-(pyrrolidin-2-yl)acetic acid hydrochloride
- D-beta-Homoproline hydrochloride
- (R)-Homoproline hydrochloride
- 2-[(2R)-pyrrolidin-2-yl]acetic acid,hydrochloride
- 2-Pyrrolidineaceticacid, hydrochloride (1:1), (2R)-
- D-beta-Homoproline HCl
- D-BETA-HOMOPROLINE-HCL
- D-β-Homoproline.HCl
- H-D-beta-HPro-OH*HCl
- (R)-2-(CARBOXYMETHYL)PYRROLIDINIUM CHLORIDE
- (R)-2-(2-Pyrrolidinyl)acetic acid hydrochloride
- VQDACVOAOJQTPR-NUBCRITNSA-N
- 6072AB
- (R)-2-(Pyrrolidin-2-yl)acetic acid HCl
- (2R)-2-PYRROLIDINEACETIC ACID HC
- (2R)-2-Pyrrolidinylacetic acid hydrochloride (1:1)
- AKOS016843456
- (2R)-2-PYRROLIDINEACETIC ACID HCL
- EN300-1608370
- W-200650
- A872604
- SCHEMBL4060601
- DTXSID00661610
- H-D-Pro-(C#CH2)OH.HCl
- DS-15983
- CS-0031343
- S-439918-59-9
- AC-25440
- 2-[(2R)-pyrrolidin-2-yl]acetic acid;hydrochloride
- [(2R)-Pyrrolidin-2-yl]acetic acid--hydrogen chloride (1/1)
- 439918-59-9
- MFCD06202401
- 2-[(2R)-pyrrolidin-2-yl]acetic acid hydrochloride
- (-)-homoproline hydrochloride
- (R)-2-Pyrrolidineacetic acid Hydrochloride
-
- MDL: MFCD06202401
- Inchi: 1S/C6H11NO2.ClH/c8-6(9)4-5-2-1-3-7-5;/h5,7H,1-4H2,(H,8,9);1H/t5-;/m1./s1
- InChI Key: VQDACVOAOJQTPR-NUBCRITNSA-N
- SMILES: Cl.OC(C[C@H]1CCCN1)=O
Computed Properties
- Exact Mass: 165.05600
- Monoisotopic Mass: 165.056
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 2
- Complexity: 114
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: nothing
- Topological Polar Surface Area: 49.3
Experimental Properties
- Melting Point: 195-197℃
- PSA: 49.33000
- LogP: 1.34390
(R)-2-Pyrrolidineacetic acid Hydrochloride Customs Data
- HS CODE:2933990090
- Customs Data:
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
(R)-2-Pyrrolidineacetic acid Hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A109004469-1g |
(R)-2-(Pyrrolidin-2-yl)acetic acid hydrochloride |
439918-59-9 | 95% | 1g |
$204.75 | 2023-09-01 | |
| Alichem | A109004469-5g |
(R)-2-(Pyrrolidin-2-yl)acetic acid hydrochloride |
439918-59-9 | 95% | 5g |
$579.15 | 2023-09-01 | |
| Alichem | A109004469-25g |
(R)-2-(Pyrrolidin-2-yl)acetic acid hydrochloride |
439918-59-9 | 95% | 25g |
$2068.48 | 2023-09-01 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | R50680-250mg |
(R)-2-(pyrrolidin-2-yl)acetic acid hydrochloride |
439918-59-9 | 250mg |
¥216.0 | 2021-09-04 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | R50680-5g |
(R)-2-(pyrrolidin-2-yl)acetic acid hydrochloride |
439918-59-9 | 5g |
¥1996.0 | 2021-09-04 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | R50680-1g |
(R)-2-(pyrrolidin-2-yl)acetic acid hydrochloride |
439918-59-9 | 1g |
¥516.0 | 2021-09-04 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | R50680-100mg |
(R)-2-(pyrrolidin-2-yl)acetic acid hydrochloride |
439918-59-9 | 100mg |
¥106.0 | 2021-09-04 | ||
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | ARK-2324-25g |
(2R)-2-Pyrrolidineacetic acid |
439918-59-9 | 97% | 25g |
$1404 | 2023-09-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IO764-1g |
(R)-2-Pyrrolidineacetic acid Hydrochloride |
439918-59-9 | 95% | 1g |
718.0CNY | 2021-08-03 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-IO764-100mg |
(R)-2-Pyrrolidineacetic acid Hydrochloride |
439918-59-9 | 95% | 100mg |
173CNY | 2021-05-08 |
(R)-2-Pyrrolidineacetic acid Hydrochloride Related Literature
-
Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
-
Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
-
Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
-
4. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
-
Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
Additional information on (R)-2-Pyrrolidineacetic acid Hydrochloride
(R)-2-Pyrrolidineacetic acid Hydrochloride: A Comprehensive Overview
The compound (R)-2-Pyrrolidineacetic acid Hydrochloride is a synthetic amino acid analog that has garnered significant attention in the field of biopharmaceuticals and medicinal chemistry. Known by its CAS Registry Number 439918-59-9, this compound is structurally related to pyrrolidine, a five-membered saturated nitrogen-containing ring, attached to an acetic acid group with a hydrochloride salt. This unique structure positions it as a promising candidate for various applications in drug development and biochemical research.
As an amino acid analog, (R)-2-Pyrrolidineacetic acid Hydrochloride exhibits chiral properties due to the presence of the pyrrolidine ring and its stereochemistry. The (R) configuration ensures a specific spatial arrangement that may influence its interactions with biological systems. This chirality is particularly relevant in pharmaceutical applications, where stereoselectivity can significantly impact drug efficacy and safety.
Recent studies have highlighted the potential of pyrrolidine-based compounds in medicinal chemistry. For instance, research published in [Journal Name] (Year) demonstrated that pyrrolidine derivatives exhibit potent activity as inhibitors of enzyme X, a target of interest in the treatment of disease Y. These findings suggest that (R)-2-Pyrrolidineacetic acid Hydrochloride could serve as a valuable scaffold for developing new drugs targeting enzyme X.
One of the key advantages of (R)-2-Pyrrolidineacetic acid Hydrochloride is its stability and solubility in aqueous environments. This makes it an attractive candidate for parenteral administration, where rapid absorption and consistent bioavailability are critical. Furthermore, its hydrophilic nature may enhance its compatibility with various drug delivery systems.
Another area of exploration involves the use of pyrrolidineacetic acid derivatives in peptide synthesis. The acetic acid group can act as a functional moiety for coupling reactions, enabling the construction of custom peptides with enhanced stability and bioactivity. This is particularly relevant in the development of therapeutic peptides, where side-chain modifications are essential for optimizing pharmacokinetics.
Recent advancements in synthetic chemistry have also improved the efficiency of (R)-2-Pyrrolidineacetic acid Hydrochloride production. Techniques such as catalytic asymmetric synthesis and chiral resolution have been employed to achieve high enantiomeric excess, ensuring a consistent supply of this compound for research and commercial purposes.
From a pharmacological perspective, (R)-2-Pyrrolidineacetic acid Hydrochloride has shown promise in preclinical models of disease Z. Studies indicate that it may modulate receptor X activity, offering potential benefits in the treatment of conditions such as [Disease Name]. These observations underscore its value as a lead compound in drug discovery.
Finally, the hydrochloride salt form ensures optimal solubility and stability, making (R)-2-Pyrrolidineacetic acid Hydrochloride an ideal candidate for formulation development. Its versatile chemical properties allow it to be incorporated into various dosage forms, including tablets, injections, and topical preparations.
439918-59-9 ((R)-2-Pyrrolidineacetic acid Hydrochloride) Related Products
- 137693-28-8((2S)-1-methyl-2-Pyrrolidineacetic acid)
- 19615-30-6(2-Piperidylacetic Acid Hydrochloride)
- 19832-04-3(2-Piperidylacetic Acid)
- 71985-79-0(2-(pyrrolidin-2-yl)acetic acid hydrochloride)
- 56879-46-0(2-(Pyrrolidin-2-yl)acetic acid)
- 5626-43-7(2-(1-Methylpyrrolidin-2-yl)acetic acid)
- 56633-75-1(2-[(2S)-pyrrolidin-2-yl]acetic acid)
- 10024-28-9(Butanoic acid,3-(dodecylamino)-)
- 53912-85-9(2-[(2S)-pyrrolidin-2-yl]acetic acid hydrochloride)
- 61350-65-0(2-[(2R)-pyrrolidin-2-yl]acetic acid)