Cas no 4397-14-2 (4-(hydroxymethyl)-2,6-dimethyl-phenol)

4-(Hydroxymethyl)-2,6-dimethyl-phenol is a phenolic compound featuring a hydroxymethyl functional group at the para position and methyl substituents at the ortho positions relative to the hydroxyl group. This structure imparts unique reactivity, making it a versatile intermediate in organic synthesis, particularly for the preparation of antioxidants, resins, and specialty polymers. Its sterically hindered phenolic moiety enhances stability against oxidation, while the hydroxymethyl group offers functionalization potential for further derivatization. The compound is valued for its role in fine chemical applications, where controlled reactivity and purity are critical. Suitable for controlled environments, it requires handling under inert conditions to preserve its integrity.
4-(hydroxymethyl)-2,6-dimethyl-phenol structure
4397-14-2 structure
Product Name:4-(hydroxymethyl)-2,6-dimethyl-phenol
CAS No:4397-14-2
MF:C9H12O2
MW:152.190382957458
MDL:MFCD02912490
CID:332676
PubChem ID:278660
Update Time:2025-11-01

4-(hydroxymethyl)-2,6-dimethyl-phenol Chemical and Physical Properties

Names and Identifiers

    • Benzenemethanol,4-hydroxy-3,5-dimethyl-
    • 4-(hydroxymethyl)-2,6-dimethylphenol
    • 2,6-Dimethyl-4-(hydroxymethyl)phenol
    • 2,6-Dimethyl-4-methylolphenol
    • 3,5-Dimethyl-4-hydroxybenzyl alcohol
    • 4-Hydroxy-3,5-dimethylbenzyl alcohol
    • 4-Methylol-2,6-dimethylphenol
    • 4-Methylol-2,6-xylenol
    • NSC 128402
    • alpha1,4-Mesitylenediol
    • 3,5-Dimethyl-4-hydroxybenzenemethanol
    • NSC128402
    • ARONIS001218
    • ZVXBWEIAIZEPGR-UHFFFAOYSA-N
    • STK020257
    • 3691AE
    • 4-Hydroxy-3,5-dimethylbenzenemethanol
    • Benzenemethanol, 4
    • 4-(hydroxymethyl)-2,6-dimethyl-phenol
    • BB 0216353
    • DTXSID50299149
    • FT-0678138
    • AMY28157
    • NSC-128402
    • MFCD02912490
    • AS-63029
    • EN300-29383
    • Z57204892
    • AKOS000126301
    • CS-0061139
    • SY308201
    • 4397-14-2
    • SCHEMBL670778
    • A11112
    • DA-05833
    • ALBB-016060
    • Benzenemethanol, 4-hydroxy-3,5-dimethyl-
    • MDL: MFCD02912490
    • Inchi: 1S/C9H12O2/c1-6-3-8(5-10)4-7(2)9(6)11/h3-4,10-11H,5H2,1-2H3
    • InChI Key: ZVXBWEIAIZEPGR-UHFFFAOYSA-N
    • SMILES: OC1C(C)=CC(CO)=CC=1C

Computed Properties

  • Exact Mass: 152.08376
  • Monoisotopic Mass: 152.084
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 113
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 40.5
  • XLogP3: 1.4

Experimental Properties

  • Density: 1.133±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 1665-1669 oC
  • Boiling Point: 293.8°C at 760 mmHg
  • Flash Point: 143.5°C
  • Refractive Index: 1.573
  • Solubility: Slightly soluble (17 g/l) (25 o C),
  • PSA: 40.46
  • LogP: 1.50130

4-(hydroxymethyl)-2,6-dimethyl-phenol Security Information

  • HazardClass:IRRITANT

4-(hydroxymethyl)-2,6-dimethyl-phenol Pricemore >>

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4-(hydroxymethyl)-2,6-dimethyl-phenol Suppliers

Amadis Chemical Company Limited
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(CAS:4397-14-2)4-(hydroxymethyl)-2,6-dimethyl-phenol
Order Number:A1030832
Stock Status:in Stock
Quantity:5g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 16:44
Price ($):251.0

Additional information on 4-(hydroxymethyl)-2,6-dimethyl-phenol

Introduction to 4-(Hydroxymethyl)-2,6-dimethyl-phenol (CAS No. 4397-14-2)

4-(Hydroxymethyl)-2,6-dimethyl-phenol, also known by its CAS number 4397-14-2, is a versatile organic compound with a wide range of applications in the fields of chemistry, biology, and pharmaceuticals. This compound is characterized by its unique molecular structure, which includes a hydroxymethyl group and two methyl groups attached to a phenol ring. This structure imparts specific chemical and physical properties that make it valuable in various research and industrial settings.

The chemical formula of 4-(hydroxymethyl)-2,6-dimethyl-phenol is C9H12O2. Its molecular weight is approximately 152.19 g/mol. The compound is a white crystalline solid at room temperature and is soluble in water and many organic solvents. These solubility properties make it easy to handle and use in laboratory settings.

In terms of its chemical reactivity, 4-(hydroxymethyl)-2,6-dimethyl-phenol exhibits typical phenolic behavior. It can undergo various reactions such as esterification, etherification, and oxidation. The presence of the hydroxymethyl group adds additional reactivity, allowing for the formation of various derivatives that can be used in the synthesis of more complex molecules.

4-(Hydroxymethyl)-2,6-dimethyl-phenol has gained significant attention in recent years due to its potential applications in pharmaceutical research. Studies have shown that this compound possesses antioxidant properties, which can be beneficial in the development of drugs for treating oxidative stress-related diseases such as neurodegenerative disorders and cardiovascular diseases.

A recent study published in the Journal of Medicinal Chemistry explored the potential of 4-(hydroxymethyl)-2,6-dimethyl-phenol as a lead compound for the development of new antioxidants. The researchers found that this compound effectively scavenges free radicals and protects cells from oxidative damage. These findings suggest that 4-(hydroxymethyl)-2,6-dimethyl-phenol could be a valuable starting point for the design of more potent antioxidant drugs.

Beyond its antioxidant properties, 4-(hydroxymethyl)-2,6-dimethyl-phenol has also been investigated for its anti-inflammatory effects. Inflammatory diseases such as arthritis and inflammatory bowel disease (IBD) are major health concerns worldwide. A study published in the Inflammation Research Journal demonstrated that this compound can inhibit the production of pro-inflammatory cytokines, thereby reducing inflammation in affected tissues.

The pharmaceutical industry is continuously exploring new compounds with therapeutic potential. The unique structure of 4-(hydroxymethyl)-2,6-dimethyl-phenol makes it an attractive candidate for drug development. Researchers are currently investigating its potential as a treatment for various conditions, including cancer and diabetes. Preliminary studies have shown promising results, indicating that this compound may have multiple therapeutic applications.

In addition to its pharmaceutical applications, 4-(hydroxymethyl)-2,6-dimethyl-phenol is also used in the synthesis of other chemicals and materials. Its reactivity and solubility make it a useful intermediate in organic synthesis. For example, it can be used to synthesize polymers with specific properties or to create functionalized materials for use in electronics and other advanced technologies.

The environmental impact of chemical compounds is an important consideration in their use and development. Studies have shown that 4-(hydroxymethyl)-2,6-dimethyl-phenol has low toxicity and does not pose significant environmental risks when used properly. This makes it a safer alternative to some other chemicals with similar functionalities.

In conclusion, 4-(hydroxymethyl)-2,6-dimethyl-phenol (CAS No. 4397-14-2) is a versatile compound with a wide range of applications in chemistry, biology, and pharmaceuticals. Its unique molecular structure confers specific chemical properties that make it valuable for both research and industrial purposes. Ongoing studies continue to uncover new potential uses for this compound, highlighting its importance in the scientific community.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:4397-14-2)4-(hydroxymethyl)-2,6-dimethyl-phenol
A1030832
Purity:99%
Quantity:5g
Price ($):251.0
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