Cas no 438049-91-3 (tert-butyl (3R,5R)-3,5-dimethylpiperazine-1-carboxylate)

Tert-butyl (3R,5R)-3,5-dimethylpiperazine-1-carboxylate is a chiral piperazine derivative widely used as a key intermediate in pharmaceutical synthesis. Its stereospecific (3R,5R) configuration ensures high enantiopurity, making it valuable for asymmetric synthesis and drug development. The tert-butyloxycarbonyl (Boc) protecting group enhances stability and facilitates selective deprotection under mild acidic conditions. This compound is particularly useful in the preparation of bioactive molecules, including protease inhibitors and other therapeutic agents. Its rigid, dimethyl-substituted piperazine core contributes to conformational control in target structures. The product is typically supplied with high chemical purity, ensuring reproducibility in synthetic applications.
tert-butyl (3R,5R)-3,5-dimethylpiperazine-1-carboxylate structure
438049-91-3 structure
Product Name:tert-butyl (3R,5R)-3,5-dimethylpiperazine-1-carboxylate
CAS No:438049-91-3
MF:C11H22N2O2
MW:214.304583072662
MDL:MFCD08686695
CID:1023871
PubChem ID:51670829
Update Time:2025-10-19

tert-butyl (3R,5R)-3,5-dimethylpiperazine-1-carboxylate Chemical and Physical Properties

Names and Identifiers

    • (3R,5R)-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate
    • (3R,5R)-3,5-Dimethyl-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester
    • TERT-BUTYL (3R,5R)-3,5-DIMETHYLPIPERAZINE-1-CARBOXYLATE
    • AK102255
    • (3R,5R)-1-BOC-3,5-DIMETHYLPIPERAZINE
    • NUZXPHIQZUYMOR-RKDXNWHRSA-N
    • 6039AB
    • FCH2820360
    • AB48028
    • (3R,5R)-1-Boc-3,5-dimethyl-piperazine
    • AX8233794
    • AB0185273
    • (3R,5R)-3,5-Dimethyl-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Es
    • trans-tert-Butyl-3,5-dimethylpiperazine-1-carboxylate
    • (3R,5R)-3,5-Dimethyl-1-piperazinecarb
    • MFCD08686695
    • CS-0048555
    • DS-3797
    • DB-336027
    • SCHEMBL1005767
    • DTXSID30680192
    • P10620
    • 438049-91-3
    • 1-PIPERAZINECARBOXYLIC ACID, 3,5-DIMETHYL-, 1,1-DIMETHYLETHYL ESTER, (3R,5R)-
    • (3R,5R)-tert-Butyl3,5-dimethylpiperazine-1-carboxylate
    • AKOS016004085
    • (3R,5R)-3,5-Dimethyl-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; 1-Piperazinecarboxylic acid, 3,5-dimethyl-, 1,1-dimethylethyl ester, (3R,5R)-; 1,1-Dimethylethyl (3R,5R)-3,5-dimethyl-1-piperazinecarboxylate; (3R,5R)-3,5-Dimethylpiperazine-1-carboxylic acid tert-butyl ester; tert-Butyl (3R,5R)-3,5-dimethylpiperazine-1-c
    • 2216747-02-1
    • tert-butyl (3R,5R)-3,5-dimethylpiperazine-1-carboxylate
    • MDL： MFCD08686695
    • Inchi： 1S/C11H22N2O2/c1-8-6-13(7-9(2)12-8)10(14)15-11(3,4)5/h8-9,12H,6-7H2,1-5H3/t8-,9-/m1/s1
    • InChI Key： NUZXPHIQZUYMOR-RKDXNWHRSA-N
    • SMILES： O(C(C)(C)C)C(N1C[C@@H](C)N[C@H](C)C1)=O

Computed Properties

  • Exact Mass: 214.168127949g/mol
  • Monoisotopic Mass: 214.168127949g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 2
  • Complexity: 225
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 41.6
  • XLogP3: 1.3

Experimental Properties

  • Density: 0.970±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: NA
  • Boiling Point: 279.7±15.0 oC (760 Torr),
  • Flash Point: 123.0±20.4 oC,
  • Solubility: Slightly soluble (8.8 g/l) (25 o C),
  • Vapor Pressure: 0.0±0.6 mmHg at 25°C

tert-butyl (3R,5R)-3,5-dimethylpiperazine-1-carboxylate Security Information

tert-butyl (3R,5R)-3,5-dimethylpiperazine-1-carboxylate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
65R0292-1g
(3R,5R)-1-Boc-3,5-dimethyl-piperazine
 438049-91-3 96%
1g
 5071.29CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
65R0292-5g
(3R,5R)-1-Boc-3,5-dimethyl-piperazine
 438049-91-3 96%
5g
 20268.21CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
65R0292-500mg
(3R,5R)-1-Boc-3,5-dimethyl-piperazine
 438049-91-3 96%
500mg
 2959.67CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
65R0292-250mg
(3R,5R)-1-Boc-3,5-dimethyl-piperazine
 438049-91-3 96%
250mg
 1908.1CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
65R0292-100mg
(3R,5R)-1-Boc-3,5-dimethyl-piperazine
 438049-91-3 96%
100mg
 1382.31CNY 2021-05-07
JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
65R0292-50mg
(3R,5R)-1-Boc-3,5-dimethyl-piperazine
 438049-91-3 96%
50mg
 1110.94CNY 2021-05-07
Alichem
A139001569-250mg
(3R,5R)-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate
 438049-91-3 95%
250mg
 $269.28 2023-09-01
Alichem
A139001569-1g
(3R,5R)-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate
 438049-91-3 95%
1g
 $700.40 2023-09-01
Alichem
A139001569-5g
(3R,5R)-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate
 438049-91-3 95%
5g
 $2801.60 2023-09-01
Fluorochem
227329-250mg
3R,5R)-tert-Butyl 3,5-dimethylpiperazine-1-carboxylate
 438049-91-3 95%
250mg
 ￡216.00 2022-02-28

tert-butyl (3R,5R)-3,5-dimethylpiperazine-1-carboxylate Related Literature

Related Categories

438049-91-3 (tert-butyl (3R,5R)-3,5-dimethylpiperazine-1-carboxylate) Related Products

Recommended suppliers
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
Yunnanjiuzhen
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Yunnanjiuzhen
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.
上海帛亦醫(yī)藥科技有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Suzhou Genelee Bio-Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Suzhou Genelee Bio-Technology Co., Ltd.