Cas no 435341-92-7 (1-Ethyl-4-piperidin-4-yl-piperazine)

1-Ethyl-4-piperidin-4-yl-piperazine is a versatile heterocyclic compound featuring both piperazine and piperidine moieties, offering a unique structural framework for pharmaceutical and chemical applications. Its bifunctional design enables it to serve as a valuable intermediate in the synthesis of bioactive molecules, particularly in the development of CNS-targeting drugs and receptor modulators. The compound's ethyl substitution enhances lipophilicity, potentially improving membrane permeability in drug candidates. Its rigid yet flexible structure allows for precise spatial orientation in molecular interactions, making it useful for medicinal chemistry optimization. The secondary amine groups provide reactive sites for further derivatization, facilitating the creation of diverse chemical libraries for research and development purposes.
1-Ethyl-4-piperidin-4-yl-piperazine structure
435341-92-7 structure
Product Name:1-Ethyl-4-piperidin-4-yl-piperazine
CAS No:435341-92-7
MF:C11H23N3
MW:197.320422410965
CID:928991
PubChem ID:535780
Update Time:2025-06-08

1-Ethyl-4-piperidin-4-yl-piperazine Chemical and Physical Properties

Names and Identifiers

    • 1-Ethyl-4-(piperidin-4-yl)piperazine
    • 1-ETHYL-4-PIPERIDIN-4-YL-PIPERAZINE
    • 1-ethyl-4-(piperidin-4-yl)piperazine hydrochloride
    • 1-ethyl-4-piperidin-4-yl-piperazine hydrochloride
    • CHEMBRDG-BB 4100005
    • TIMTEC-BB SBB010967
    • SCHEMBL1479533
    • DB-066118
    • CHEMBL4566983
    • 1-Ethyl-4-(4-piperidinyl)piperazine
    • Piperazine, 1-ethyl-4-(4-piperidinyl)-
    • CIA99177
    • 202991-77-3
    • 1-Ethyl-4-(4-piperidinyl)piperazine #
    • BAS 04918779
    • 1-ethyl-4-piperidin-4-ylpiperazine
    • DTXSID401292864
    • CS-0298532
    • EN300-58269
    • AB00997141-01
    • 1-ethyl-4-piperidin-4-yl-piperazine, AldrichCPR
    • DB-363641
    • Piperazine, 1-ethyl-4-(4-piperidyl)-
    • MFCD03446414
    • AKOS000175139
    • 435341-92-7
    • OTAVA-BB 1194537
    • BS-35806
    • l-ethyl-4-(piperidin-4-yl)piperazine hydrochloride
    • SCHEMBL15352805
    • Y11602
    • 1-Ethyl-4-piperidin-4-yl-piperazinehydrochloride
    • BS-49454
    • 1-Ethyl-4-(4-piperidyl)piperazine Hydrochloride
    • IXHUOPCJAWPKNT-UHFFFAOYSA-N
    • 1-Ethyl-4-(piperidin-4-yl)piperazine HCl
    • MFCD06800708
    • 1-ethyl-4-(piperidin-4-yl)piperazinehydrochloride
    • CS-0163026
    • A1-00415
    • SY317226
    • AKOS015846838
    • 1-Ethyl-4-piperidin-4-yl-piperazine
    • MDL： MFCD06800708
    • Inchi： 1S/C11H23N3/c1-2-13-7-9-14(10-8-13)11-3-5-12-6-4-11/h11-12H,2-10H2,1H3
    • InChI Key： JOXMSOKQNJLNEN-UHFFFAOYSA-N
    • SMILES： N1(CCN(CC)CC1)C1CCNCC1

Computed Properties

  • Exact Mass: 197.18900
  • Monoisotopic Mass: 197.189197746g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 2
  • Complexity: 158
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.6
  • Topological Polar Surface Area: 18.5?2

Experimental Properties

  • PSA: 18.51000
  • LogP: 0.58050

1-Ethyl-4-piperidin-4-yl-piperazine Customs Data

  • HS CODE：2933599090
  • Customs Data：

    China Customs Code:

    2933599090

    Overview:

    2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-Ethyl-4-piperidin-4-yl-piperazine Pricemore >>

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1-Ethyl-4-piperidin-4-yl-piperazine Related Literature

Related Categories

Additional information on 1-Ethyl-4-piperidin-4-yl-piperazine

Recent Advances in the Study of 1-Ethyl-4-piperidin-4-yl-piperazine (CAS: 435341-92-7) in Chemical Biology and Pharmaceutical Research

1-Ethyl-4-piperidin-4-yl-piperazine (CAS: 435341-92-7) is a piperazine derivative that has garnered significant attention in recent years due to its potential applications in chemical biology and pharmaceutical research. This compound, characterized by its unique structural features, has been explored for its role in modulating various biological targets, including receptors and enzymes. Recent studies have focused on its synthesis, pharmacological properties, and potential therapeutic applications, making it a subject of interest for researchers in the field.

One of the key areas of investigation has been the compound's interaction with central nervous system (CNS) targets. Preliminary studies suggest that 1-Ethyl-4-piperidin-4-yl-piperazine exhibits affinity for serotonin and dopamine receptors, which could have implications for the treatment of neurological and psychiatric disorders. Researchers have employed advanced techniques such as molecular docking and in vitro binding assays to elucidate its mechanism of action, providing a foundation for further drug development efforts.

In addition to its CNS-related applications, recent research has explored the compound's potential as a scaffold for the design of novel chemotherapeutic agents. Structural modifications of 1-Ethyl-4-piperidin-4-yl-piperazine have yielded derivatives with promising anti-proliferative activity against various cancer cell lines. These findings highlight the versatility of this compound and its potential to serve as a lead structure in oncology drug discovery.

The synthesis and optimization of 1-Ethyl-4-piperidin-4-yl-piperazine have also been a focus of recent studies. Researchers have developed efficient synthetic routes to produce the compound with high purity and yield, addressing previous challenges in its preparation. These advancements are critical for enabling large-scale production and further pharmacological evaluation.

Despite the progress made, several challenges remain. The pharmacokinetic properties of 1-Ethyl-4-piperidin-4-yl-piperazine, such as its bioavailability and metabolic stability, require further investigation. Additionally, more in vivo studies are needed to validate its therapeutic potential and assess any potential side effects. Future research directions may include the development of prodrugs or formulation strategies to enhance its delivery and efficacy.

In conclusion, 1-Ethyl-4-piperidin-4-yl-piperazine (CAS: 435341-92-7) represents a promising compound with diverse applications in chemical biology and pharmaceutical research. Its unique structural and pharmacological properties make it a valuable tool for drug discovery and development. Continued research efforts will be essential to fully unlock its potential and translate these findings into clinical applications.

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