• 1. An atlas of endohedral Sc2S cluster fullerenes?
  Li-Hua Gan,Rui Wu,Jian-Lei Tian,Patrick W. Fowler Phys. Chem. Chem. Phys., 2017,19, 419-425
• 2. An approach towards the synthesis of novel fused nitrogen tricyclic heterocyclic scaffolds via GBB reaction?
  Sandip Gangadhar Balwe,Yeon Tae Jeong Org. Biomol. Chem., 2018,16, 1287-1296
• 3. Acenaphthenic hopanoids, a novel series of aromatised
  Teresita Carrillo-Hernández,Philippe Schaeffer,Pierre Albrecht Chem. Commun., 2001, 1976-1977
• 4. An artificial CO-releasing metalloprotein built by histidine-selective metallation?
  Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
• 5. An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment?
  Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099

• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Stilbenes Stilbenes
• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Stilbenes

4-(E)-2-phenylethenylaniline (CAS No. 4309-66-4): A Comprehensive Overview

4-(E)-2-phenylethenylaniline, also known by its CAS registry number 4309-66-4, is a compound of significant interest in both academic and industrial research. This compound belongs to the class of aromatic amines and is characterized by its unique structure, which includes a phenyl group attached to an ethenyl chain, further linked to an aniline moiety. The E configuration of the double bond in the ethenyl group imparts specific electronic and steric properties, making it a versatile molecule for various applications.

Recent advancements in synthetic chemistry have enabled the efficient synthesis of 4-(E)-2-phenylethenylaniline through methods such as Stille coupling and Suzuki-Miyaura coupling. These methods not only enhance the purity of the compound but also allow for the exploration of its structural analogs, which are crucial for understanding its reactivity and functionality. The compound has been extensively studied for its potential in pharmaceuticals, agrochemicals, and advanced materials.

In the field of materials science, 4-(E)-2-phenylethenylaniline has been utilized as a precursor for synthesizing novel polymers and organic semiconductors. Its ability to form stable π-conjugated systems makes it an ideal candidate for applications in organic electronics, such as field-effect transistors (FETs) and light-emitting diodes (LEDs). Recent studies have demonstrated that incorporating this compound into polymer backbones can significantly improve charge transport properties, paving the way for next-generation electronic devices.

The pharmacological potential of 4-(E)-2-phenylethenylaniline has also garnered attention. Preclinical studies have shown that this compound exhibits antioxidant properties and may play a role in mitigating oxidative stress-related diseases. Additionally, its ability to modulate enzyme activity suggests potential applications in drug discovery, particularly in the development of agents targeting neurodegenerative disorders such as Alzheimer's disease.

From an environmental perspective, researchers have investigated the biodegradation pathways of 4-(E)-2-phenylethenylaniline to assess its ecological impact. Studies indicate that under aerobic conditions, the compound undergoes rapid microbial degradation, reducing concerns about its persistence in natural ecosystems. This information is critical for industries aiming to adopt sustainable practices and minimize environmental footprints.

In conclusion, 4-(E)-2-phenylethenylaniline (CAS No. 4309-66-4) stands out as a multifaceted compound with diverse applications across various scientific domains. Its unique chemical properties, coupled with advancements in synthetic methodologies and application-oriented research, position it as a key player in future technological innovations. As ongoing studies continue to unravel its full potential, this compound is poised to make significant contributions to both scientific research and industrial development.

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