Cas no 424792-57-4 (1,2-difluoro-4-methanesulfonylbenzene)
1,2-Difluoro-4-methanesulfonylbenzene is a fluorinated aromatic compound featuring a methanesulfonyl substituent at the para position relative to the difluorinated benzene ring. This structure imparts unique electronic and steric properties, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The electron-withdrawing sulfonyl group enhances reactivity in nucleophilic substitution reactions, while the fluorine atoms contribute to metabolic stability and bioavailability in active ingredients. Its high purity and well-defined chemical characteristics ensure consistent performance in cross-coupling reactions and other transformations. The compound is particularly useful in the development of sulfonamide-based therapeutics and specialty chemicals, offering precise control over molecular design.
424792-57-4 structure
Product Name:1,2-difluoro-4-methanesulfonylbenzene
CAS No:424792-57-4
MF:C7H6F2O2S
MW:192.183147907257
MDL:MFCD04037934
CID:68065
PubChem ID:253661751
Update Time:2025-05-28
1,2-difluoro-4-methanesulfonylbenzene Chemical and Physical Properties
Names and Identifiers
-
- 1,2-Difluoro-4-(methylsulfonyl)benzene
- 1,2-difluoro-4-methylsulfonylbenzene
- 3,4-Difluorophenyl Methyl Sulfone
- 1,2-DIFLUORO-4-(METHYLSULPHONYL)BENZENE
- 1,2-difluoro-4-methanesulfonylbenzene
- 1,2-Difluoro-4-methanesulfonyl-benzene
- 1,2-difluoro-4-methylsulfonyl-benzene
- PubChem20706
- WMBJGJXMKCOHGG-UHFFFAOYSA-N
- STL555517
- SBB091409
- BBL101720
- TRA0037450
- AS0
- AS05707
-
- MDL： MFCD04037934
- Inchi： 1S/C7H6F2O2S/c1-12(10,11)5-2-3-6(8)7(9)4-5/h2-4H,1H3
- InChI Key： WMBJGJXMKCOHGG-UHFFFAOYSA-N
- SMILES： S(C)(C1C=CC(=C(C=1)F)F)(=O)=O
Computed Properties
- Exact Mass: 192.00600
- Monoisotopic Mass: 192.006
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 12
- Rotatable Bond Count: 1
- Complexity: 245
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.5
- Topological Polar Surface Area: 42.5
- Surface Charge: 0
- Tautomer Count: nothing
Experimental Properties
- Density: 1.376
- Melting Point: 75.0 to 79.0 deg-C
- Boiling Point: 302.4°C at 760 mmHg
- Flash Point: 136.7℃
- Refractive Index: 1.49
- PSA: 42.52000
- LogP: 2.44910
1,2-difluoro-4-methanesulfonylbenzene Security Information
- Signal Word：Warning
- Hazard Statement： H302-H315-H319-H335
- Warning Statement： P261-P305+P351+P338
- Safety Instruction： S26; S36/37/39
-
Hazardous Material Identification：
- Storage Condition：Sealed in dry,Room Temperature
- Risk Phrases：R36/37/38
1,2-difluoro-4-methanesulfonylbenzene Customs Data
- HS CODE：2904909090
- Customs Data：
China Customs Code:
2904909090Overview:
2904909090 Sulfonation of other hydrocarbons\nitrification\Nitrosative derivative(Whether halogenated or not). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
1,2-difluoro-4-methanesulfonylbenzene Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 023629-1g |
1,2-Difluoro-4-(methylsulfonyl)benzene |
424792-57-4 | 97% | 1g |
￡16.00 | 2022-03-01 | |
| Fluorochem | 023629-5g |
1,2-Difluoro-4-(methylsulfonyl)benzene |
424792-57-4 | 97% | 5g |
￡40.00 | 2022-03-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D135909-1g |
1,2-difluoro-4-methanesulfonylbenzene |
424792-57-4 | 98% | 1g |
￥143.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D135909-250mg |
1,2-difluoro-4-methanesulfonylbenzene |
424792-57-4 | 98% | 250mg |
￥83.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | D135909-5g |
1,2-difluoro-4-methanesulfonylbenzene |
424792-57-4 | 98% | 5g |
￥648.90 | 2023-09-03 | |
| Alichem | A019088255-25g |
1,2-Difluoro-4-(methylsulfonyl)benzene |
424792-57-4 | 95% | 25g |
$254.40 | 2023-09-01 | |
| Alichem | A019088255-100g |
1,2-Difluoro-4-(methylsulfonyl)benzene |
424792-57-4 | 95% | 100g |
$675.18 | 2023-09-01 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R020492-1g |
1,2-difluoro-4-methanesulfonylbenzene |
424792-57-4 | 95% | 1g |
￥62 | 2024-05-23 | |
| TRC | D448633-100mg |
1,2-Difluoro-4-methylsulfonylbenzene |
424792-57-4 | 100mg |
$64.00 | 2023-05-18 | ||
| TRC | D448633-250mg |
1,2-Difluoro-4-methylsulfonylbenzene |
424792-57-4 | 250mg |
$75.00 | 2023-05-18 |
1,2-difluoro-4-methanesulfonylbenzene Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:424792-57-4)1,2-difluoro-4-methanesulfonylbenzene
Order Number:A856637
Stock Status:in Stock
Quantity:100g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 08:01
Price ($):417.0
Email:[email protected]
1,2-difluoro-4-methanesulfonylbenzene Related Literature
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Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
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Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
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Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090
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Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
424792-57-4 (1,2-difluoro-4-methanesulfonylbenzene) Related Products
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- 845616-49-1(1,2,4-Trifluoro-5-(methylsulfonyl)benzene)
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Recommended suppliers
Amadis Chemical Company Limited
(CAS:424792-57-4)1,2-difluoro-4-methanesulfonylbenzene
Purity:99%
Quantity:100g
Price ($):417.0