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• Solvents and Organic Chemicals Organic Compounds Nucleosides, nucleotides, and analogues Purine nucleotides Purine ribonucleoside triphosphates
• Solvents and Organic Chemicals Organic Compounds Nucleosides, nucleotides, and analogues Purine nucleotides Purine ribonucleotides Purine ribonucleoside triphosphates

Adenosine 5'-Triphosphate Potassium Salt (CAS No. 42373-41-1): A Comprehensive Overview

Adenosine 5'-triphosphate potassium salt, commonly referred to as ATP potassium salt, is a crucial molecule in biochemistry and molecular biology. With the CAS number 42373-41-1, this compound plays a pivotal role in energy transfer within cells and serves as a key component in various biological processes. The molecule consists of adenosine attached to three phosphate groups, forming a high-energy phosphate bond that is essential for cellular energy currency. The potassium salt form of ATP is particularly significant due to its stability and bioavailability, making it widely used in research and industrial applications.

The structure of adenosine 5'-triphosphate potassium salt comprises an adenosine moiety, which includes an adenine base linked to a ribose sugar, and three phosphate groups connected via high-energy bonds. These bonds store energy that is released during the hydrolysis of ATP to adenosine diphosphate (ADP) or adenosine monophosphate (AMP). This energy release is fundamental for driving numerous cellular processes, including muscle contraction, nerve impulse propagation, and biosynthetic reactions. Recent studies have highlighted the role of ATP in extracellular signaling, where it acts as a neurotransmitter and regulates immune responses, further underscoring its versatility.

In terms of applications, ATP potassium salt is extensively utilized in biochemical research. It serves as an essential reagent in enzyme assays, protein synthesis reactions, and cell culture media. Researchers have recently explored its role in mitochondrial function and energy metabolism, particularly in the context of aging and neurodegenerative diseases. Additionally, ATP has been implicated in the regulation of intracellular calcium levels through its interaction with ATP-sensitive potassium channels, a finding that has significant implications for cardiovascular research.

The production of adenosine 5'-triphosphate potassium salt involves complex chemical synthesis processes or extraction from natural sources such as bacterial cultures. Modern advancements have led to the development of more efficient synthesis methods, ensuring higher purity and scalability for industrial use. Quality control measures are critical to ensure the product meets stringent standards for biological applications.

In the field of biotechnology, ATP potassium salt is integral to processes like PCR (polymerase chain reaction) and DNA sequencing. Recent innovations have optimized its use in these applications, enhancing reaction efficiency and accuracy. Moreover, ATP has been explored as a potential therapeutic agent in treating conditions like ischemia-reperfusion injury due to its role in modulating cellular energetics.

The study of ATP's interactions with proteins and nucleic acids has also advanced significantly. Structural biology techniques such as X-ray crystallography and cryo-electron microscopy have provided insights into how ATP binds to its target molecules, aiding drug discovery efforts targeting ATP-dependent enzymes.

In conclusion, adenosine 5'-triphosphate potassium salt remains a cornerstone molecule in biochemistry with diverse applications across research and industry. Its role in cellular energetics and signaling continues to be a focal point for scientific investigation, driven by advancements in molecular biology techniques and computational modeling.

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• 102783-40-4(Adenosine5'-(tetrahydrogen triphosphate), P''®5'-ester with adenosine, triammonium salt (9CI))