Cas no 41941-56-4 (8-Chloroadenosine 3',5'-Cyclic Monophosphate)
8-Chloroadenosine 3',5'-Cyclic Monophosphate Chemical and Physical Properties
Names and Identifiers
-
- Adenosine, 8-chloro-,cyclic 3',5'-(hydrogen phosphate)
- 8-CHLOROADENOSINE-CYCLIC -3',5'-MONOPHOSPHATE
- 8-CHLORO-CAMP
- 8-chloroadenosine 3',5'-cyclic-monophosphate
- 8-chloroadenosine 3',5'-monophosphate
- 8-chloro-cyclicadenosinemonophosphate
- 8-chlorocyclicamp
- 8-chloro-O3',O5'-hydroxyphosphoryl-adenosine
- 8-CL-CAMP
- Tocladesine
- 8-Chloroadenosine 3′,5′-monophosphate
- TOCLADESINE [USAN]
- BQ94Z7E5OR
- 8-Chloro-cyclic adenosine monophosphate
- Adenosine, 8-chloro-, cyclic 3',5'-(hydrogen phosphate)
- 8-chloro-cyclic AMP
- CN1256
- W-202723
- Tocladesine (USAN/INN)
- Q27274811
- ADENAZOLE
- CHEMBL2107085
- SCHEMBL125595
- NSC614491
- NSC-614491
- DTXSID101024678
- CN 1256
- DB13046
- (4AR,6R,7R,7AS)-6-(6-AMINO-8-CHLORO-PURIN-9-YL)-2-OXO-TETRAHYDRO-2LAMBDA*5*-FURO(3,2-D)(1,3,2)DIOXAPHOSPHININE-2,7-DIOL
- 6-(6-amino-8-chloropurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
- CCRIS 846
- NSC-284751
- 41941-56-4
- UNII-BQ94Z7E5OR
- NSC 614491
- HY-123396
- 8-Chloroadenosine-cyclic-3',5'-monophosphate dihydrate
- 8-chloroadenosine 3',5'-cyclic monophosphate
- 8-Chloroadenosine-3',5'-O-monophosphate
- 8-CHLOROADENOSINE-cyclic-3',5'-MONOPHOSPHATE
- MFCD00153938
- TOCLADESINE [INN]
- NS00069841
- Tocladesine [USAN:INN:BAN]
- D06173
- NCS 614491
- ICN-1256
- (4aR,6R,7R,7aS)-6-(6-amino-8-chloropurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
- 8-CHLORO-CYCLIC ADENOSINE 3',5'-MONOPHOSPHATE
- (4aR,6R,7R,7aS)-6-(6-amino-8-chloro-purin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
- AKOS040749661
- 8-Chloroadenosine 3',5'-cyclic phosphate
- 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-8-chloro-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, (4aR,6R,7R,7aS)-
- 8-CHLORO CYCLIC AMP
- DA-70375
- CLLFEJLEDNXZNR-UUOKFMHZSA-N
- 8-Chloroadenosine 3',5'-Cyclic Monophosphate
-
- MDL： MFCD00153938
- Inchi： 1S/C10H11ClN5O6P/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14)/t3-,5-,6-,9-/m1/s1
- InChI Key： CLLFEJLEDNXZNR-UUOKFMHZSA-N
- SMILES： ClC1=NC2C(N)=NC=NC=2N1[C@H]1[C@@H]([C@H]2[C@@H](COP(=O)(O)O2)O1)O
Computed Properties
- Exact Mass: 363.01400
- Monoisotopic Mass: 363.0135478g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 10
- Heavy Atom Count: 23
- Rotatable Bond Count: 1
- Complexity: 532
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 4
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 3
- XLogP3: -1.6
- Topological Polar Surface Area: 155
Experimental Properties
- Color/Form: Not determined
- Density: 2.6±0.1 g/cm3
- Boiling Point: 731.7±70.0 °C at 760 mmHg
- Flash Point: 396.3±35.7 °C
- Solubility: aqueous base: soluble
- PSA: 164.65000
- LogP: 0.41720
- Solubility: Soluble
- Vapor Pressure: 0.0±2.5 mmHg at 25°C
8-Chloroadenosine 3',5'-Cyclic Monophosphate Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Safety Instruction： H303+H313+H333
- RTECS：AU7357552
- Storage Condition：?20°C
8-Chloroadenosine 3',5'-Cyclic Monophosphate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | C364103-1mg |
8-Chloroadenosine 3',5'-Cyclic Monophosphate |
41941-56-4 | 1mg |
$ 64.00 | 2023-04-18 | ||
| TRC | C364103-2.5mg |
8-Chloroadenosine 3',5'-Cyclic Monophosphate |
41941-56-4 | 2.5mg |
$ 115.00 | 2023-04-18 | ||
| 1PlusChem | 1P00C00J-1mg |
8-CHLORO-CAMP |
41941-56-4 | 99% | 1mg |
$723.00 | 2024-05-02 | |
| 1PlusChem | 1P00C00J-5mg |
8-CHLORO-CAMP |
41941-56-4 | 99% | 5mg |
$1616.00 | 2024-05-02 | |
| A2B Chem LLC | AF59091-1mg |
8-CHLORO-CAMP |
41941-56-4 | 99% | 1mg |
$635.00 | 2024-04-20 | |
| A2B Chem LLC | AF59091-5mg |
8-CHLORO-CAMP |
41941-56-4 | 99% | 5mg |
$1415.00 | 2024-04-20 | |
| Ambeed | A588161-1mg |
8-Chloro-cAMP |
41941-56-4 | 98% | 1mg |
$842.0 | 2024-07-19 | |
| Ambeed | A588161-5mg |
8-Chloro-cAMP |
41941-56-4 | 95% | 5mg |
$2299.0 | 2025-04-19 | |
| MedChemExpress | HY-123396-1mg |
8-Chloro-cAMP |
41941-56-4 | ≥99.0% | 1mg |
￥3960 | 2025-04-16 |
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8-Chloroadenosine 3',5'-Cyclic Monophosphate Related Literature
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Jason Wan Lab Chip, 2020,20, 4528-4538
-
Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
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Yiding Jiao,Liqun Kang,Jasper Berry-Gair,Kit McColl,Jianwei Li,Haobo Dong,Hao Jiang,Ryan Wang,Furio Corà,Dan J. L. Brett,Ivan P. Parkin J. Mater. Chem. A, 2020,8, 22075-22082
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Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
Related Categories
- Solvents and Organic Chemicals Organic Compounds Nucleosides, nucleotides, and analogues Purine nucleotides 3',5'-cyclic purine nucleotides
- Solvents and Organic Chemicals Organic Compounds Nucleosides, nucleotides, and analogues Purine nucleotides Cyclic purine nucleotides 3',5'-cyclic purine nucleotides
Additional information on 8-Chloroadenosine 3',5'-Cyclic Monophosphate
8-Chloroadenosine 3',5'-Cyclic Monophosphate: A Comprehensive Overview
8-Chloroadenosine 3',5'-Cyclic Monophosphate, also known by its CAS number 41941-56-4, is a bioactive compound that has garnered significant attention in the fields of pharmacology and molecular biology. This compound is a derivative of adenosine monophosphate (AMP), with a chlorine substituent at the 8-position of the purine ring. Its unique structure endows it with distinct pharmacological properties, making it a valuable tool in research and potential therapeutic applications.
The synthesis of 8-Chloroadenosine 3',5'-Cyclic Monophosphate involves several steps, including the modification of adenosine to incorporate the chlorine atom at the 8-position. This substitution is crucial as it alters the compound's physicochemical properties, enhancing its stability and bioavailability. Recent studies have explored novel synthetic methodologies to improve the yield and purity of this compound, ensuring its reliability for experimental use.
One of the most notable applications of 8-Chloroadenosine 3',5'-Cyclic Monophosphate is in the study of cellular signaling pathways. This compound acts as an analog of cyclic AMP (cAMP), a key second messenger molecule involved in various cellular processes, including gene expression, metabolism, and cell proliferation. By mimicking cAMP, 8-Chloroadenosine 3',5'-Cyclic Monophosphate can modulate protein kinase A (PKA) activity, providing researchers with a powerful tool to investigate signaling cascades in vitro and in vivo.
Recent advancements in research have highlighted the potential therapeutic benefits of 8-Chloroadenosine 3',5'-Cyclic Monophosphate. For instance, studies have demonstrated its ability to inhibit certain enzymes associated with inflammatory responses, suggesting its potential use in anti-inflammatory therapies. Additionally, preclinical trials have shown promising results in models of neurodegenerative diseases, where this compound exhibits neuroprotective effects by modulating cAMP-dependent pathways.
The pharmacokinetics and toxicity profile of 8-Chloroadenosine 3',5'-Cyclic Monophosphate have also been extensively studied. Research indicates that this compound has a favorable safety profile, with minimal adverse effects observed at therapeutic concentrations. However, further studies are required to fully understand its long-term effects and mechanisms of action in complex biological systems.
In conclusion, 8-Chloroadenosine 3',5'-Cyclic Monophosphate, CAS No. 41941-56-4, represents a significant advancement in the field of bioactive compounds. Its unique properties and versatile applications make it an invaluable tool for researchers and clinicians alike. As ongoing studies continue to uncover new insights into its mechanisms and therapeutic potential, this compound is poised to play a pivotal role in the development of innovative treatments for various diseases.
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