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• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Sulfonylureas
• Solvents and Organic Chemicals Organic Compounds Heterocyclic Compounds

Comprehensive Overview of 3-Methanesulfonyl-2-oxo-1-imidazolidinecarbonyl Chloride (CAS No. 41762-76-9)

3-Methanesulfonyl-2-oxo-1-imidazolidinecarbonyl Chloride (CAS 41762-76-9) is a highly specialized chemical compound widely utilized in pharmaceutical and agrochemical research. Its unique molecular structure, featuring a methanesulfonyl group and a reactive carbonyl chloride moiety, makes it a valuable intermediate in the synthesis of bioactive molecules. Researchers often search for "imidazolidine derivatives" or "sulfonyl chloride applications" to understand its role in modern drug discovery.

The growing interest in heterocyclic compounds like 3-Methanesulfonyl-2-oxo-1-imidazolidinecarbonyl Chloride stems from their versatility in medicinal chemistry. Recent trends show increased searches for "small molecule drug development" and "targeted protein degradation," where this compound's imidazolidine core demonstrates potential. Its carbonyl chloride functionality enables efficient conjugation with amines or alcohols, a feature frequently explored in "click chemistry" and "bioconjugation techniques.

In analytical chemistry, CAS 41762-76-9 has gained attention for its chromatographic behavior, with many researchers investigating "HPLC method development" for similar sulfonamide-containing compounds. The compound's methanesulfonyl group contributes to its polarity, influencing retention times in reverse-phase systems—a hot topic in "analytical method optimization" discussions.

Environmental scientists examining "green chemistry alternatives" have noted the compound's potential in sustainable synthesis routes. While not classified as hazardous, proper handling of 3-Methanesulfonyl-2-oxo-1-imidazolidinecarbonyl Chloride aligns with industry-wide "laboratory safety best practices." Its stability under various conditions makes it suitable for "high-throughput screening" applications, a frequently searched term in combinatorial chemistry.

The pharmaceutical industry's shift toward "fragment-based drug design" has increased demand for building blocks like imidazolidine derivatives. Patent analyses reveal growing applications of CAS 41762-76-9 in "kinase inhibitor development" and "allosteric modulator synthesis." These applications correlate with trending searches for "cancer therapeutics" and "precision medicine approaches.

Quality control specialists often search for "spectroscopic characterization methods" when working with 3-Methanesulfonyl-2-oxo-1-imidazolidinecarbonyl Chloride. The compound's distinct 1H-NMR signatures (particularly the methanesulfonyl protons at ~3.5 ppm) and carbonyl stretching vibrations (~1750 cm^-1 in IR) provide reliable identification markers, important for "chemical purity verification protocols.

Emerging research in "computational chemistry" utilizes 41762-76-9 as a model compound for studying molecular orbital interactions in five-membered heterocycles. This connects with popular queries about "DFT calculations" and "molecular docking simulations." The compound's balanced lipophilicity (logP ~1.2) also makes it relevant to "ADMET prediction" studies.

Supply chain professionals tracking "specialty chemical availability" should note that 3-Methanesulfonyl-2-oxo-1-imidazolidinecarbonyl Chloride typically ships as a crystalline solid with extended shelf stability. Storage recommendations (2-8°C under inert atmosphere) align with standard "chemical inventory management" practices for sensitive carbonyl compounds.

Academic laboratories investigating "mechanistic organic chemistry" value this compound for studying nucleophilic acyl substitution reactions. The imidazolidine ring strain influences reaction kinetics—a subject frequently searched alongside "reaction rate optimization." These fundamental studies support broader applications in "catalysis research and "asymmetric synthesis."

Recent advancements in "continuous flow chemistry" have explored the use of CAS 41762-76-9 in microreactor systems, addressing common search terms like "process intensification" and "scale-up challenges." The compound's moderate solubility in aprotic solvents enables efficient handling in these modern synthetic platforms.

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