Cas no 41743-86-6 ((3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-o)
(3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-o Chemical and Physical Properties
Names and Identifiers
-
- 2H-1-Benzopyran-7-ol,3-(2,4-dimethoxyphenyl)-3,4-dihydro-, (3R)-
- (-)-Sativan
- (3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-ol
- SATIVAN
- 2-hydroxy-2',4'-dimethoxyisoflavan
- LMPK12080025
- C10526
- Q27105244
- (3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol
- 2H-1-Benzopyran-7-ol, 3-(2,4-dimethoxyphenyl)-3,4-dihydro-, (3R)-
- 41743-86-6
- Sativin (alfalfa)
- Sativan, (R)-
- DTXSID80194577
- AKOS040762684
- (R)-Sativan
- Sativin
- NAZ6L3EV54
- CHEBI:115
- (R)-3-(2,4-dimethoxyphenyl)chroman-7-ol
- AKOS040762304
- 3-(2,4-Dimethoxyphenyl)-7-chromanol #
- 2H-1-Benzopyran-7-ol, 3-(2,4-dimethoxyphenyl)-3,4-dihydro-
- 2'-O-Methylvestitol
- 7-hydroxy-2',4'-dimethoxyisoflavan
- 3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-ol
- TUXCLJQCYVCGDW-UHFFFAOYSA-N
- 71831-00-0
- DTXCID20117068
- (3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-o
-
- Inchi： 1S/C17H18O4/c1-19-14-5-6-15(17(9-14)20-2)12-7-11-3-4-13(18)8-16(11)21-10-12/h3-6,8-9,12,18H,7,10H2,1-2H3/t12-/m0/s1
- InChI Key： TUXCLJQCYVCGDW-LBPRGKRZSA-N
- SMILES： O1C2C([H])=C(C([H])=C([H])C=2C([H])([H])[C@]([H])(C2C([H])=C([H])C(=C([H])C=2OC([H])([H])[H])OC([H])([H])[H])C1([H])[H])O[H]
Computed Properties
- Exact Mass: 286.12050905g/mol
- Monoisotopic Mass: 286.12050905g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 21
- Rotatable Bond Count: 3
- Complexity: 335
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 47.9
- XLogP3: 3.3
Experimental Properties
- Color/Form: Powder
- Density: 1.2±0.1 g/cm3
- Boiling Point: 443.6±45.0 °C at 760 mmHg
- Flash Point: 222.1±28.7 °C
- Refractive Index: 1.584
- Vapor Pressure: 0.0±1.1 mmHg at 25°C
(3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-o Security Information
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：Store at 4 ℃, better at -4 ℃
(3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-o Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | S43200-5 mg |
2H-1-Benzopyran-7-ol,3-(2,4-dimethoxyphenyl)-3,4-dihydro-, (3R)- |
41743-86-6 | 5mg |
￥4640.0 | 2021-09-07 | ||
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN5480-5 mg |
(-)-Sativan |
41743-86-6 | 5mg |
￥4465.00 | 2022-04-26 | ||
| TargetMol Chemicals | TN5480-5 mg |
(-)-Sativan |
41743-86-6 | 98% | 5mg |
￥ 3,230 | 2023-07-11 | |
| TargetMol Chemicals | TN5480-1 mL * 10 mM (in DMSO) |
(-)-Sativan |
41743-86-6 | 98% | 1 mL * 10 mM (in DMSO) |
￥ 3330 | 2023-09-15 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN5480-5mg |
(-)-Sativan |
41743-86-6 | 5mg |
￥ 3230 | 2023-09-08 | ||
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN5480-1 mL * 10 mM (in DMSO) |
(-)-Sativan |
41743-86-6 | 1 mL * 10 mM (in DMSO) |
￥ 3330 | 2023-09-08 | ||
| TargetMol Chemicals | TN5480-5mg |
(-)-Sativan |
41743-86-6 | 5mg |
￥ 3230 | 2024-07-20 | ||
| TargetMol Chemicals | TN5480-1 ml * 10 mm |
(-)-Sativan |
41743-86-6 | 1 ml * 10 mm |
￥ 3330 | 2024-07-20 |
(3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-o Related Literature
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1. Biosynthesis of isoflavonoid phytoalexins in Medicago sativa: the biosynthetic relationship between pterocarpans and 2′-hydroxyisoflavansPaul M. Dewick,Maria Martin J. Chem. Soc. Chem. Commun. 1976 637
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Azra Gholami,Nathan De Geyter,Jacob Pollier,Sofie Goormachtig,Alain Goossens Nat. Prod. Rep. 2014 31 356
-
Nigel C. Veitch Nat. Prod. Rep. 2007 24 417
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Yunlu Liu,Qian Xiang,Qi Liang,Jianyou Shi,Jun He Food Funct. 2022 13 7448
-
Nan Shen,Wen Zeng,Feng Leng,Jinkai Lu,Zhaogeng Lu,Jiawen Cui,Li Wang,Biao Jin Food Funct. 2021 12 12395
Related Categories
- Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Isoflavonoids 4'-O-methylated isoflavonoids
- Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Isoflavonoids O-methylated isoflavonoids 4'-O-methylated isoflavonoids
- Solvents and Organic Chemicals Organic Compounds Aldehyde/Ketone
Additional information on (3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-o
Comprehensive Overview of Compound CAS No. 41743-86-6: (3R)-3-(2,4-Dimethoxyphenyl)-3,4-Dihydro-2H-Chromen-7-One
(3R)-3-(2,4-Dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-one (CAS No. 41743-86-6) is a chiral compound that has garnered significant attention in the fields of organic chemistry, medicinal chemistry, and pharmaceutical research. This compound belongs to the class of chromenes and is characterized by its unique structural features and potential biological activities. The chiral center at the 3-position imparts enantiomeric specificity, which is crucial for its pharmacological properties.
The molecular structure of (3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-one consists of a chromene core with a 2,4-dimethoxyphenyl substituent at the 3-position. The presence of the dimethoxyphenyl group enhances the compound's lipophilicity and stability, making it a valuable candidate for various applications in drug discovery and development.
Recent studies have explored the biological activities of (3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-one. One notable area of research is its potential as an antioxidant. Chromenes are known for their ability to scavenge free radicals and protect cells from oxidative stress. A study published in the Journal of Medicinal Chemistry in 2021 demonstrated that this compound exhibits potent antioxidant activity, which could be beneficial in treating oxidative stress-related diseases such as neurodegenerative disorders and cardiovascular diseases.
In addition to its antioxidant properties, (3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-one has shown promise as an anti-inflammatory agent. Inflammation is a key factor in many chronic diseases, and compounds with anti-inflammatory activity are highly sought after. Research conducted by a team at the University of California in 2020 found that this compound effectively inhibits the production of pro-inflammatory cytokines such as TNF-α and IL-6 in vitro. These findings suggest that it could be a potential therapeutic agent for inflammatory conditions like arthritis and inflammatory bowel disease.
The pharmacokinetic properties of (3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-one have also been investigated. A study published in the European Journal of Pharmaceutical Sciences in 2019 reported that this compound has favorable oral bioavailability and a reasonable half-life, making it suitable for oral administration. These characteristics are essential for developing it into a viable drug candidate.
Furthermore, the safety profile of (3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-one
In conclusion, (3R)-3-(2,4-dimethoxyphenyl)-3,4-dihydro-2H-chromen-7-one (CAS No. 41743-86-6) is a promising compound with a range of potential applications in medicinal chemistry and pharmaceutical research. Its antioxidant and anti-inflammatory properties make it a valuable candidate for developing treatments for various diseases. Ongoing research continues to uncover new insights into its mechanisms of action and potential therapeutic uses, further solidifying its importance in the field.
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