Cas no 4143-63-9 (4'-Hydroxyflavone)

4'-Hydroxyflavone is a flavonoid derivative characterized by the presence of a hydroxyl group at the 4' position of the phenyl ring. This compound is of interest in biochemical and pharmacological research due to its potential as a modulator of enzyme activity and cellular signaling pathways. Its structural features make it a useful intermediate in the synthesis of more complex flavonoid analogs. The compound exhibits moderate solubility in organic solvents, facilitating its use in experimental applications. Studies suggest it may interact with cytochrome P450 enzymes, making it relevant for investigating metabolic processes. Its purity and stability under standard laboratory conditions further enhance its utility in research settings.
4'-Hydroxyflavone structure
4'-Hydroxyflavone structure
Product Name:4'-Hydroxyflavone
CAS No:4143-63-9
MF:C15H10O3
MW:238.238104343414
MDL:MFCD00017687
CID:329511
PubChem ID:229016
Update Time:2025-08-02

4'-Hydroxyflavone Chemical and Physical Properties

Names and Identifiers

    • 4H-1-Benzopyran-4-one,2-(4-hydroxyphenyl)-
    • 4'-Hydroxyflavone
    • 4'-HYDROXYFLAVANONE
    • 4'-monohydroxyflavone
    • Flavone,4'-hydroxy
    • 2-(4-Hydroxyphenyl)-4H-1-benzopyran-4-one
    • 2-(4-Hydroxyphenyl)-4H-chromen-4-one
    • 2-(4-hydroxyphenyl)chromen-4-one
    • 4H-1-Benzopyran-4-one, 2-(4-hydroxyphenyl)-
    • 8I6VZR0K67
    • SHGLJXBLXNNCTE-UHFFFAOYSA-N
    • 2H-1-Benzopyran-2-one, 2-(4-hydroxyphenyl)-
    • Flavone, 4'-hydroxy-
    • 4kzq
    • NSC22357
    • 4''-hydroxyflavone
    • ChemDiv2_003923
    • Oprea1_206844
    • MLS001049036
    • HMS2271H09
    • HMS1380C07
    • BDBM50011446
    • NS
    • STL560667
    • H1638
    • NSC 22357
    • CHEMBL327209
    • NS00116163
    • AKOS003623541
    • SR-01000471683-1
    • SMR000387049
    • 2-(4-Hydroxy-phenyl)-chromen-4-one
    • IDI1_002638
    • Q27270572
    • SR-01000471683
    • FT-0635151
    • CS-0358728
    • SCHEMBL127446
    • DTXSID70877680
    • 4-OXO-4-(2-OXO-1,2-DIPHENYLETHOXY)BUTANOICACID
    • 4143-63-9
    • NSC-22357
    • T72445
    • CCG-18944
    • MFCD00017687
    • NCGC00246218-01
    • EU-0042507
    • UNII-8I6VZR0K67
    • FS-10640
    • DB-049757
    • 4'-METHOXYFLAVONE_met003
    • MDL: MFCD00017687
    • Inchi: 1S/C15H10O3/c16-11-7-5-10(6-8-11)15-9-13(17)12-3-1-2-4-14(12)18-15/h1-9,16H
    • InChI Key: SHGLJXBLXNNCTE-UHFFFAOYSA-N
    • SMILES: O1C2C=CC=CC=2C(C=C1C1C=CC(=CC=1)O)=O

Computed Properties

  • Exact Mass: 238.06300
  • Monoisotopic Mass: 238.063
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 1
  • Complexity: 353
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.2
  • Topological Polar Surface Area: 46.5

Experimental Properties

  • Density: 1.34
  • Boiling Point: 425.8°Cat760mmHg
  • Flash Point: 165.7°C
  • Refractive Index: 1.666
  • PSA: 50.44000
  • LogP: 3.16560
  • λmax: 325(MeOH)(lit.)

4'-Hydroxyflavone Security Information

4'-Hydroxyflavone Customs Data

  • HS CODE:2914501900
  • Customs Data:

    China Customs Code:

    2914501900

    Overview:

    2914501900 Other ketophenols.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:5.5%.general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, Acetone declared packaging

    Summary:

    2914501900 other ketone-phenols.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:5.5%.General tariff:30.0%

4'-Hydroxyflavone Pricemore >>

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4'-Hydroxyflavone Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:4143-63-9)4'-Hydroxyflavone
Order Number:A901138
Stock Status:in Stock
Quantity:25mg/50mg/100mg/500mg/5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 12:07
Price ($):204.0/305.0/454.0/1019.0/232.0

Additional information on 4'-Hydroxyflavone

Exploring the Potential of 4'-Hydroxyflavone (CAS No. 4143-63-9): A Versatile Flavonoid with Promising Applications

4'-Hydroxyflavone (CAS No. 4143-63-9) is a naturally occurring flavonoid that has garnered significant attention in recent years due to its diverse biological activities and potential health benefits. As a member of the flavone family, this compound is structurally characterized by a 15-carbon skeleton consisting of two phenyl rings (A and B) and a heterocyclic ring (C). The presence of a hydroxyl group at the 4' position of the B-ring distinguishes 4'-Hydroxyflavone from other flavones and contributes to its unique chemical properties.

The growing interest in natural compounds and plant-derived bioactive molecules has positioned 4'-Hydroxyflavone as a subject of intense research. Scientists are particularly interested in its potential as an antioxidant, with studies suggesting it may help combat oxidative stress – a key factor in aging and various chronic conditions. The compound's ability to modulate cellular signaling pathways has also made it a candidate for investigating its effects on inflammation and metabolic disorders, topics that are currently trending in health and wellness discussions.

From a chemical perspective, 4'-Hydroxyflavone (CAS No. 4143-63-9) exhibits interesting properties that make it valuable for both research and potential applications. The compound appears as a yellow crystalline powder with a molecular formula of C15H10O3 and a molecular weight of 238.24 g/mol. Its melting point ranges between 250-252°C, and it demonstrates limited solubility in water but better solubility in organic solvents like ethanol and dimethyl sulfoxide (DMSO). These physical characteristics are important considerations for researchers working with this compound in laboratory settings.

The pharmacological potential of 4'-Hydroxyflavone has become a hot topic in nutraceutical research. Preliminary studies have explored its possible neuroprotective effects, with particular interest in its ability to cross the blood-brain barrier. This property makes it a compelling subject for research into cognitive health and age-related neurological conditions, areas that consistently rank high in public health searches. Additionally, its potential interactions with various enzyme systems have led to investigations into its possible role in metabolic regulation and cellular protection.

In the field of cosmeceuticals, 4'-Hydroxyflavone has attracted attention for its potential skin benefits. The compound's UV-absorbing properties and antioxidant capacity make it an interesting candidate for anti-aging formulations and photoprotective products. With consumers increasingly seeking natural alternatives in skincare, research into flavonoids like 4'-Hydroxyflavone has gained momentum, addressing common search queries about natural skincare ingredients and plant-based anti-aging solutions.

The analytical characterization of 4'-Hydroxyflavone (CAS No. 4143-63-9) typically involves techniques such as high-performance liquid chromatography (HPLC), mass spectrometry, and nuclear magnetic resonance (NMR) spectroscopy. These methods are crucial for quality control in research applications and potential product development. The compound's purity is particularly important given the growing emphasis on standardized botanical extracts in both research and consumer products.

From a commercial perspective, the market for bioactive flavonoids like 4'-Hydroxyflavone is expanding rapidly. The global interest in functional foods and dietary supplements has created new opportunities for research into this compound's potential applications. Manufacturers and researchers alike are exploring ways to enhance the bioavailability of 4'-Hydroxyflavone, addressing one of the most common challenges in flavonoid research and a frequent topic in scientific literature.

Safety considerations for 4'-Hydroxyflavone are an important aspect of current research. While flavonoids are generally regarded as safe components of many foods, the specific safety profile of isolated 4'-Hydroxyflavone at various concentrations continues to be investigated. This aligns with consumer concerns about supplement safety and natural product efficacy, which are among the top-searched topics in the health and wellness sector.

The future research directions for 4'-Hydroxyflavone (CAS No. 4143-63-9) appear promising and diverse. Scientists are particularly interested in exploring its potential synergistic effects with other phytochemicals, as well as its possible role in gut microbiome modulation – a rapidly growing area of scientific inquiry. The compound's relatively simple structure also makes it an attractive scaffold for medicinal chemistry modifications aimed at enhancing specific biological activities.

In conclusion, 4'-Hydroxyflavone represents an intriguing example of nature's chemical diversity with significant potential for various applications. From its basic chemical properties to its emerging biological activities, this compound continues to fascinate researchers across multiple disciplines. As scientific understanding of flavonoid bioactivity deepens and consumer interest in plant-based health solutions grows, 4'-Hydroxyflavone is likely to remain an important subject of research and development in the coming years.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:4143-63-9)4'-Hydroxyflavone
A901138
Purity:99%/99%/99%/99%/99%
Quantity:25mg/50mg/100mg/500mg/5g
Price ($):204.0/305.0/454.0/1019.0/232.0
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