Cas no 4134-56-9 (S-Butyl-D-cysteine)

S-Butyl-D-cysteine is a chiral cysteine derivative characterized by the presence of a butylthio group at the sulfur atom of the D-cysteine backbone. This modification enhances its lipophilicity, making it valuable in peptide synthesis and pharmaceutical applications where improved membrane permeability is desired. The D-configuration offers metabolic stability, reducing susceptibility to enzymatic degradation. Its unique structure facilitates selective thiol-disulfide exchange reactions, useful in bioconjugation and protein engineering. The compound is typically employed as a building block in asymmetric synthesis and as a ligand in metal-catalyzed reactions. High purity grades ensure reproducibility in research and industrial processes. Proper handling under inert conditions is recommended due to its thiol reactivity.
S-Butyl-D-cysteine structure
S-Butyl-D-cysteine structure
Product Name:S-Butyl-D-cysteine
CAS No:4134-56-9
MF:C7H15NO2S
MW:177.2645008564
CID:44780
PubChem ID:13817366
Update Time:2025-11-01

S-Butyl-D-cysteine Chemical and Physical Properties

Names and Identifiers

    • S-Butyl-D-cysteine
    • (R)-2-Amino-3-(S-butylthio)propanoic acid
    • D-S-BUTYLCYSTEINE
    • S-n-Butyl-L-cysteine
    • (R)-S-butylcysteine
    • AG-F-47183
    • Alanine,3-(butylthio)-, L- (8CI)
    • CTK1D7939
    • L-2-Amino-3-butylmercapto-propionsaeure
    • l-Cysteine, S-butyl-
    • S-(n-Butyl)-L-cysteine
    • S-butyl cysteine
    • S-Butyl-L-cystein
    • S-Butyl-L-cysteine
    • SCHEMBL1157599
    • H-Cys(butyl)-OH
    • (S)-Butyl-L-Cys
    • Butylcysteine #
    • (R)-2-amino-3-(butylthio)propanoic acid
    • (2R)-2-amino-3-butylsulfanylpropanoic acid
    • QY5BX63TZ2
    • DTXSID30194300
    • ALANINE, 3-(BUTYLTHIO)-, L-
    • UNII-QY5BX63TZ2
    • (2R)-2-Amino-3-butylsulfanyl-propanoic acid
    • 4134-56-9
    • S-Butylcysteine
    • FFGXHYXBEDRCNM-LURJTMIESA-N
    • AKOS017343284
    • (2R)-2-amino-3-(butylsulfanyl)propanoic acid
    • EN300-7028645
    • MDL: MFCD00045867
    • Inchi: 1S/C7H15NO2S/c1-2-3-4-11-5-6(8)7(9)10/h6H,2-5,8H2,1H3,(H,9,10)/t6-/m0/s1
    • InChI Key: FFGXHYXBEDRCNM-LURJTMIESA-N
    • SMILES: S(C[C@@H](C(=O)O)N)CCCC

Computed Properties

  • Exact Mass: 177.08245
  • Monoisotopic Mass: 177.082349
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 6
  • Complexity: 130
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 50.3
  • XLogP3: -1.5

Experimental Properties

  • Density: 1.092
  • Boiling Point: 267.6 °C at 760 mmHg
  • Flash Point: 115.6 °C
  • Refractive Index: 1.496
  • PSA: 63.32
  • LogP: 1.63190

S-Butyl-D-cysteine Pricemore >>

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SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1945889-1g
s-Butyl-l-cysteine
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S-Butyl-D-cysteine Related Literature

Additional information on S-Butyl-D-cysteine

S-Butyl-D-cysteine: A Comprehensive Overview of CAS No. 4134-56-9

S-Butyl-D-cysteine (CAS No. 4134-56-9) is a unique compound that has garnered significant attention in the fields of chemistry, biochemistry, and pharmaceutical research. This compound is a derivative of D-cysteine, an amino acid with a thiol group, which plays a crucial role in various biological processes. The addition of a butyl group to the thiol moiety imparts distinct chemical and biological properties, making S-Butyl-D-cysteine an intriguing subject for scientific investigation.

The chemical structure of S-Butyl-D-cysteine consists of a central carbon atom bonded to an amino group, a carboxylic acid group, and a thiol group substituted with a butyl chain. This structural configuration confers the compound with unique reactivity and solubility characteristics. The presence of the butyl group enhances the lipophilicity of the molecule, which can influence its cellular uptake and distribution. These properties are particularly relevant in the context of drug design and delivery systems.

Recent studies have explored the potential applications of S-Butyl-D-cysteine in various therapeutic areas. One notable area of research is its role as a precursor in the synthesis of more complex molecules with therapeutic potential. For instance, S-Butyl-D-cysteine can be used as a building block in the development of novel antioxidants and anti-inflammatory agents. These compounds are essential in combating oxidative stress and inflammation, which are underlying factors in numerous diseases such as cardiovascular disorders, neurodegenerative diseases, and cancer.

In addition to its use as a synthetic intermediate, S-Butyl-D-cysteine has been investigated for its direct biological activities. Research has shown that it possesses antioxidant properties, which can help protect cells from damage caused by reactive oxygen species (ROS). The ability to scavenge ROS is particularly important in maintaining cellular homeostasis and preventing oxidative damage to DNA, proteins, and lipids. This makes S-Butyl-D-cysteine a promising candidate for developing new therapeutic strategies to combat oxidative stress-related conditions.

Another area of interest is the potential of S-Butyl-D-cysteine as a protective agent against heavy metal toxicity. Heavy metals such as lead, mercury, and cadmium are known to cause significant health problems by disrupting cellular functions and inducing oxidative stress. Studies have demonstrated that S-Butyl-D-cysteine can effectively chelate these metals, thereby reducing their toxicity and promoting their excretion from the body. This property could be harnessed to develop new treatments for heavy metal poisoning.

The pharmacokinetic properties of S-Butyl-D-cysteine have also been studied to understand its behavior in biological systems. Research has shown that it exhibits good bioavailability and stability under physiological conditions. These characteristics are crucial for ensuring that the compound reaches its intended target site within the body and remains active for an extended period. The favorable pharmacokinetic profile of S-Butyl-D-cysteine makes it an attractive candidate for further preclinical and clinical evaluation.

In conclusion, S-Butyl-D-cysteine (CAS No. 4134-56-9) is a versatile compound with a wide range of potential applications in chemistry, biochemistry, and pharmaceutical research. Its unique chemical structure and biological activities make it a valuable tool for developing new therapeutic agents and understanding fundamental biological processes. Ongoing research continues to uncover new insights into the properties and applications of this compound, highlighting its significance in advancing scientific knowledge and improving human health.

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