• 1. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
• 2. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 3. Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation
  Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
• 4. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 5. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzophenones

Introduction to Bis(3,4-dimethoxyphenyl)methanone (CAS No. 4131-03-7)

Bis(3,4-dimethoxyphenyl)methanone, with the chemical formula C₁₇H₁₈O₂ and CAS number 4131-03-7, is a significant compound in the field of organic chemistry and pharmaceutical research. This review provides an in-depth exploration of its chemical properties, synthesis methods, and recent applications in medicinal chemistry.

The compound is characterized by a methanone core substituted with two 3,4-dimethoxyphenyl groups. This structural arrangement imparts unique electronic and steric properties, making it a valuable intermediate in the synthesis of more complex molecules. The presence of methoxy groups enhances the solubility and reactivity of the compound, facilitating its use in various chemical transformations.

In recent years, Bis(3,4-dimethoxyphenyl)methanone has garnered attention for its potential applications in the development of pharmaceuticals. Its aromatic structure and functional groups make it a versatile building block for drug discovery. Researchers have explored its utility in creating novel bioactive molecules that exhibit promising pharmacological effects.

One of the most intriguing aspects of Bis(3,4-dimethoxyphenyl)methanone is its role in the synthesis of heterocyclic compounds. These derivatives have shown significant promise in treating various diseases, including cancer and neurological disorders. The methoxy groups on the phenyl rings can be selectively modified through various chemical reactions, allowing for the creation of a diverse array of derivatives with tailored biological activities.

The synthesis of Bis(3,4-dimethoxyphenyl)methanone typically involves the condensation of dimethoxybenzaldehyde with acetone or an equivalent carbonyl compound. This reaction proceeds under mild conditions and yields high yields of the desired product. The simplicity of the synthesis makes it an attractive choice for both academic research and industrial applications.

Recent advancements in green chemistry have also influenced the synthesis of Bis(3,4-dimethoxyphenyl)methanone. Researchers are increasingly employing solvent-free conditions and catalytic methods to improve efficiency and reduce environmental impact. These innovations not only enhance the sustainability of the process but also contribute to cost-effective production.

The pharmacological potential of Bis(3,4-dimethoxyphenyl)methanone has been extensively studied in recent years. Several research groups have reported its efficacy as an antioxidant, anti-inflammatory, and antimicrobial agent. These findings suggest that it may have therapeutic applications in treating a wide range of diseases.

In particular, studies have shown that derivatives of Bis(3,4-dimethoxyphenyl)methanone exhibit potent inhibitory activity against various enzymes involved in disease pathogenesis. For instance, some derivatives have demonstrated significant inhibition of kinases and other enzymes implicated in cancer progression. This has opened up new avenues for developing targeted therapies against this devastating disease.

The compound's ability to cross cell membranes also makes it an attractive candidate for drug delivery systems. Researchers are exploring its use as a carrier molecule for delivering therapeutic agents to specific sites within the body. This approach could enhance drug efficacy while minimizing side effects.

The future prospects for Bis(3,4-dimethoxyphenyl)methanone are promising, with ongoing research expected to uncover new applications and refine existing synthetic methods. As our understanding of its chemical properties and biological activities continues to grow, this compound is poised to play a crucial role in the development of next-generation pharmaceuticals.

• 6100-74-9(1-(3-Hydroxy-4-methoxyphenyl)ethanone)
• 55363-58-1(Methanone, phenyl(3,4,5-trimethoxyphenyl)-)
• 792-57-4(Methanone, (3,4-dimethoxyphenyl)(3-methoxyphenyl)-)
• 4038-14-6(3,4-Dimethoxybenzophenone)
• 134612-39-8(4-Hydroxy-3-methoxy-4'-methylbenzophenone)
• 1131-62-0(3',4'-Dimethoxyacetophenone)
• 350818-54-1(3',4'-Dimethoxyacetophenone-d3 (methyl-d3))
• 22699-97-4(Methanone,(3,4-dimethoxyphenyl)(3,4,5-trimethoxyphenyl)-)
• 80404-23-5(Acetovanillone-d3)
• 498-02-2(Apocynin)