Cas no 4124-31-6 (Trichloroacetic anhydride)
Trichloroacetic anhydride (C4Cl6O3) is a reactive chemical compound primarily used as an acylating agent in organic synthesis. Its high reactivity stems from the electron-withdrawing effect of the trichloromethyl groups, making it effective for introducing trichloroacetyl functionalities. The compound is particularly valuable in peptide synthesis and the preparation of trichloroacetate esters. It exhibits strong electrophilic properties, facilitating reactions with alcohols, amines, and other nucleophiles. Trichloroacetic anhydride is also employed in the cleavage of protecting groups and as a dehydrating agent. Handling requires caution due to its corrosive nature and moisture sensitivity. Proper storage under anhydrous conditions is essential to maintain stability.
Trichloroacetic anhydride structure
Product Name:Trichloroacetic anhydride
CAS No:4124-31-6
MF:C4Cl6O3
MW:308.758996009827
MDL:MFCD00000793
CID:84935
PubChem ID:87576634
Update Time:2025-10-14
Trichloroacetic anhydride Chemical and Physical Properties
Names and Identifiers
-
- trichloroacetic anhydride
- (2,2,2-trichloroacetyl) 2,2,2-trichloroacetate
- Perchloroacetic Anhydride
- Acetic acid, trichloro-, anhydride
- MEFKFJOEVLUFAY-UHFFFAOYSA-N
- Trichloroacetyl 2,2,2-trichloroacetate
- Acetic acid, 2,2,2-trichloro-, 1,1'-anhydride
- Trichloroacetic anhydride, 95%
- trichloroaceticanhydride
- Bis(trichloroacetic)anhydride
- trichloroacetic acid anhydride
- Trichloroacetic anhydride, 99%
- 2,2,2-trichloroacetic anhydride
- Trichloroacetic anhydride
-
- MDL： MFCD00000793
- Inchi： 1S/C4Cl6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10
- InChI Key： MEFKFJOEVLUFAY-UHFFFAOYSA-N
- SMILES： ClC(C(=O)OC(C(Cl)(Cl)Cl)=O)(Cl)Cl
- BRN： 980355
Computed Properties
- Exact Mass: 305.79800
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 13
- Rotatable Bond Count: 2
- Complexity: 201
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 3.6
- Topological Polar Surface Area: 43.4
Experimental Properties
- Color/Form: Not available
- Density: 1.69?g/mL?at 25?°C(lit.)
- Boiling Point: 116°C/23mmHg(lit.)
- Flash Point: 98-100°C/11mm
- Refractive Index: n20/D 1.484(lit.)
- Solubility: Miscible with ether and acetic acid.
- Stability/Shelf Life: Stable. Moisture sensitive - store under dry atmosphere. Incompatible with strong bases, strong oxidizing agents.
- PSA: 43.37000
- LogP: 2.79660
- Sensitiveness: Moisture Sensitive
- Solubility: Not available
Trichloroacetic anhydride Security Information
-
Symbol:
- Prompt：dangerous
- Signal Word：Danger
- Hazard Statement： H290-H314
- Warning Statement： P234-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P390-P405-P406-P501
- Hazardous Material transportation number：UN 3265 8/PG 2
- WGK Germany：3
- Hazard Category Code： 22-35
- Safety Instruction： S26-S36/37/39-S45
- FLUKA BRAND F CODES：10-21
-
Hazardous Material Identification：
- HazardClass：8
- PackingGroup：II
- TSCA：Yes
- Safety Term：8
- Packing Group：II
- Risk Phrases：R35
- Packing Group：II
- Hazard Level：8
Trichloroacetic anhydride Customs Data
- HS CODE：2915900090
- Customs Data：
China Customs Code:
2915900090Overview:
2915900090. Other saturated acyclic monocarboxylic acids and their anhydrides(Acyl halide\Peroxygenation)Chemicals\Peroxy acid and its halogenation\nitrification\sulfonation\Nitrosative derivative. VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods). MFN tariff:5.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Regulatory conditions:
A.Customs clearance form for Inbound Goods
B.Customs clearance form for outbound goodsInspection and quarantine category:
R.Sanitary supervision and inspection of imported food
S.Sanitary supervision and inspection of exported food
M.Import commodity inspection
N.Export commodity inspectionSummary:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%
Trichloroacetic anhydride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 367710-25G |
Trichloroacetic anhydride |
4124-31-6 | 95% | 25g |
￥1032.22 | 2023-12-07 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 367710-100G |
Trichloroacetic anhydride |
4124-31-6 | 95% | 100g |
￥3236.05 | 2023-12-07 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | SA00432-25g |
TRICHLOROACETICANHYDRIDE |
4124-31-6 | 95% | 25g |
￥1808.0 | 2024-07-19 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | SA00432-100g |
TRICHLOROACETICANHYDRIDE |
4124-31-6 | 95% | 100g |
￥5738.0 | 2024-07-19 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | X71295-5g |
TRICHLOROACETICANHYDRIDE |
4124-31-6 | ≥97% | 5g |
￥158.0 | 2023-09-05 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | X71295-1g |
TRICHLOROACETICANHYDRIDE |
4124-31-6 | 1g |
￥48.0 | 2021-09-07 | ||
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | T161589-1g |
Trichloroacetic anhydride |
4124-31-6 | 97% | 1g |
￥49.90 | 2023-08-31 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | T161589-250g |
Trichloroacetic Anhydride |
4124-31-6 | >97.0% | 250g |
￥2,250.00 | 2021-05-24 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | T161589-25G |
Trichloroacetic Anhydride |
4124-31-6 | >97.0% | 25G |
￥272.00 | 2021-05-24 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | T161589-50g |
Trichloroacetic Anhydride |
4124-31-6 | >97.0% | 50g |
￥599.00 | 2021-05-24 |
Trichloroacetic anhydride Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:4124-31-6)Trichloroacetic anhydride
Order Number:A1204910
Stock Status:in Stock
Quantity:250g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 15:57
Price ($):184.0
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:4124-31-6)三 酐
Order Number:LE1695993
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:34
Price ($):discuss personally
Email:[email protected]
Trichloroacetic anhydride Related Literature
-
Stephan D. Stamatov,Jacek Stawinski Org. Biomol. Chem. 2010 8 463
-
Anh Thu Nguyen Tran,Zhiyuan Wu,Duy T. M. Chung,Phattananawee Nalaoh,Jonathan S. Lindsey New J. Chem. 2023 47 13626
-
Yupeng Cao,Xiangyang Lin,Jun Yang,Xuedong Gong,Guijuan Fan,Haifeng Huang New J. Chem. 2019 43 5441
-
Stephan D. Stamatov,Jacek Stawinski Org. Biomol. Chem. 2007 5 3787
-
Mohammad S. Khajavi,Fatemeh Sefidkon,S. S. Sadat Hosseini J. Chem. Res. (S) 1998 724
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