• 1. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 2. Distributed research: a new paradigm for undergraduate research and global problem solving?
  Bruce Parkinson Energy Environ. Sci., 2010,3, 509-511
• 3. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
• 4. Establishment and implications of a characterization method for magnetic nanoparticle using cell tracking velocimetry and magnetic susceptibility modified solutions
  Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
• 5. Fe3O4@PANI: a magnetic polyaniline nanomaterial for highly efficient and handy enrichment of intact N-glycopeptides??
  Zhizhen Lai,Mo Zhang,Jinyu Zhou,Tianjing Chen,Dan Li,Xuejing Shen,Jia Liu,Jiang Zhou,Zhili Li Analyst, 2021,146, 4261-4267

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Coumarans Coumarans
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Coumarans

5-Bromo-2,3-dihydrobenzofuran-7-carboxylic Acid: A Comprehensive Overview

The compound 5-Bromo-2,3-dihydrobenzofuran-7-carboxylic Acid, with the CAS number 41177-72-4, is a fascinating molecule that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound belongs to the class of benzofuran derivatives, which are known for their diverse biological activities and structural versatility. The presence of the bromine atom at position 5 and the carboxylic acid group at position 7 makes this molecule unique, offering potential applications in drug discovery and material science.

Recent studies have highlighted the importance of benzofuran derivatives in medicinal chemistry. The 5-Bromo-2,3-dihydrobenzofuran-7-carboxylic Acid structure has been explored for its potential as an anti-inflammatory agent. Researchers have found that this compound exhibits significant inhibitory effects on cyclooxygenase (COX) enzymes, which are key players in inflammation and pain pathways. This finding underscores its potential as a lead compound for developing novel anti-inflammatory drugs.

In addition to its pharmacological properties, the synthesis of 5-Bromo-2,3-dihydrobenzofuran-7-carboxylic Acid has been optimized using green chemistry principles. Traditional methods often involved multi-step reactions with hazardous reagents, but recent advancements have introduced more efficient and environmentally friendly approaches. For instance, microwave-assisted synthesis has been employed to streamline the reaction process, reducing both time and energy consumption.

The structural uniqueness of this compound also makes it a valuable substrate for further chemical modifications. Scientists have explored its use as a building block for constructing more complex molecules with enhanced bioactivity. For example, researchers have attached various functional groups to the carboxylic acid moiety to enhance solubility and improve pharmacokinetic profiles.

From an analytical standpoint, the characterization of 5-Bromo-2,3-dihydrobenzofuran-7-carboxylic Acid has been achieved using advanced spectroscopic techniques such as nuclear magnetic resonance (NMR) and mass spectrometry (MS). These methods provide detailed insights into the molecular structure and purity of the compound, ensuring its reliability for further studies.

In conclusion, 5-Bromo-2,3-dihydrobenzofuran-7-carboxylic Acid represents a promising molecule with diverse applications in medicinal chemistry and beyond. Its unique structure, coupled with recent advancements in synthesis and biological evaluation, positions it as a valuable asset in both academic research and industrial development.

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• 60783-92-8(5-Bromo-2-butoxybenzoic Acid)
• 60783-90-6(5-Bromo-2-ethoxybenzoic Acid)
• 88952-04-9(Benzoic acid, 2-methoxy-, 2-acetyl-4-bromophenyl ester)
• 252921-20-3(7-Benzofurancarboxylic acid, 5-bromo-2,3-dihydro-, methyl ester)
• 269731-55-7(4-Bromo-2-propoxybenzoic acid)
• 281678-73-7(5-Bromo-2,3-dihydrobenzobfuran-7-carbaldehyde)
• 60783-91-7(5-Bromo-2-propoxybenzoic Acid)
• 138572-65-3(1-Benzoxepin-9-carboxylic acid, 7-bromo-2,3,4,5-tetrahydro-)
• 335671-77-7(5-Benzofurancarboxylic acid, 7-bromo-2,3-dihydro-)