• 1. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 2. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
• 3. Exchanged ligands on the surface of a giant cluster: [(MoO3)176(H2O)63(CH3OH)17Hn](32 – n)–
  Chem. Commun., 1998, 1501-1502
• 4. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 5. Evolution study of photo-synthesized gold nanoparticles by spectral deconvolution model: a quantitative approach
  Chung-Sung Yang,Mong-Shian Shih,Fang-Yi Chang New J. Chem., 2006,30, 729-735

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives N-phenylthioureas

Professional Introduction to N-Methyl-N-phenylthiourea (CAS No. 4104-75-0)

N-Methyl-N-phenylthiourea, with the chemical formula C₆H₇NS, is a significant compound in the field of pharmaceutical and agrochemical research. Its CAS number, 4104-75-0, uniquely identifies it in scientific literature and databases. This compound has garnered attention due to its versatile applications and the potential it holds for developing novel therapeutic agents.

The structural integrity of N-Methyl-N-phenylthiourea makes it a valuable intermediate in organic synthesis. The presence of both a methyl group and a phenyl group attached to the thiourea core enhances its reactivity, making it a preferred choice for various chemical transformations. These properties have been exploited in the synthesis of complex molecules, particularly in the development of drugs targeting neurological disorders.

In recent years, researchers have been exploring the pharmacological potential of N-Methyl-N-phenylthiourea. Its ability to interact with biological targets has led to its investigation as a possible candidate for treating conditions such as epilepsy and Parkinson's disease. Studies have shown that this compound can modulate neurotransmitter activity, which is crucial for managing these neurological conditions.

One of the most compelling aspects of N-Methyl-N-phenylthiourea is its role in the development of agrochemicals. The compound's efficacy as a pesticide and herbicide has been well-documented. Its mode of action involves disrupting essential metabolic pathways in pests, thereby providing effective control over agricultural pests. This has made it a subject of interest for sustainable farming practices.

The synthesis of N-Methyl-N-phenylthiourea involves several well-established chemical reactions. The process typically begins with the condensation of methylamine with phenylisothiocyanate, followed by purification steps to obtain high-purity material. Advances in synthetic methodologies have improved the yield and purity of this compound, making it more accessible for research and industrial applications.

The safety profile of N-Methyl-N-phenylthiourea is another critical consideration. While it is not classified as a hazardous substance, proper handling procedures must be followed to ensure safety. Personal protective equipment (PPE) such as gloves and lab coats should be worn during handling, and adequate ventilation should be maintained to minimize exposure to vapors.

Recent studies have also highlighted the compound's potential in material science. N-Methyl-N-phenylthiourea has been investigated for its role in creating novel polymers and coatings due to its ability to form stable complexes with metal ions. These complexes exhibit enhanced mechanical properties, making them suitable for high-performance materials.

The environmental impact of using N-Methyl-N-phenylthiourea is an area of ongoing research. Efforts are being made to develop greener synthetic routes that minimize waste and reduce environmental footprint. Additionally, studies are being conducted to assess the biodegradability of this compound, ensuring that its use does not contribute to long-term environmental pollution.

In conclusion, N-Methyl-N-phenylthiourea (CAS No. 4104-75-0) is a multifaceted compound with significant applications in pharmaceuticals, agrochemicals, and material science. Its unique chemical properties make it a valuable tool for researchers and industry professionals alike. As research continues to uncover new applications and improve synthetic methods, this compound is poised to play an even greater role in advancing scientific and industrial progress.

• 1519-70-6(1,4-Phenylenebis(2-thiourea))
• 22283-43-8(N-4-(dimethylamino)phenylthiourea)
• 26763-62-2(Thiourea, diphenyl-)
• 35696-78-7(Thiourea,N-methyl-N-(4-methylphenyl)-)
• 2740-95-6(Thiourea,N,N'-dimethyl-N-phenyl-)
• 5779-20-4(Thiourea, N-[4-(dimethylamino)phenyl]-N'-phenyl-)
• 3898-08-6(1,1-Diphenyl-2-thiourea)
• 103-85-5(Phenylthiourea)
• 13991-81-6(Thiourea,N,N'-bis[4-(dimethylamino)phenyl]-)
• 52777-00-1(Thiourea, methylphenyl-)