• 1. Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450BM3) variant
  Christopher J. C. Whitehouse,Wen Yang,Jake A. Yorke,Henry G. Tufton,Lydia C. I. Ogilvie,Stephen G. Bell,Weihong Zhou,Mark Bartlam,Zihe Rao,Luet-Lok Wong Dalton Trans. 2011 40 10383
• 2. Copper-catalyzed oxidative aromatization of 2-cyclohexen-1-ones to phenols in the presence of catalytic hydrogen bromide under molecular oxygen
  Kotaro Kikushima,Yuta Nishina RSC Adv. 2013 3 20150

• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenols 1-hydroxy-4-unsubstituted benzenoids

Phenol, 3-butyl-

Phenol, 3-butyl-, also known by its CAS number 4074-43-5, is an organic compound that has garnered significant attention in both academic and industrial research. This compound is a derivative of phenol, with a butyl group attached at the third position of the benzene ring. Its chemical structure makes it a versatile molecule with applications in various fields, including materials science, pharmaceuticals, and catalysis.

The synthesis of Phenol, 3-butyl- typically involves the alkylation of phenol using appropriate alkylating agents. Recent advancements in catalytic methods have enabled more efficient and selective syntheses, reducing byproducts and enhancing yield. For instance, researchers have explored the use of solid acid catalysts and microwave-assisted techniques to streamline the production process. These innovations not only improve the economic viability of the compound but also align with the growing demand for sustainable chemical manufacturing practices.

In terms of physical properties, Phenol, 3-butyl- exhibits a melting point of approximately 15°C and a boiling point around 180°C under standard conditions. Its solubility in organic solvents such as dichloromethane and diethyl ether makes it suitable for various chemical reactions and formulations. The compound's ability to form stable derivatives has been leveraged in the development of advanced materials, including thermoplastics and high-performance polymers.

The application of Phenol, 3-butyl- in materials science is particularly noteworthy. It serves as a precursor for synthesizing polyurethanes and epoxy resins, which are widely used in construction and automotive industries. Recent studies have highlighted its role in creating lightweight yet durable composites that can withstand harsh environmental conditions. These materials are increasingly being adopted in aerospace applications due to their exceptional mechanical properties.

In the field of biomedicine, Phenol, 3-butyl- has shown potential as an antimicrobial agent. Researchers have demonstrated its effectiveness against a range of bacterial strains, including drug-resistant pathogens. This property makes it a promising candidate for developing new generations of antiseptics and wound care products. Furthermore, its ability to inhibit biofilm formation has opened avenues for combating chronic infections associated with medical devices.

The catalytic properties of Phenol, 3-butyl- have also been explored extensively. It has been used as a ligand in transition metal catalysts for various organic reactions, such as Heck coupling and Suzuki-Miyaura cross-coupling. Recent breakthroughs in asymmetric catalysis have further expanded its utility in synthesizing chiral molecules with high enantioselectivity. These advancements are pivotal in drug discovery and fine chemical synthesis.

From an environmental perspective, the biodegradability of Phenol, 3-butyl- has been a subject of interest. Studies indicate that under aerobic conditions, the compound can be metabolized by microorganisms into less harmful byproducts. This characteristic is crucial for assessing its environmental impact and ensuring sustainable disposal practices.

In conclusion, Phenol, 3-butyl-, with its unique chemical properties and diverse applications, continues to be a focal point in scientific research. Its role in materials science, biomedicine, and catalysis underscores its importance across multiple disciplines. As researchers delve deeper into its potential uses and optimize its production methods, this compound is poised to contribute significantly to technological advancements while maintaining eco-friendly practices.

• 1638-22-8(4-Butylphenol)
• 2589-78-8(Phenol, 4-hexadecyl-)
• 104-43-8(4-Dodecylphenol)
• 1987-50-4(4-Heptylphenol)
• 2446-69-7(4-Hexylphenol)
• 2589-79-9(4-Octadecylphenol)
• 14938-35-3(4-Pentylphenol)
• 500-66-3(Olivetol)
• 645-56-7(4-Propylphenol)
• 25401-89-2(4-Tetradecylphenol)