• 1. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 2. Evolution of shape, size, and areal density of a single plane of Si nanocrystals embedded in SiO2 matrix studied by atom probe tomography
  Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
• 3. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
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• 4. Evolution study of photo-synthesized gold nanoparticles by spectral deconvolution model: a quantitative approach
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• 5. Empowering microfluidics by micro-3D printing and solution-based mineral coating?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenethylamines

2-(4-Fluoro-phenyl)-ethyl-methyl-amine (CAS No. 405-68-5): Properties, Applications, and Market Insights

2-(4-Fluoro-phenyl)-ethyl-methyl-amine (CAS No. 405-68-5) is a fluorinated aromatic amine with significant interest in pharmaceutical and chemical research. This compound, also known as 4-fluoro-N-methylphenethylamine, features a phenyl ring substituted with a fluorine atom at the para position, coupled with an ethyl-methyl-amine side chain. Its unique structure makes it a valuable intermediate in organic synthesis and drug development.

The chemical properties of 2-(4-Fluoro-phenyl)-ethyl-methyl-amine include a molecular formula of C₉H₁₂FN and a molecular weight of 153.20 g/mol. The presence of the fluoro group enhances its lipophilicity, which is crucial for bioavailability in pharmaceutical applications. Researchers often explore its potential as a building block for central nervous system (CNS) active compounds, given its structural similarity to neurotransmitters like dopamine and serotonin.

In recent years, the demand for fluorinated organic compounds has surged due to their applications in medicinal chemistry. 2-(4-Fluoro-phenyl)-ethyl-methyl-amine is no exception, with studies highlighting its role in synthesizing novel psychoactive substances and neuroprotective agents. The compound's stability and reactivity make it a preferred choice for researchers investigating neurological disorders and mood regulation.

From a market perspective, the global interest in fluoro-phenyl derivatives is driven by advancements in personalized medicine and CNS drug development. Companies specializing in fine chemicals and pharmaceutical intermediates are increasingly stocking 2-(4-Fluoro-phenyl)-ethyl-methyl-amine to meet research demands. Its compatibility with modern synthetic techniques, such as flow chemistry and catalyzed cross-coupling reactions, further enhances its appeal.

One of the trending topics in chemical research is the exploration of sustainable synthesis methods for fluorinated compounds. 2-(4-Fluoro-phenyl)-ethyl-methyl-amine is often discussed in the context of green chemistry, where researchers aim to minimize waste and energy consumption. Innovations like electrochemical fluorination and biocatalytic approaches are being tested to produce this compound more efficiently.

Safety and regulatory compliance are critical when handling 2-(4-Fluoro-phenyl)-ethyl-methyl-amine. While it is not classified as a hazardous substance, proper laboratory practices, including the use of personal protective equipment (PPE) and fume hoods, are recommended. Researchers should also stay updated on regional regulations regarding the use and disposal of fluorinated compounds.

In summary, 2-(4-Fluoro-phenyl)-ethyl-methyl-amine (CAS No. 405-68-5) is a versatile compound with growing importance in pharmaceutical and chemical research. Its applications in CNS drug development, coupled with advancements in sustainable synthesis, position it as a key player in modern chemistry. As the demand for fluorinated intermediates rises, this compound is likely to remain a focal point for innovation and discovery.

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